Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Madison K. Kuhn"'
Autor:
Brendan K. Ball, Madison K. Kuhn, Rebecca M. Fleeman Bechtel, Elizabeth A. Proctor, Douglas K. Brubaker
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Type 2 diabetes (T2D) is implicated as a risk factor for Alzheimer’s disease (AD), the most common form of dementia. In this work, we investigated neuroinflammatory responses of primary neurons to potentially circulating, blood–brain bar
Externí odkaz:
https://doaj.org/article/498556b271e04785836d3c46ad056781
Autor:
Dong Yan Zhang, Jian Wang, Rebecca M. Fleeman, Madison K. Kuhn, Matthew T. Swulius, Elizabeth A. Proctor, Nikolay V. Dokholyan
Publikováno v:
ACS Chem Neurosci
The aggregation of the amyloid beta (Aβ) peptide is associated with Alzheimer’s disease (AD) pathogenesis. Cell membrane composition, especially monosialotetrahexosylganglioside (GM1), is known to promote the formation of Aβ fibrils, yet little i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077c7e0fbd8350d5a69d36139c1dd700
https://doi.org/10.1021/acschemneuro.2c00221
https://doi.org/10.1021/acschemneuro.2c00221
Autor:
Madison K. Kuhn, Rebecca M. Fleeman, Lynne M. Beidler, Amanda M. Snyder, Dennis C. Chan, Elizabeth A. Proctor
IntroductionNeuroinflammation and metabolic dysfunction are early alterations in Alzheimer’s disease brain that are thought to contribute to disease onset and progression. Glial activation due to protein deposition results in cytokine secretion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ac497487bcef2d8ee44d2c942d88e6
https://doi.org/10.1101/2023.04.07.536014
https://doi.org/10.1101/2023.04.07.536014
Autor:
Rebecca M Fleeman, Amanda M Snyder, Madison K Kuhn, Dennis C Chan, Grace C Smith, Nicole A Crowley, Amy C Arnold, Elizabeth A Proctor
Publikováno v:
Neurobiology of aging.
The ε4 variant of apolipoprotein E (APOE) is the strongest and most common genetic risk factor for Alzheimer’s disease (AD). While the mechanism of conveyed risk is incompletely understood, promotion of inflammation, dysregulated metabolism, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b2182a1daa304f4a5dc49260d1a416
https://pubmed.ncbi.nlm.nih.gov/36572594
https://pubmed.ncbi.nlm.nih.gov/36572594
Autor:
Justin D. Lathia, Katie M. Troike, James R. Connor, Amanda M. Snyder, Becky Webb, Madison K. Kuhn, Chachrit Khunsriraksakul, Hong Gang Wang, Elizabeth A. Proctor, Ganesh Shenoy
Publikováno v:
Neuro Oncol
Glioblastoma (GBM) remains one of the most difficult to treat malignancies facing modern medicine. The strong migratory and invasive capacity of GBM cells allows for diffuse invasion into neighboring healthy brain which presents a significant hurdle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695560c7a2213bd5b21d1a2ee33e8a0f
https://europepmc.org/articles/PMC8598759/
https://europepmc.org/articles/PMC8598759/
Autor:
Nikolay V. Dokholyan, Rebecca Fleeman, Matthew T. Swulius, Elizabeth A. Proctor, Jing Wang, Dong Yan Zhang, Madison K. Kuhn
The aggregation of amyloid beta (Aβ) peptide is associated with Alzheimer’s disease (AD) pathogenesis. Cell membrane composition, especially monosialotetrahexosylganglioside (GM1), is known to promote the formation of Aβ fibrils, yet little is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6cc4d5f7adacc98a886a40d90be0846
https://doi.org/10.1101/2021.07.22.453392
https://doi.org/10.1101/2021.07.22.453392
Autor:
Stephen C. Van Nostrand, Douglas K. Brubaker, Madison K. Kuhn, Elizabeth A. Proctor, Lisa R. Leon, Michael B. Yaffe, Shauna M. Dineen, Christopher D. Barrett, Douglas A. Lauffenburger
Publikováno v:
Journal of Thrombosis and Haemostasis
Heat stroke is a life-threatening condition characterized by loss of thermoregulation and severe elevation of core body temperature, which can cause organ failure and damage to the central nervous system. While no definitive test exists to measure he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4718781b48daceaaef5eaaaf261e97f4
Autor:
Zukowski, Emelia1 (AUTHOR), Sannella, Marco1 (AUTHOR), Rockhold, Jack Donato1 (AUTHOR), Kalantar, Gabriella H.2 (AUTHOR), Yu, Jingting3 (AUTHOR), SantaCruz‐Calvo, Sara4,5 (AUTHOR), Kuhn, Madison K.6 (AUTHOR), Hah, Nasun7 (AUTHOR), Ouyang, Ling7 (AUTHOR), Wang, Tzu‐Wen7 (AUTHOR), Murphy, Lyanne8 (AUTHOR), Marszalkowski, Heather8 (AUTHOR), Gibney, Kaleigh1 (AUTHOR), Drummond, Micah J.9 (AUTHOR), Proctor, Elizabeth A.6,10 (AUTHOR), Hasturk, Hatice11 (AUTHOR), Nikolajczyk, Barbara S.4,5 (AUTHOR), Bharath, Leena P.1 (AUTHOR) bharathl@merrimack.edu
Publikováno v:
Aging Cell. Nov2023, Vol. 22 Issue 11, p1-15. 15p.
Autor:
Kuhn, Madison K., Fleeman, Rebecca M., Beidler, Lynne M., Snyder, Amanda M., Chan, Dennis C., Proctor, Elizabeth A.
Publikováno v:
Cellular & Molecular Bioengineering; Aug2023, Vol. 16 Issue 4, p405-421, 17p
Publikováno v:
Journal of Neurochemistry; May2023, Vol. 165 Issue 4, p536-549, 14p