Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Madhuri Singal"'
Autor:
Jessica Ponder, Ramya Rajagopal, Madhuri Singal, Nancy Baker, Grace Patlewicz, Erwin Roggen, Stella Cochrane, Kristie Sullivan
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Despite decades of investigation, test methods to identify respiratory sensitizers remain an unmet regulatory need. In order to support the evaluation of New Approach Methodologies in development, we sought to establish a reference set of low molecul
Externí odkaz:
https://doaj.org/article/46e3e9bca49c46d8ba034f5b75ba15c2
Publikováno v:
Toxicology Letters. 332:181-191
Trans-1233zd was developed as a refrigerant and propellant in consumer products; its toxicity has been studied extensively. The scope of this assessment is to apply the confirmed NOAEC to conduct Benchmark Dose Modeling (BMD) and determine the Point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea4d36addd33a777b0e622c505066b6
https://doi.org/10.1016/j.toxlet.2020.05.034
https://doi.org/10.1016/j.toxlet.2020.05.034
Autor:
William R. Troy, Thomas G. Osimitz, Pamela Dalton, Mark J. Utell, Steve Horenziak, Farah K. Ahmed, Madhuri Singal, Rachel S. Herz, Mary B. Johnson, J. R. Wells, Steven E. Prawer, Shan Yin, Richard L. Kingston
Publikováno v:
Inhalation Toxicology. 31:12-24
Seventy-one percent of US households purchase air care products. Air care products span a diverse range of forms, including scented aerosol sprays, pump sprays, diffusers, gels, candles, and plug-ins. These products are used to eliminate indoor malod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c6bcbec423eed96f8b93e21aaf4e30a
https://doi.org/10.1080/08958378.2019.1597221
https://doi.org/10.1080/08958378.2019.1597221
Autor:
Christie M. Sayes, Madhuri Singal
Publikováno v:
Journal of Aerosol Science. 151:105677
Traditional in vivo inhalation studies to inform hazard identification and risk assessment are time-intensive and financially expensive. Cell culture models combined with aerosol exposure systems have shown promise as surrogates in screening assays w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e187ff05b1d791fff4d4f7d93b263c
https://doi.org/10.1016/j.jaerosci.2020.105677
https://doi.org/10.1016/j.jaerosci.2020.105677
Autor:
Madhuri Singal, Julia S. Kimbell, Bahman Asgharian, Jeffry D. Schroeter, Lambros Kromidas, Owen T. Price
Publikováno v:
Journal of Aerosol Science. 95:15-29
Inhaled airborne droplets may undergo phase change as they travel through the respiratory tract. Droplet evaporation and condensation depends on the physicochemical and thermodynamic properties of the aerosol and will impact deposition in the respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb6c8f3e24f4e34e66e0c29034c138f6
https://doi.org/10.1016/j.jaerosci.2016.01.006
https://doi.org/10.1016/j.jaerosci.2016.01.006
Publikováno v:
Inhalation Toxicology. 24:182-193
Inhaled vapors may be absorbed at the alveolar-capillary membrane and enter arterial blood flow to be carried to other organs of the body. Thus, the biological effects of inhaled vapors depend on vapor uptake in the lung and distribution to the rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718cc9eb443abf4460360122da2bd366
https://doi.org/10.3109/08958378.2012.654857
https://doi.org/10.3109/08958378.2012.654857
Publikováno v:
Journal of Aerosol Science. 43:31-44
Computational fluid dynamics (CFD) simulations were conducted in a model of the complete nasal passages of an adult male Sprague-Dawley rat to predict regional deposition patterns of inhaled particles in the size range of 1 nm to 10 μm. Steady-state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0401c47b06cc27d2bbb1f97df21d3f0
https://doi.org/10.1016/j.jaerosci.2011.08.008
https://doi.org/10.1016/j.jaerosci.2011.08.008
Autor:
Julia S. Kimbell, O. T. Price, Madhuri Singal, Jeffry D. Schroeter, Bahman Asgharian, L. Jones
Publikováno v:
Annals of Biomedical Engineering. 39:1788-1804
Evaluation of vapor uptake by lung airways and subsequent dose to lung tissues provides the bridge connecting exposure episode to biological response. Respiratory vapor absorption depends on chemical properties of the inhaled material, including solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627a37d73f8ee4267de588d2a2839b16
https://doi.org/10.1007/s10439-011-0274-9
https://doi.org/10.1007/s10439-011-0274-9
Autor:
Saurabh Aggarwal, Jason H.T. Bates, Stephen M. Black, Peter F. Bove, James S. Brown, Jared M. Brown, Gary R. Burleson, Stefanie C.M. Burleson, Florence G. Burleson, Alejandro Castañeda, James F. Collawn, Donald N. Cook, Daniel L. Costa, Elvira C. Covarrubias, James D. Crapo, Albert van der Vliet, Aimen K. Farraj, Jane E. Farrington, Robert B. Fick, Aron B. Fisher, Henry J. Forman, W. Michael Foster, Peter Gehr, Andrew J. Gow, Christine M. Gross, Ryan Hadley, Jack R. Harkema, Mehdi Saeed Hazari, Daniel Hirsch, Dallas M. Hyde, Victor J. Johnson, James H. Jones, Pranita Katwa, Murat Kaynar, Debra L. Laskin, Jeffrey D. Laskin, Hui-Hua Li, James D. Londino, Kim E. Longworth, Michael I. Luster, Rama Malaviya, Mark D. Mannie, Andrew T. Mariassy, Sadis Matalon, Stephanie A. Matthes, John T. McBride, Robert R. Mercer, John B. Morris, Hideki Nakano, Stephen G. Olmstead, Janice L. Peake, Kent E. Pinkerton, Bruce R. Pitt, Charles G. Plopper, Robert J. Porcelli, Scott H. Randell, Susan D. Reynolds, Jesse Roman, Philip L. Sannes, Rashmin C. Savani, Richard B. Schlesinger, Madhuri Singal, Suzette Smiley-Jewell, Bernd W. Spur, Claudette M. St. Croix, Judith A. St. George, Jeffrey S. Tepper, Kalidasan Thambiayya, Michael R. Van Scott, Laura S. Van Winkle, Peter D. Wagner, Karla A. Wasserloos, Barry Weinberger, Eric S. White, Kingsley Yin, Berran Yucesoy, Graeme R. Zosky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e62b89829d56b396361a4a90abe8368
https://doi.org/10.1016/b978-0-12-404577-4.01002-x
https://doi.org/10.1016/b978-0-12-404577-4.01002-x
Autor:
Madhuri Singal
The respiratory tract and lungs are part of a complex organ system, the cardiorespiratory system, designed to facilitate the exchange of gases, such as oxygen and carbon dioxide, maintain acid–base and electrolyte imbalance, and serve as an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f1f6d9e00358c35c277464daa2e255
https://doi.org/10.1016/b978-0-12-404577-4.00031-x
https://doi.org/10.1016/b978-0-12-404577-4.00031-x