Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Madhuvanthi Chandrakanthan"'
Autor:
Madhuvanthi Chandrakanthan, Toan Quoc Nguyen, Zafrul Hasan, Sneha Muralidharan, Thiet Minh Vu, Aaron Wei Liang Li, Uyen Thanh Nha Le, Hoa Thi Thuy Ha, Sang-Ha Baik, Sock Hwee Tan, Juat Chin Foo, Markus R. Wenk, Amaury Cazenave-Gassiot, Federico Torta, Wei Yi Ong, Mark Yan Yee Chan, Long N. Nguyen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The mechanisms by which platelets release sphingosine-1-phosphate (S1P) is not well characterized. Here the authors show that Mfsd2b is required for S1P release from both resting and activated platelets and that deletion of Mfsd2b impairs thrombotic
Externí odkaz:
https://doaj.org/article/e716e244e510455898a0ba23f1fb858d
Autor:
Sneha Muralidharan, Long N. Nguyen, Thiet Minh Vu, Juat Chin Foo, Aaron Wei Liang Li, Mark Y. Chan, Toan Quoc Nguyen, Zafrul Hasan, Sang-Ha Baik, Madhuvanthi Chandrakanthan, Wei-Yi Ong, Amaury Cazenave-Gassiot, Markus R. Wenk, Sock Hwee Tan, Uyen Thanh Nha Le, Hoa Thi Thuy Ha, Federico Torta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
We recently discovered that Mfsd2b, which is the S1P exporter found in blood cells. Here, we report that Mfsd2b is critical for the release of all S1P species in both resting and activated platelets. We show that resting platelets store S1P in the cy
Autor:
Galbada Sirimal Arachchige Premakumara, Selvaluxmy Kathirgamanathar, Shiroma M. Handunnetti, Madhuvanthi Chandrakanthan
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
This study aimed at investigating the anti-inflammatory potential of essential oil from rhizome and leaf of Alpinia calcarata Rosc. (ACEO) with the focus of its topical anti-inflammatory activity along with its dominant compounds 1,8-cineole and α-t
Autor:
Kai Qi Wang, Xiu Ru Toh, Aharon Schif, Francesca Clementina Radio, Bruno Dallapiccola, Zafrul Hasan, Madhuvanthi Chandrakanthan, Karin Weiss, Pazhanichamy Kalailingam, Toan Q. Nguyen, Clair Habib, Long N. Nguyen
Publikováno v:
J Clin Invest
Several missense mutations in the orphan transporter FLVCR2 have been reported in Fowler syndrome. Affected subjects exhibit signs of severe neurological defects. We identified the mouse ortholog Mfsd7c as a gene expressed in the blood-brain barrier.
Publikováno v:
British Journal of Pharmacology. 175:3741-3746
Sphingosine-1-phosphate (S1P) is an essential, bioactive lysophospholipid mediator that regulates various physiological functions such as lymphocyte trafficking, inflammation and behavioural characteristics of the vascular system. S1P signalling is m