Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Madhura Modak"'
Autor:
Madhura Modak, Ann-Kathrin Mattes, Daniela Reiss, Wioletta Skronska-Wasek, Rebecca Langlois, Nicolas Sabarth, Renate Konopitzky, Fidel Ramirez, Katharina Lehr, Tobias Mayr, David Kind, Coralie Viollet, Lee Kim Swee, Jutta Petschenka, Karim C. El Kasmi, Elfriede Noessner, Kerstin Kitt, Stefan Pflanz
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
In many solid cancers, tumor-associated macrophages (TAM) represent the predominant myeloid cell population. Antigen (Ag) cross-presentation leading to tumor Ag–directed cytotoxic CD8+ T cell responses is crucial for antitumor immunity. However, th
Externí odkaz:
https://doaj.org/article/4e405ca8fdb049239e02f1107be9dd50
Autor:
Ilija Crnčec, Madhura Modak, Claire Gordziel, Jasmin Svinka, Irene Scharf, Stefan Moritsch, Paulina Pathria, Michaela Schlederer, Lukas Kenner, Gerald Timelthaler, Mathias Müller, Birgit Strobl, Emilio Casanova, Editha Bayer, Thomas Mohr, Johannes Stöckl, Karlheinz Friedrich, Robert Eferl
Publikováno v:
Molecular Oncology, Vol 12, Iss 4, Pp 514-528 (2018)
The interferon‐inducible transcription factor STAT1 is a tumor suppressor in various malignancies. We investigated sex‐specific STAT1 functions in colitis and colitis‐associated colorectal cancer (CRC) using mice with specific STAT1 deletion in
Externí odkaz:
https://doaj.org/article/470ce83f7ffc4801a6ede8c87a159f05
Autor:
Alexander Puck, Katharina Radakovics, Birgit M. Reipert, Madhura Modak, Peter Steinberger, Brian A. Crowe, Sarojinidevi Künig, Johannes Stöckl, Claire Battin, Lara May, Pia Fritz
Publikováno v:
European Journal of Immunology. 51:3176-3185
The soluble cytoplasmic tail of CD45 (ct-CD45) is a cleavage fragment of CD45, that is generated during the activation of human phagocytes. Upon release to the extracellular space, ct-CD45 binds to human T cells and inhibits their activation in vitro
Autor:
Raif S. Geha, Janet Chou, Hannes Stockinger, Verena Berg, Maria Seyerl-Jiresch, Akihiro Yachie, Alexander Puck, Peter Steinberger, Gerhard J. Zlabinger, Hyeryun Choe, Sarojinidevi Künig, Madhura Modak, Markus Kraller, Brell Jennifer, Leopold Öhler, Johannes Stöckl
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Communications Biology
Communications Biology
Iron is essential for living cells. Uptake of iron-loaded transferrin by the transferrin receptor 1 (CD71, TFR) is a major but not sufficient mechanism and an alternative iron-loaded ligand for CD71 has been assumed. Here, we demonstrate that CD71 ut
Autor:
Madhura Modak, Ann-Kathrin Mattes, Daniela Reiss, Wioletta Skronska-Wasek, Rebecca Langlois, Nicolas Sabarth, Renate Konopitzky, Fidel Ramirez, Katharina Lehr, Tobias Mayr, David Kind, Coralie Viollet, Lee Kim Swee, Jutta Petschenka, Karim C. El Kasmi, Elfriede Noessner, Kerstin Kitt, Stefan Pflanz
Publikováno v:
JCI insight 7:e155022 (2022)
In many solid cancers, tumor-associated macrophages (TAM) represent the predominant myeloid cell population. Antigen (Ag) cross-presentation leading to tumor Ag-directed cytotoxic CD8+ T cell responses is crucial for anti-tumor immunity. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57199a560ab47f5946464ff95fdcc9e7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65029
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65029
Autor:
Claire Battin, Sarojinidevi Künig, Katharina Radakovics, Brian A. Crowe, Alexander Puck, Lara May, Peter Steinberger, Johannes Stöckl, Pia Fritz, Birgit M. Reipert, Madhura Modak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81999c6ab15878dc4ed557e235eab39f
https://doi.org/10.1002/eji.202149227/v2/response1
https://doi.org/10.1002/eji.202149227/v2/response1
Autor:
Ilija, Crnčec, Madhura, Modak, Claire, Gordziel, Jasmin, Svinka, Irene, Scharf, Stefan, Moritsch, Paulina, Pathria, Michaela, Schlederer, Lukas, Kenner, Gerald, Timelthaler, Mathias, Müller, Birgit, Strobl, Emilio, Casanova, Editha, Bayer, Thomas, Mohr, Johannes, Stöckl, Karlheinz, Friedrich, Robert, Eferl
Publikováno v:
Molecular Oncology
The interferon‐inducible transcription factor STAT1 is a tumor suppressor in various malignancies. We investigated sex‐specific STAT1 functions in colitis and colitis‐associated colorectal cancer (CRC) using mice with specific STAT1 deletion in
Publikováno v:
Anticancer research. 37(4)
Background CD97 is a member of the epidermal growth factor-seven transmembrane (EGF-TM7) receptor family and is dominantly expressed on immune cells and in a variety of malignant diseases. B7-H1 and B7-H3 are transmembrane proteins that are involved
Autor:
Madhura Modak, Stefan Pflanz, Nan Luo, Jirun Peng, Xianwen Ren, David Kind, Yao He, Gregory W. Peet, Kang Liu, Yanjie Han, Guojie Zhong, Xueda Hu, Michael Bergmann, Shuangjia Lu, Christian Haslinger, Ranran Gao, Weihua Zhu, Zemin Zhang, Mengmeng Xiao, Sebastian Carotta, Yilei Mao, Sid P. Kerkar, Qiming Zhang, Shashank J. Patel, Anne Vogt
Publikováno v:
Cell. 179:829-845.e20
Summary The immune microenvironment of hepatocellular carcinoma (HCC) is poorly characterized. Combining two single-cell RNA sequencing technologies, we produced transcriptomes of CD45+ immune cells for HCC patients from five immune-relevant sites: t
Autor:
Daniel Graf, Johannes Stöckl, Maria Seyerl, Madhura Modak, René Köffel, Herbert Strobl, Christopher Schuster, Karin Wagner, Nighat Yasmin, Adelheid Elbe-Bürger, Thomas Bauer
Publikováno v:
The Journal of Experimental Medicine
Bone morphogenetic protein 7 (BMP7) promotes the differentiation of Langerhans cells in the epidermis during prenatal development.
Human Langerhans cell (LC) precursors populate the epidermis early during prenatal development and thereafter unde
Human Langerhans cell (LC) precursors populate the epidermis early during prenatal development and thereafter unde