Genetic Mapping of a new

Autor: Jamie L, Siders, Kayla L, Bieser, Danielle R, Hamill, Erika C, Acosta, Olivia K, Alexander, Humza I, Ali, Micah J, Anderson, Hayden R, Arrasmith, Mustafa, Azam, Nikki J, Beeman, Hassan, Beydoun, Lauren J, Bishop, Morgan D, Blair, Brianna, Bletch, Heather R, Bline, Jennifer C, Brown, Kelly M, Burns, Karina C, Calagua, Lexie, Chafin, William Ah, Christy, Carlyn, Ciamacco, Hannah, Cizauskas, Caitlyn M, Colwell, Abigail R, Courtright, Lucero, Diaz Alavez, Rayne Is, Ecret, Fatima, Edriss, Taylor G, Ellerbrock, Madison M, Ellis, Erica M, Extine, Eric, Feldman, Luke J, Fickenworth, Caroline M, Goeller, Alexis S, Grogg, Yailine, Hernandez, Abigail, Hershner, Megan M, Jauss, Leyre, Jimenez Garcia, Katey E, Franks, Ethan T, Kazubski, Emily R, Landis, Jon, Langub, Tia N, Lassek, Triet C, Le, Julia M, Lee, Daniel P, Levine, Phoebe J, Lightfoot, Natasha, Love, Ali, Maalhagh-Fard, Colin, Maguire, Brynna E, McGinnis, Bhargavi V, Mehta, Veronica, Melendrez, Zimri E, Mena, Seth, Mendell, Petra, Montiel-Garcia, Autumn S, Murry, Riley A, Newland, Ryan M, Nobles, Neha, Patel, Yashodhara, Patil, Cassidy L, Pfister, Victoria, Ramage, Mya R, Ray, Joseph, Rodrigues, Victoria C, Rodriquez, Yara, Romero, Alexandra M, Scott, Nicholas, Shaba, Samantha, Sieg, Kayla, Silva, Sahiba, Singh, Aleksandria J, Spargo, Savanna J, Spitnale, Nicole, Sweeden, Logan, Tague, Breanna M, Tavernini, Kathleen, Tran, Liselle, Tungol, Kylie A, Vestal, Amber, Wetherbee, Kayla M, Wright, Anthony T, Yeager, Rehab, Zahid, Jacob D, Kagey

Publikováno v: microPublication Biology

Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in the Drosophila eye we identified mutations that result in alterations and de-regulation of cell growth and divi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1878c94ed367199745ad5eba98387b24
https://pubmed.ncbi.nlm.nih.gov/33851093

Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates.

Autor: Gagne M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Flynn BJ; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Andrew SF; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Marquez J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Flebbe DR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Mychalowych A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Lamb E; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Davis-Gardner ME; Department of Pediatrics, Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.; Emory Vaccine Center, Emory University, Atlanta, GA, USA.; Emory National Primate Research Center, Atlanta, GA, USA., Burnett MR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Serebryannyy LA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Lin BC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Ziff ZE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Maule E; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Carroll R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Naisan M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Jethmalani Y; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Pessaint L; Bioqual, Inc., Rockville, MD, USA., Todd JM; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Case JB; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Dmitriev IP; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA., Kashentseva EA; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA., Ying B; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Dodson A; Bioqual, Inc., Rockville, MD, USA., Kouneski K; Bioqual, Inc., Rockville, MD, USA., O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Wali B; Department of Pediatrics, Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.; Emory Vaccine Center, Emory University, Atlanta, GA, USA.; Emory National Primate Research Center, Atlanta, GA, USA., Ellis M; Department of Pediatrics, Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.; Emory Vaccine Center, Emory University, Atlanta, GA, USA.; Emory National Primate Research Center, Atlanta, GA, USA., Godbole S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Laboune F; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Henry AR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Teng IT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Wang D; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Wang L; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zhou Q; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zouantchangadou S; Bioqual, Inc., Rockville, MD, USA., Van Ry A; Bioqual, Inc., Rockville, MD, USA., Lewis MG; Bioqual, Inc., Rockville, MD, USA., Andersen H; Bioqual, Inc., Rockville, MD, USA., Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Curiel DT; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA., Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Nason MC; Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Foulds KE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Suthar MS; Department of Pediatrics, Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.; Emory Vaccine Center, Emory University, Atlanta, GA, USA.; Emory National Primate Research Center, Atlanta, GA, USA., Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.; Center for Vaccines & Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA., Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ddouek@mail.nih.gov., Seder RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. rseder@mail.nih.gov.

Publikováno v: Nature immunology [Nat Immunol] 2024 Oct; Vol. 25 (10), pp. 1913-1927. Date of Electronic Publication: 2024 Sep 03.

Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays.

