Oxidative stress and visual system: a review

Autor: Taurone, S., Ralli, M., Artico, M., Madia, V. N., Scarpa, S., Nottola, S. A., Maconi, A., Betti, M., Familiari, P., Nebbioso, M., Costi, R., Micera, A.

Publikováno v: EXCLI journal. 21

Different types of tissues respond differently to the action of oxidative stress. The visual system is very sensitive to oxidative action due to continuous exposure to light. In consideration of the growing interest of scientific studies towards vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bf59baa22dad28978986ec47f23623
https://pubmed.ncbi.nlm.nih.gov/35651654

Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase

Autor: Nicole Grandi, Enzo Tramontano, Francesca Esposito, Davide Ialongo, Alessandro De Leo, Giorgio Amendola, Daniela De Vita, Antonella Messore, Valentina Noemi Madia, Marie-Line Andreola, Ettore Novellino, Mathieu Métifiot, Sandro Cosconati, Roberta Costi, Angela Corona, Roberto Di Santo, Valeria Tudino, Francesco Saccoliti, Luigi Scipione

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (12), pp.8579-8598. ⟨10.1021/acs.jmedchem.1c00535⟩

Novel anti-HIV agents are still needed to overcome resistance issues, in particular inhibitors acting against novel viral targets. The ribonuclease H (RNase H) function of the reverse transcriptase (RT) represents a validated and promising target, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7119c7f6ddd81a9fee5dea8606a4e7
https://doi.org/10.1021/acs.jmedchem.1c00535