Enhancing the solubility of BCS class II drugs using mesoporous silica based formulations

Autor: Madi, Atif M. Abdelsaiad

Over the last decade, the poor water solubility of new chemical entities has become a significant issue for the pharmaceutical industry. Adequate aqueous solubility levels are essential for drugs administered via the oral route to ensure appropriate

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707823

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Metformin Hydrochloride and Sitagliptin Phosphate Fixed-Dose Combination Product Prepared Using Melt Granulation Continuous Processing Technology.

Autor: Kelleher JF; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland., Madi AM; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland., Gilvary GC; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Tian YW; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Li S; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Almajaan A; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Loys ZS; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Jones DS; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Andrews GP; Pharmaceutical Engineering Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland., Healy AM; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland. healyam@tcd.ie.

Publikováno v: AAPS PharmSciTech [AAPS PharmSciTech] 2019 Dec 12; Vol. 21 (1), pp. 23. Date of Electronic Publication: 2019 Dec 12.