Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Madhusoodana P. Nambiar"'
Autor:
Rita eDe Gasperi, Miguel A. Gama Sosa, Soong Ho Kim, John W Steele, Michael C Shaughness, Eric eMaudlin-Jeronimo, Aaron A Hall, Steven T DeKosky, Richard M McCarron, Madhusoodana P Nambiar, Sam eGandy, Stephen Thomas Ahlers, Gregory A Elder
Publikováno v:
Frontiers in Neurology, Vol 3 (2012)
Blast-induced traumatic brain injury (TBI) has been a major cause of morbidity and mortality in the conflicts in Iraq and Afghanistan. How the primary blast wave affects the brain is not well understood. In particular, it is unclear whether blast inj
Externí odkaz:
https://doaj.org/article/4a93b3c1306f4f1894b3fb3816a9d386
Autor:
Peethambaran Arun, Samuel Oguntayo, Yonas Alamneh, Cary Honnold, Ying Wang, Manojkumar Valiyaveettil, Joseph B Long, Madhusoodana P Nambiar
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33798 (2012)
Explosive blast results in multiple organ injury and polytrauma, the intensity of which varies with the nature of the exposure, orientation, environment and individual resilience. Blast overpressure alone may not precisely indicate the level of body
Externí odkaz:
https://doaj.org/article/43ca07f30f1047c0a22e1ed60aa6b371
Autor:
Yuan-Ping Pang, Jon Davis, Shaohua Wang, Jewn Giew Park, Madhusoodana P Nambiar, James J Schmidt, Charles B Millard
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10129 (2010)
Botulinum neurotoxin serotype A (BoNTA) causes a life-threatening neuroparalytic disease known as botulism that could afflict large, unprotected populations if the toxin were employed in an act of bioterrorism. Current post-exposure therapy is limite
Externí odkaz:
https://doaj.org/article/766b09858f2d41ee8f6c07a5a554572f
Autor:
Madhusoodana P. Nambiar, Samuel Oguntayo, Ying Wang, Joseph B. Long, Irene D. Gist, Peethambaran Arun, Stephen Van Albert
Publikováno v:
Neuroscience Letters. 609:152-158
Dephosphorylation of phosphorylated Tau (pTau) protein, which is essential for the preservation of neuronal microtubule assemblies and for protection against trauma-induced tauopathy and chronic traumatic encephalopathy (CTE), is primarily achieved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de51f8e66e44f8a41667359e9597d4bc
Autor:
Manojkumar Valiyaveettil, Joseph B. Long, Peethambaran Arun, Ying Wang, Robert Gharavi, Madhusoodana P. Nambiar, Samue Oguntayo, Yanling Wei
Publikováno v:
Journal of Neurotrauma. 31:498-504
The pathophysiology of blast-induced traumatic brain injury (TBI) and subsequent behavioral deficits are not well understood. Unraveling the mechanisms of injury is critical to derive effective countermeasures against this form of neurotrauma. Preser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ebbf329998a3b19ff61cba6a13430c
https://doi.org/10.1089/neu.2013.3074
https://doi.org/10.1089/neu.2013.3074
Autor:
Peethambaran Arun, Manoj Valiyaveettil, Joseph B. Long, Samuel Oguntayo, Yonas Alamneh, Yanling Wei, Madhusoodana P. Nambiar, Ying Wang
Publikováno v:
Brain Research. 1549:32-41
Repeated blast exposures commonly induce traumatic brain injury (TBI) characterized by diffuse axonal injury (DAI). We hypothesized that degradation of cytoskeletal proteins in the brain can lead to DAI, and evaluated α-II spectrin degradation in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e886150ce13a65ed3801f2af60a07db4
https://doi.org/10.1016/j.brainres.2013.12.031
https://doi.org/10.1016/j.brainres.2013.12.031
Autor:
Samuel Oguntayo, Manojkumar Valiyaveettil, Rania Abu-Taleb, Peethambaran Arun, Joseph B. Long, Ying Wang, Madhusoodana P. Nambiar
Publikováno v:
Journal of Neurotrauma. 30:1645-1651
Use of improvised explosive devices has significantly increased the incidence of traumatic brain injury (TBI) and associated neuropsychiatric deficits in the recent wars in Iraq and Afghanistan. Acute deleterious effects of single and repeated blast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e884ac96692fc079812c54fc412b0f15
https://doi.org/10.1089/neu.2012.2834
https://doi.org/10.1089/neu.2012.2834
Autor:
Manojkumar Valiyaveettil, Yumin Zhang, Joseph B. Long, Madhusoodana P. Nambiar, Peethambaran Arun, Rania Abu-Taleb, Samuel Oguntayo, Mikiei Tanaka, Ying Wang
Publikováno v:
Neuroscience Letters. 552:87-91
Glial fibrillary acidic protein (GFAP), a protein enriched in astrocytes, and Tau, a protein abundant in neuronal microtubules, are being widely studied as biomarkers of brain injury, and persistent severity-dependent increases in brain and blood hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75d63fb422cd9337a55b930c28b0525
https://doi.org/10.1016/j.neulet.2013.07.047
https://doi.org/10.1016/j.neulet.2013.07.047
Publikováno v:
Chemico-Biological Interactions. 203:120-124
The neuropathologic mechanisms after exposure to lethal doses of nerve agent are complex and involve multiple biochemical pathways. Effective treatment requires drugs that can simultaneously protect by reversible binding to the acetylcholinesterase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4950f36e0d0a708f0b2c524d82776185
https://doi.org/10.1016/j.cbi.2012.10.016
https://doi.org/10.1016/j.cbi.2012.10.016