Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Madhur P, Motwani"'
Autor:
Justine Newson, Madhur P. Motwani, Alexandra C. Kendall, Anna Nicolaou, Giulio G. Muccioli, Mireille Alhouayek, Melanie Bennett, Rachel Van De Merwe, Sarah James, Roel P.H. De Maeyer, Derek W. Gilroy
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3162-3175 (2017)
Acute inflammation is characterized by granulocyte infiltration followed by efferocytosing mononuclear phagocytes, which pave the way for inflammatory resolution. Until now, it was believed that resolution then leads back to homeostasis, the physiolo
Externí odkaz:
https://doaj.org/article/523f70276412407793ee3c96b83f82bc
Autor:
Madhur P Motwani, Justine Newson, Simon Kwong, Angela Richard-Loendt, Romain Colas, Jesmond Dalli, Derek W Gilroy
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186964 (2017)
Acute inflammation is an immediate response to infection and injury characterised by the influx of granulocytes followed by phagocytosing mononuclear phagocytes. Provided the antigen is cleared and the immune system of the host is fully functional, t
Externí odkaz:
https://doaj.org/article/d69cafb1a4d1496cbd4d0b737e1e002c
Autor:
Alexander A Maini, Marc J George, Madhur P Motwani, Richard M Day, Derek W Gilroy, Alastair J O'Brien
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165502 (2016)
Defects in neutrophil function have been implicated in a wide spectrum of clinical conditions. Several models are employed to study activated human neutrophils akin to those found at a site of inflammation. These include whole blood (WB) ex vivo stim
Externí odkaz:
https://doaj.org/article/35df6ce0dc3f4d4a8217e6ec97422d68
Autor:
Derek W. Gilroy, Riccardo Wysoczanski, Sara McCartney, Daniel Marks, Anthony W. Segal, R. Vega, Alexandra C. Kendall, Farooq Rahman, Stuart Bloom, Madhur P. Motwani, Anna Nicolaou
The cause of chronic inflammation in ulcerative colitis (UC) is incompletely understood. Here we tested the hypothesis that an excessive acute inflammatory response to bacteria contributes to the pathogenesis. Acute inflammatory responses were provok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56eaaa163db872a89bad28dab479bd2
Autor:
Alexandra C. Kendall, Melanie Bennett, Derek W. Gilroy, Justine Newson, Rachel C van de Merwe, Sarah James, Giulio G. Muccioli, Mireille Alhouayek, Anna Nicolaou, Madhur P. Motwani, Roel P.H. De Maeyer
Publikováno v:
SSRN Electronic Journal.
While resolution is believed to switch inflammation off and return the affected tissues back to homeostasis, we found that it triggers a prolonged phase of immune suppression. During resolution of acute inflammation (∼72h) CD4+ and CD8+ lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d4cbbc924d35c2050190f57cb4f245
https://doi.org/10.2139/ssrn.3155910
https://doi.org/10.2139/ssrn.3155910
Autor:
Madhur P. Motwani, Derek W. Gilroy
Publikováno v:
Seminars in Immunology. 27:257-266
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2af102a19f3cbcdedd985fa1b2151db
https://doi.org/10.1016/j.smim.2015.07.002
https://doi.org/10.1016/j.smim.2015.07.002
Autor:
Adrian J. Hobbs, Raymond J. MacAllister, Alexander A. Maini, Paul C. Norris, Marc J. George, Madhur P. Motwani, Charles N. Serhan, Alice Henderson, Derek W. Gilroy, Barbara White, Frances Bennett, Mark Tepper, Justine Newson
Publikováno v:
Clinical Pharmacology and Therapeutics
Anabasum is a synthetic analog of Δ8‐tetrahydrocannabinol (THC)‐11‐oic acid that in preclinical models of experimental inflammation exerts potent anti‐inflammatory actions with minimal central nervous system (CNS) cannabimimetic activity. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf455a7da6678eec85d10f90ab5c13f
https://pubmed.ncbi.nlm.nih.gov/29238967
https://pubmed.ncbi.nlm.nih.gov/29238967
Autor:
Madhur P, Motwani, Romain A, Colas, Marc J, George, Julia D, Flint, Jesmond, Dalli, Angela, Richard-Loendt, Roel Ph, De Maeyer, Charles N, Serhan, Derek W, Gilroy
Publikováno v:
JCI insight. 3(6)
While the treatment of inflammatory disorders is generally based on inhibiting factors that drive onset of inflammation, these therapies can compromise healing (NSAIDs) or dampen immunity against infections (biologics). In search of new antiinflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2038a9dbe25b49afaeedf89729c72ab
https://pubmed.ncbi.nlm.nih.gov/29563331
https://pubmed.ncbi.nlm.nih.gov/29563331
Autor:
Madhur P, Motwani, Julia D, Flint, Roel Ph, De Maeyer, James N, Fullerton, Andrew M, Smith, Daniel Jb, Marks, Derek W, Gilroy
Publikováno v:
The Journal of Pathology: Clinical Research
Whilst numerous studies investigating the aetiology of inflammatory diseases have been performed in rodents, the applicability of these data to human pathophysiology is frequently debated. Regardless of the strengths and weaknesses of rodent models i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::185b3bdcf6e245475f8ccdb4ab8229b9
https://pubmed.ncbi.nlm.nih.gov/27499924
https://pubmed.ncbi.nlm.nih.gov/27499924
Autor:
Anna Nicolaou, Roser Vega, Madhur P. Motwani, Alexandra C. Kendall, Sara McCartney, Daniel Marks, Riccardo Wysoczanski, Stuart Bloom, Derek W. Gilroy, Farooq Rahman, Anthony W. Segal
Publikováno v:
Gastroenterology. 152:S996-S997
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22645cfd6599483fd8492d03dfc165c3
https://doi.org/10.1016/s0016-5085(17)33377-2
https://doi.org/10.1016/s0016-5085(17)33377-2