Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Madhuri Manpadi"'
Autor:
Madhuri Manpadi, Mikhail Yu. Antipin, Paul Tongwa, Jeff Altig, Willem A. L. van Otterlo, Antonio Evidente, Artem S. Kireev, Igor V. Magedov, Alexander Kornienko
Publikováno v:
The Journal of Organic Chemistry. 74:7122-7131
Pancratistatin is a phenanthridone-type natural product isolated from several plants of the Amaryllidaceae family. Its potent antiproliferative, antivascular, antiviral, and antiparasitic properties have attracted the attention of synthetic, biologic
Autor:
Madhuri Manpadi, Allison McCarthy, Jake R. Zimmerman, Olivia Johntony, Samantha Bouhall, Brian J. Myers
Publikováno v:
Tetrahedron Letters. 55:936-940
In this study, we report a two-step, one pot tandem microwave-assisted reaction of 3-formylchromones with aminopyrazoles followed by a tin-free radical addition. A library of alkyl substituted dihydropyrazolopyrimidines was prepared using this new pr
Publikováno v:
Angewandte Chemie. 125:11430-11461
Sechzig Jahre sind vergangen, seit Eschenmoser und Frey den Archetyp der C-C-Fragmentierung beschrieben. Rasch folgten neue Fragmentierungen und mehrere Varianten des Originals. Viele dieser Variationen, einschlieslich der Beckmann-, Grob-, Wharton-,
Autor:
Lawrence J. Williams, Novruz G. Ahkmedov, Hiyun Kim, Rojita Sharma, Yue Zhang, Madhuri Manpadi
Publikováno v:
Organic Letters. 13:3352-3355
Allene epoxide formation/opening reaction sequences enabled direct access to diverse products. Described here are a single flask procedure for allene preparation and allene oxidation/derivatization reactions that give, among others, diendiol, diyndio
Autor:
Madhuri Manpadi, Alexander Kornienko
Publikováno v:
Organic Preparations and Procedures International. 40:107-161
(2008). TOTAL SYNTHESES OF PANCRATISTATIN. A REVIEW. Organic Preparations and Procedures International: Vol. 40, No. 2, pp. 107-161.
Autor:
Elena A. Rozhkova, Eerik M. Elias, Madhuri Manpadi, Jennifer D. Bettale, Snezna Rogelj, Alexander Kornienko, Nikolai M. Przheval’skii, Nikolai M. Evdokimov, Marcia A. Ogasawara, Igor V. Magedov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:3872-3876
4-Arylpyrano-[3,2-c]-pyridones have been prepared by a one-step cyclocondensation of 4-hydroxy-1,6-dimethylpyridin-2(1H)-one with various substituted benzaldehydes and malononitrile. These heterocycles exhibit micromolar and submicromolar antiprolife
Autor:
Madhuri Manpadi, Alexander Kornienko
Publikováno v:
Tetrahedron Letters. 46:4433-4437
Various substituted arylcuprates undergo stereocontrolled additions to a d -mannitol-derived γ-alkoxy-α,β-enoate with exclusive anti-selectivity. The method is well suited for the preparation of a broad range of biologically active Amaryllidaceae
Publikováno v:
Tetrahedron Letters. 53:4782-4784
A simple microwave-assisted method for the conversion of carboxylic acids to MTM esters is presented. This new process allows for rapid introduction of an MTM ester protecting group to a variety of carboxylic acids including alkyl, electron-rich arom
Autor:
Brian J. Myers, Madhuri Manpadi, Jake R. Zimmerman, Olivia Johntony, Samantha Bouhall, Allison McCarthy
Publikováno v:
ChemInform. 45
In this study, we report a two-step, one pot tandem microwave-assisted reaction of 3-formylchromones with aminopyrazoles followed by a tin-free radical addition. A library of alkyl substituted dihydropyrazolopyrimidines was prepared using this new pr
Publikováno v:
ChemInform. 45
It has been 60 years since Eschenmoser and Frey disclosed the archetypal CC fragmentation reaction. New fragmentations and several variants of the original quickly followed. Many of these variations, which include the Beckmann, Grob, Wharton, Mars