Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Madison Bolger-Munro"'
Autor:
Abhishek Bedi, Kate Choi, Connor Keane, Madison Bolger-Munro, Ashley R. Ambrose, Michael R. Gold
Publikováno v:
Cells, Vol 12, Iss 23, p 2704 (2023)
B cell antigen receptor (BCR) signaling induces actin cytoskeleton remodeling by stimulating actin severing, actin polymerization, and the nucleation of branched actin networks via the Arp2/3 complex. This enables B cells to spread on antigen-bearing
Externí odkaz:
https://doaj.org/article/44948d1e7c1244329765c77597acb64d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Signaling by the B cell antigen receptor (BCR) initiates actin remodeling. The assembly of branched actin networks that are nucleated by the Arp2/3 complex exert outward force on the plasma membrane, allowing B cells to form membrane protrusions that
Externí odkaz:
https://doaj.org/article/f2c8cf382449494bbfc4e48ce3da7c54
Autor:
Madison Bolger-Munro, Kate Choi, Faith Cheung, Yi Tian Liu, May Dang-Lawson, Nikola Deretic, Connor Keane, Michael R. Gold
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
When B cells encounter membrane-bound antigens, the formation and coalescence of B cell antigen receptor (BCR) microclusters amplifies BCR signaling. The ability of B cells to probe the surface of antigen-presenting cells (APCs) and respond to APC-bo
Externí odkaz:
https://doaj.org/article/e9004ca4e69f462481ed809a38b90124
Autor:
Madison Bolger-Munro, Kate Choi, Joshua M Scurll, Libin Abraham, Rhys S Chappell, Duke Sheen, May Dang-Lawson, Xufeng Wu, John J Priatel, Daniel Coombs, John A Hammer, Michael R Gold
Publikováno v:
eLife, Vol 8 (2019)
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally and coalesce into the central supr
Externí odkaz:
https://doaj.org/article/495108e2d3d348008c7a1f7e3b66fd17
Autor:
Connor Keane, May Dang-Lawson, Kate Choi, Michael R. Gold, Faith Cheung, Madison Bolger-Munro, Nikola Deretic, Yi Tian Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
When B cells encounter membrane-bound antigens, the formation and coalescence of B cell antigen receptor (BCR) microclusters amplifies BCR signaling. The ability of B cells to probe the surface of antigen-presenting cells (APCs) and respond to APC-bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6ad64e69b69275ab3b35d10e5acdf2
https://pubmed.ncbi.nlm.nih.gov/33928084
https://pubmed.ncbi.nlm.nih.gov/33928084
Autor:
Libin Abraham, John A. Hammer, Daniel Coombs, Michael R. Gold, John J. Priatel, Joshua M. Scurll, Duke Sheen, Kate Choi, Xufeng Wu, May Dang-Lawson, Madison Bolger-Munro, Rhys Chappell
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally and coalesce into the central supr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf39290b1824622a4a4e25345bce749
https://doi.org/10.7554/elife.44574
https://doi.org/10.7554/elife.44574
Autor:
Daniel Coombs, Rhys Chappell, Xufeng Wu, John A. Hammer, Joshua M. Scurll, Duke Sheen, Kate Choi, Libin Abraham, Michael R. Gold, May Dang-Lawson, John J. Priatel, Madison Bolger-Munro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b00b04a3af9b2063864cf2191b4732f
https://doi.org/10.7554/elife.44574.045
https://doi.org/10.7554/elife.44574.045
Autor:
Kate Choi, May Dang-Lawson, Daniel Coombs, Michael R. Gold, Joshua M. Scurll, Duke Sheen, Libin Abraham, Xufeng Wu, John A. Hammer, John J. Priatel, Madison Bolger-Munro, Rhys Chappell
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally and coalesce into the central supr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af92fb88b61404888b84cfed264a5726
https://doi.org/10.1101/490698
https://doi.org/10.1101/490698
Publikováno v:
Journal of Visualized Experiments.
B cells that bind to membrane-bound antigens (e.g., on the surface of an antigen-presenting cell) form an immune synapse, a specialized cellular structure that optimizes B-cell receptor (BCR) signaling and BCR-mediated antigen acquisition. Both the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8192025d10aa07da4285b5095e1dc7
https://doi.org/10.3791/57028-v
https://doi.org/10.3791/57028-v
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1707
In vivo, B cells are often activated by antigens that are displayed on the surface of antigen-presenting cells (APCs). Binding of membrane-associated antigens to the B cell receptor (BCR) causes rapid cytoskeleton-dependent changes in the spatial org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a4fe29cd8c04de209cca17937e6cb05
https://pubmed.ncbi.nlm.nih.gov/29388105
https://pubmed.ncbi.nlm.nih.gov/29388105