Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Madis Jakobson"'
Autor:
Anmol Kumar, Jaakko Kopra, Kärt Varendi, Lauriina L Porokuokka, Anne Panhelainen, Satu Kuure, Pepin Marshall, Nina Karalija, Mari-Anne Härma, Carolina Vilenius, Kersti Lilleväli, Triin Tekko, Jelena Mijatovic, Nita Pulkkinen, Madis Jakobson, Maili Jakobson, Roxana Ola, Erik Palm, Maria Lindahl, Ingrid Strömberg, Vootele Võikar, T Petteri Piepponen, Mart Saarma, Jaan-Olle Andressoo
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005808 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1005710.].
Externí odkaz:
https://doaj.org/article/758f22d521a842cdbb2b4a44423a1884
Autor:
Anmol Kumar, Jaakko Kopra, Kärt Varendi, Lauriina L Porokuokka, Anne Panhelainen, Satu Kuure, Pepin Marshall, Nina Karalija, Mari-Anne Härma, Carolina Vilenius, Kersti Lilleväli, Triin Tekko, Jelena Mijatovic, Nita Pulkkinen, Madis Jakobson, Maili Jakobson, Roxana Ola, Erik Palm, Maria Lindahl, Ingrid Strömberg, Vootele Võikar, T Petteri Piepponen, Mart Saarma, Jaan-Olle Andressoo
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005710 (2015)
Degeneration of nigrostriatal dopaminergic system is the principal lesion in Parkinson's disease. Because glial cell line-derived neurotrophic factor (GDNF) promotes survival of dopamine neurons in vitro and in vivo, intracranial delivery of GDNF has
Externí odkaz:
https://doaj.org/article/97fe460db77842808cd04bfe6e27a58c
Autor:
Anmol Kumar, Satu Kuure, Hannu Sariola, Yujuan Gui, Petra Sipilä, Jaan-Olle Andressoo, Hao Li, Roxana Ola, Madis Jakobson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Mechanisms controlling ureter lenght and the position of the kidney are poorly understood. Glial cell-line derived neurotrophic factor (GDNF) induced RET signaling is critical for ureteric bud outgrowth, but the function of endogenous GDNF in further
Autor:
Moritz Widmaier, Despoina Katsougkri, Joey Lai-Cheong, Reinhard Fässler, Ralph T. Böttcher, Daniel B. Rifkin, Raphael Ruppert, Emanuel Rognoni, Siegfried Ussar, Madis Jakobson, John A. McGrath
Publikováno v:
Nature medicine
Nature Medicine
Nature Medicine
Mutations in Kindlin-1 result in Kindler syndrome, which is marked by skin blistering, premature skin aging and increased risk for skin cancer. Reinhard Fassler and his colleagues have developed a new mouse model of the condition, revealing new cellu
Autor:
Madis Jakobson, Guido Posern, Maili Jakobson, Georgina P. Colo, Reinhard Fässler, Emanuel Rognoni, Christian Kupatt, Michaela-Rosemarie Hermann
Publikováno v:
Journal of Cell Science.
Integrin-mediated activation of small GTPases induces the polymerisation of G-actin into various actin structures and the release of the transcriptional co-activator MRTF from G-actin. Here we report that pan-integrin-null fibroblasts seeded on fibro
Publikováno v:
Nature. 461:1002-1006
The development of multicellular organisms requires integrin-mediated interactions between cells and their extracellular environment. Integrin binding to extracellular matrix catalyses assembly of multiprotein complexes, which transduce mechanical an
Autor:
Triin Tekko, Lauriina L. Porokuokka, Kersti Lilleväli, Nina Karalija, Mart Saarma, Roxana Ola, Kärt Varendi, Anne Panhelainen, Jaan-Olle Andressoo, Carolina Vilenius, Jelena Mijatovic, Pepin Marshall, Maria Lindahl, Anmol Kumar, Mari-Anne Härma, Satu Kuure, Ingrid Strömberg, Vootele Voikar, Maili Jakobson, T. Petteri Piepponen, Madis Jakobson, Erik Palm, Nita Pulkkinen, Jaakko Kopra
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005710 (2015)
PLoS Genetics
PLoS Genetics
Degeneration of nigrostriatal dopaminergic system is the principal lesion in Parkinson’s disease. Because glial cell line-derived neurotrophic factor (GDNF) promotes survival of dopamine neurons in vitro and in vivo, intracranial delivery of GDNF h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcaa3e8378177ef2c66722913d862d8
http://hdl.handle.net/10138/162489
http://hdl.handle.net/10138/162489
Autor:
Hannu Sariola, Jouni Kvist, Kirsi Sainio, Satu Kuure, Tiina Immonen, Karl-Heinz Braunewell, Darren Bridgewater, Nina Perälä, Roxana Ola, Dmitri Chilov, Norman D. Rosenblum, Madis Jakobson
Glial cell line-derived neurotrophic factor (GDNF) is indispensable for ureteric budding and branching. If applied exogenously, GDNF promotes ectopic ureteric buds from the Wolffian duct. Although several downstream effectors of GDNF are known, the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12526efe3212e44e7e1019640db7860
https://europepmc.org/articles/PMC3029900/
https://europepmc.org/articles/PMC3029900/
Publikováno v:
Journal of the American Society of Nephrology : JASN. 18(4)
Wnt proteins are required for induction of nephrons in mouse metanephric kidneys, but the downstream pathways that mediate tubule induction and epithelial differentiation have remained obscure. The intracellular mechanisms by which Wnt signaling medi
Autor:
Tiina Tanninen, Tiina Immonen, Mariann Nymark, Junia Y. Penachioni, Hannu Sariola, Madis Jakobson, Nina Perälä, Luca Tamagnone
Publikováno v:
Mechanisms of Development. 126:S213-S214