Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Madi Njie"'
Autor:
Visopo Harawa, Madi Njie, Anne Kessler, Augustine Choko, Benjamin Kumwenda, Sam Kampondeni, Michael Potchen, Kami Kim, Anthony Jaworowski, Terrie Taylor, Wilson Mandala, Karl Seydel, Stephen Rogerson
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Cerebral malaria (CM) is often fatal, and severe brain swelling is a predictor of CM-related mortality. CM is characterized by elevated circulating pro-inflammatory cytokines TNF and IFN-γ and anti-inflammatory cytokine IL-10, ho
Externí odkaz:
https://doaj.org/article/953b007b412543b68394bee1a7a4d913
Autor:
Marzieh Jabbarzare, Madi Njie, Anthony Jaworowski, Alexandra J Umbers, Maria Ome-Kaius, Wina Hasang, Louise M Randall, Bill Kalionis, Stephen J Rogerson
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236375 (2020)
BackgroundMalaria in pregnancy causes maternal, fetal and neonatal morbidity and mortality, and maternal innate immune responses are implicated in pathogenesis of these complications. The effects of malaria exposure and obstetric and demographic fact
Externí odkaz:
https://doaj.org/article/1f1b9197d65548b4b7739e6af65889b0
Autor:
Visopo Harawa, Madi Njie, Thomas Keller, Kami Kim, Anthony Jaworowski, Karl Seydel, Stephen J Rogerson, Wilson Mandala
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223410 (2019)
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in malaria is still unclear. Studies have reported an association between this cell subset and malaria symptoms and severity. Profiles of Vγ9Vδ2 γ
Externí odkaz:
https://doaj.org/article/91ca4bdc65b74d0c927629091e492205
Autor:
Jessica H Chertow, Matthew S Alkaitis, Glenn Nardone, Allison K Ikeda, Aubrey J Cunnington, Joseph Okebe, Augustine O Ebonyi, Madi Njie, Simon Correa, Shamanthi Jayasooriya, Climent Casals-Pascual, Oliver Billker, David J Conway, Michael Walther, Hans Ackerman
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005119 (2015)
Inhibition of nitric oxide (NO) signaling may contribute to pathological activation of the vascular endothelium during severe malaria infection. Dimethylarginine dimethylaminohydrolase (DDAH) regulates endothelial NO synthesis by maintaining homeosta
Externí odkaz:
https://doaj.org/article/6df109d8e2704dc1834e0a80da25a24b
Autor:
Michael Walther, Adam De Caul, Peter Aka, Madi Njie, Alfred Amambua-Ngwa, Brigitte Walther, Irene M Predazzi, Aubrey Cunnington, Susanne Deininger, Ebako N Takem, Augustine Ebonyi, Sebastian Weis, Robert Walton, Sarah Rowland-Jones, Giorgio Sirugo, Scott M Williams, David J Conway
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002579 (2012)
Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression. In many diseases including murin
Externí odkaz:
https://doaj.org/article/8d3613d8a1b44e23ab20ebc0c55d2e52
Autor:
Michael Walther, David Jeffries, Olivia C Finney, Madi Njie, Augustine Ebonyi, Susanne Deininger, Emma Lawrence, Alfred Ngwa-Amambua, Shamanthi Jayasooriya, Ian H Cheeseman, Natalia Gomez-Escobar, Joseph Okebe, David J Conway, Eleanor M Riley
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000364 (2009)
Failure to establish an appropriate balance between pro- and anti-inflammatory immune responses is believed to contribute to pathogenesis of severe malaria. To determine whether this balance is maintained by classical regulatory T cells (CD4(+) FOXP3
Externí odkaz:
https://doaj.org/article/a777c8a9b1e64f4294fbd92e9cc339de
Autor:
Ajisa Ahmadu, Dylan Allen, Kami Kim, McKenze Moss, Thomas Keller, Tonney S. Nyirenda, Innocent Kadwala, Stephen J. Rogerson, Stephen Ray, Visopo Harawa, Karl B. Seydel, Terrie E. Taylor, Iset Medina Vera, Monica Soko, Anne Kessler, Wilson L. Mandala, Madi Njie, Li-Min Ting
Publikováno v:
JCI Insight
BACKGROUND: Prediction of adverse outcomes in cerebral malaria (CM) is difficult. We hypothesized that cell-free DNA (cfDNA) levels would facilitate identification of severe and potentially fatal CM cases. METHODS: In this retrospective study, plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d42ef369ba004acba65f34505583f1
https://pubmed.ncbi.nlm.nih.gov/32554925
https://pubmed.ncbi.nlm.nih.gov/32554925
Autor:
Karl B. Seydel, Kami Kim, Visopo Harawa, Madi Njie, Anthony Jaworowski, Stephen J. Rogerson, Thomas Keller, Wilson L. Mandala
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0223410 (2019)
PLoS ONE, Vol 14, Iss 10, p e0223410 (2019)
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in malaria is still unclear. Studies have reported an association between this cell subset and malaria symptoms and severity. Profiles of Vγ9Vδ2 γ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5484cfac99a389c622a281a12b5938
https://pubmed.ncbi.nlm.nih.gov/31600250
https://pubmed.ncbi.nlm.nih.gov/31600250
Autor:
Maria Ome-Kaius, Louise M. Randall, Anthony Jaworowski, Stephen J. Rogerson, Bill Kalionis, Marzieh Jabbarzare, Madi Njie, Wina Hasang, Alexandra J. Umbers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0236375 (2020)
PLoS ONE, Vol 15, Iss 7, p e0236375 (2020)
BackgroundMalaria in pregnancy causes maternal, fetal and neonatal morbidity and mortality, and maternal innate immune responses are implicated in pathogenesis of these complications. The effects of malaria exposure and obstetric and demographic fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87effbc07ddc756e632a2f17f8a9fb3
https://doi.org/10.1371/journal.pone.0236375
https://doi.org/10.1371/journal.pone.0236375
Autor:
Aubrey J. Cunnington, Eleanor M. Riley, Simon Correa, Michael Walther, Madi Njie, Ebako N. Takem
Publikováno v:
The Journal of Immunology. 189:5336-5346
It is not known why people are more susceptible to bacterial infections such as nontyphoid Salmonella during and after a malaria infection, but in mice, malarial hemolysis impairs resistance to nontyphoid Salmonella by impairing the neutrophil oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba10a7e270faeb785a047f8d18eb2dc4
https://doi.org/10.4049/jimmunol.1201028
https://doi.org/10.4049/jimmunol.1201028