Autor: Mühlemann B; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany., Wilks SH; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Baracco L; Center for Pathogen Research, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Bekliz M; Department of Medicine, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.; Centre for Emerging Viral Diseases, University Hospitals of Geneva and University of Geneva, CH-1211, Geneva, Switzerland., Carreño JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Corman VM; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany., Davis-Gardner ME; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA., Dejnirattisai W; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Division of Emerging Infectious Disease, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok Noi, Bangkok 10700, Thailand., Diamond MS; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Andrew M. and Jane M. Bursky the Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO 63110, USA., Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Drosten C; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany., Eckerle I; Department of Medicine, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.; Centre for Emerging Viral Diseases, University Hospitals of Geneva and University of Geneva, CH-1211, Geneva, Switzerland.; Division of Infectious Diseases, Geneva University Hospitals, CH-1211 Geneva, Switzerland., Edara VV; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA., Ellis M; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA., Fouchier RAM; Viroscience Department, Erasmus Medical Center, 3015 Rotterdam, Netherlands., Frieman M; Center for Pathogen Research, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Godbole S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Haagmans B; Viroscience Department, Erasmus Medical Center, 3015 Rotterdam, Netherlands., Halfmann PJ; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA., Henry AR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Jones TC; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany.; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Katzelnick LC; Viral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Kawaoka Y; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Tokyo 162-8655, Japan., Kimpel J; Institute of Virology, Department of Hygiene, Microbiology and Public Health, Medical University of Innsbruck, Peter-Mayr-Str. 4b, 6020 Innsbruck, Austria., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Pathology, Cellular and Molecular Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Lai L; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA., Liu C; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford OX3 7BN, UK., Lusvarghi S; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD 20903, USA., Meyer B; Centre of Vaccinology, Department of Pathology and Immunology, University of Geneva, CH-1211 Geneva, Switzerland., Mongkolsapaya J; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford OX3 7BN, UK., Montefiori DC; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Mykytyn A; Viroscience Department, Erasmus Medical Center, 3015 Rotterdam, Netherlands., Netzl A; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Pollett S; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA., Rössler A; Institute of Virology, Department of Hygiene, Microbiology and Public Health, Medical University of Innsbruck, Peter-Mayr-Str. 4b, 6020 Innsbruck, Austria., Screaton GR; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK., Shen X; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Sigal A; Africa Health Research Institute, Durban 4001, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.; Centre for the AIDS Programme of Research in South Africa, Durban 4001, South Africa., Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Pathology, Cellular and Molecular Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Global Health and Emerging Pathogen Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Subramanian R; Office of Data Science and Emerging Technologies, Office of Science Management and Operations, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Supasa P; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Suthar MS; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA., Türeli S; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Wang W; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD 20903, USA., Weiss CD; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD 20903, USA., Smith DJ; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 May 15; Vol. 16 (747), pp. eadl1722. Date of Electronic Publication: 2024 May 15.

Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates.

Autor: Gagne M, Flynn BJ, Andrew SF, Flebbe DR, Mychalowych A, Lamb E, Davis-Gardner ME, Burnett MR, Serebryannyy LA, Lin BC, Pessaint L, Todd JM, Ziff ZE, Maule E, Carroll R, Naisan M, Jethmalani Y, Case JB, Dmitriev IP, Kashentseva EA, Ying B, Dodson A, Kouneski K, Doria-Rose NA, O'Dell S, Godbole S, Laboune F, Henry AR, Marquez J, Teng IT, Wang L, Zhou Q, Wali B, Ellis M, Zouantchangadou S, Ry AV, Lewis MG, Andersen H, Kwong PD, Curiel DT, Foulds KE, Nason MC, Suthar MS, Roederer M, Diamond MS, Douek DC, Seder RA

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 08. Date of Electronic Publication: 2023 Nov 08.

Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.

Autor: Moreno A; Emory Vaccine Center, Emory University, Atlanta, GA.; Emory National Primate Research Center, Atlanta, GA.; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA., Manning K; Emory Vaccine Center, Emory University, Atlanta, GA.; Emory National Primate Research Center, Atlanta, GA., Azeem MI; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, GA., Nooka AK; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Ellis M; Emory Vaccine Center, Emory University, Atlanta, GA.; Emory National Primate Research Center, Atlanta, GA., Manalo RJ; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA., Switchenko JM; Winship Cancer Institute, Atlanta, GA., Wali B; Emory Vaccine Center, Emory University, Atlanta, GA.; Emory National Primate Research Center, Atlanta, GA., Kaufman JL; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Hofmeister CC; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Joseph NS; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Lonial S; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Dhodapkar KM; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Dhodapkar MV; Department of Hematology/Medical Oncology, Emory University, Atlanta, GA.; Winship Cancer Institute, Atlanta, GA., Suthar MS; Emory Vaccine Center, Emory University, Atlanta, GA.; Emory National Primate Research Center, Atlanta, GA.; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.

Publikováno v: Research square [Res Sq] 2023 Sep 21. Date of Electronic Publication: 2023 Sep 21.