Výsledky vyhledávání - "Madison K. Ritter"

Immunomodulatory regulation by heat-labile enterotoxins and potential therapeutic applications

Autor: Madison K. Ritter, Robert O. Rainer, Terry D. Connell, Steven E. Fiester, Jennifer T. Grier, Mary-Peyton A. Knapp, Sergio Arce, Taylor A. Johnson

Publikováno v: Expert review of vaccines. 20(8)

Introduction: Heat-labile enterotoxins (HLTs) and their cognate ganglioside receptors have been extensively studied because of their therapeutic potential. Gangliosides play arole in modulating eff...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d0db4e0c06d7f637c951acf64053f0
https://pubmed.ncbi.nlm.nih.gov/34148503

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Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

Autor: Matthew W. McEwen, Vanessa M. Morales-Tirado, Magaly Martinez-Ferrer, Andrew S. Irvine, Samuel R. Barsh, Rachel C. Brennan, Jacqueline Flores-Otero, Zachary K. Goldsmith, Madison K. Ritter, Matthew W. Wilson, Kelley Yuan, Aileen M. Garcia-Vargas, William Coppess

Publikováno v: Investigative Ophthalmology & Visual Science

Purpose Vitreous seeding remains the primary reason for treatment failure in eyes with retinoblastoma (Rb). Systemic and intra-arterial chemotherapy, each with its own inherent set of complications, have improved salvage rates for eyes with advanced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261725439d6a43010e809de0365374ba
http://europepmc.org/articles/PMC6133233

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Abstract PO024: Differential binding of E. coli enterotoxins LT-IIa, LT-IIb and LT-IIc to human B and T cell subsets identifies a potential use as adjuvants in cancer immunotherapy

Autor: Taylor A. Johnson, Steven E. Fiester, Madison K. Ritter, Jennifer T. Grier, Terry D. Connell, Robert O. Rainer, Sergio Arce, Mary-Peyton A. Knapp

Publikováno v: Cancer Immunology Research. 9:PO024-PO024

There is an urgent need for development of new adjuvants to target and drive immune responses in cancer immunotherapies. The E. coli type-II heat-labile enterotoxins (HLEs) LT-IIa, LT-IIb and LT-IIc exhibit strong adjuvant properties with varying cap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db45e4ea8a23f1ff9067beaeb778922d
https://doi.org/10.1158/2326-6074.tumimm20-po024

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Abstract 4525: Dynamic changes in patterns of ganglioside expression characterize maturation of cytotoxic T cells and natural killer cells into effector cells and suggest a close relationship between the two cell types

Autor: Lorrie Mandell, Madison K. Ritter, Mary-Peyton A. Knapp, Sergio Arce, Natalie D. King-Lyons, Terry D. Connell, Jennifer T. Grier, Taylor A. Johnson

Publikováno v: Cancer Research. 80:4525-4525

Gangliosides are glycosphingolipids that play important regulatory roles in cell signaling. Their patterns of expression during human lymphoid cell development and differentiation, however are not not known. Here, we used the ganglioside-binding B su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::312132e9befe237a14cdc04140795434
https://doi.org/10.1158/1538-7445.am2020-4525

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Abstract A25: Differentiation of human naive T cells to various effector memory cell subtypes correlates with increased binding of the B subunit of Type-IIb heat-labile enterotoxin (LT-IIb-B5) to its cognate ganglioside receptors

Autor: Taylor A. Johnson, Terry D. Connell, Sergio Arce, Madison K. Ritter, Robert O. Rainer, Mary-Peyton A. Knapp, Nathalie D. King-Lyons

Publikováno v: Cancer Immunology Research. 8:A25-A25

The initial antigenic activation of T cells involves localization of the T-cell receptor to lipid rafts, of which gangliosides are major components. To understand the role of lipid rafts in the activation and differentiation of CD4+ and CD8+ T cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f319043b7e4c6fa380017fa6f57dd0ee
https://doi.org/10.1158/2326-6074.tumimm19-a25

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Dynamic changes in patterns of ganglioside expression characterize maturation of lymphoid lineage cells into effector cells and suggest a close relationship between CD8+ T cells and NK cells

Autor: Taylor Johnson, Mary-Peyton A. Knapp, Madison K. Ritter, Natalie D. King-Lyons, Jennifer T. Grier, Robert O Rainer, Terry D. Connell, Sergio Arce

Publikováno v: The Journal of Immunology. 204:230.10-230.10

Gangliosides are glycosphingolipids that play important regulatory roles in cell signaling and differentiation. To investigate their expression patterns during lymphoid cell development, human PBMC were stained with recombinant B subunits of LT-IIa,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09a175cc1a4c8af9e02f923ab1d496fb
https://doi.org/10.4049/jimmunol.204.supp.230.10

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Akademický článek

Immunomodulatory regulation by heat-labile enterotoxins and potential therapeutic applications.

Autor: Knapp, Mary-Peyton A., Johnson, Taylor A., Ritter, Madison K., Rainer, Robert O., Fiester, Steven E., Grier, Jennifer T., Connell, Terry D., Arce, Sergio

Publikováno v: Expert Review of Vaccines; Aug2021, Vol. 20 Issue 8, p975-987, 13p

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