Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Madhumita Mahalanabis"'
Autor:
Catherine M. Klapperich, Nira R. Pollock, Jessie Chang, Madhumita Mahalanabis, Lena Liu, Jane Yuqian Zhang
Publikováno v:
Diagnostics, Vol 3, Iss 1, Pp 155-169 (2013)
We report a disposable and highly effective polymeric microfluidic viral sample concentration device capable of increasing the concentration of virus in a human nasopharyngeal specimen more than one order of magnitude in less than 30 min without the
Externí odkaz:
https://doaj.org/article/91aed1b6eef44963acbe67c3a651f432
Autor:
Shichu Huang, Jaephil Do, Madhumita Mahalanabis, Andy Fan, Lei Zhao, Lisa Jepeal, Satish K Singh, Catherine M Klapperich
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60059 (2013)
In order to counter the common perception that molecular diagnostics are too complicated to work in low resource settings, we have performed a difficult sample preparation and DNA amplification protocol using instrumentation designed to be operated w
Externí odkaz:
https://doaj.org/article/cd30a07b3191436991519cb09787dcf8
Autor:
Qingqing Cao, Madhumita Mahalanabis, Jessie Chang, Brendan Carey, Christopher Hsieh, Ahjegannie Stanley, Christine A Odell, Patricia Mitchell, James Feldman, Nira R Pollock, Catherine M Klapperich
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33176 (2012)
A rapid, low cost, accurate point-of-care (POC) device to detect influenza virus is needed for effective treatment and control of both seasonal and pandemic strains. We developed a single-use microfluidic chip that integrates solid phase extraction (
Externí odkaz:
https://doaj.org/article/dd889ec4207747e7a5d983a17a17a585
Autor:
Jane Yuqian Zhang, Madhumita Mahalanabis, Catherine M. Klapperich, Nira R. Pollock, Jessie Chang, Lena Liu
Publikováno v:
Diagnostics, Vol 3, Iss 1, Pp 155-169 (2013)
Diagnostics
Diagnostics; Volume 3; Issue 1; Pages: 155-169
Diagnostics
Diagnostics; Volume 3; Issue 1; Pages: 155-169
We report a disposable and highly effective polymeric microfluidic viral sample concentration device capable of increasing the concentration of virus in a human nasopharyngeal specimen more than one order of magnitude in less than 30 min without the
Publikováno v:
Food and Environmental Virology. 2:225-230
The goal of this study was to determine if a cytopathogenic effects (CPE) cell culture assay and an integrated cell culture PCR (ICC-PCR) assay would yield similar or different results when used to assess virus survival in water. Poliovirus type 1 wa
Publikováno v:
Biomedical Microdevices. 12:353-359
In the original manuscript, we reported the demonstration of an integrated microfluidic chip that performed helicase dependent amplification (HDA) on samples containing live bacteria. Bacterial lysis, nucleic acid extraction, and DNA amplification wi
Autor:
Michael O. Boylan, Catherine M. Klapperich, Chris Atkinson, John H. Schwartz, Aaron C. Bartoo, Sara Gillers, Madhumita Mahalanabis, Satish K. Singh
Publikováno v:
Journal of Microbiological Methods. 78:203-207
In this paper, we describe the design of a microfluidic sample preparation chip for human stool samples infected with Clostridium difficile. We established a polymerase chain reaction able to distinguish C. difficile in the presence of several other
Autor:
Nancy L. Haigwood, E. Michael Chester, Bruce D. Walker, Pushpa Jayaraman, Florencia Pereyra, Barbra A. Richardson, Toshiyuki Miura, Madhumita Mahalanabis
Publikováno v:
Journal of Virology. 83:662-672
We assessed differences in the character and specificity of autologous neutralizing antibodies (ANAbs) against individual viral variants of the quasispecies in a cohort of drug-naïve subjects with long-term controlled human immunodeficiency virus t
Autor:
Nancy L. Haigwood, Gary Landucci, Koen K. A. Van Rompay, Vaniambadi S. Kalyanaraman, Marjorie Robert-Guroff, Marta L. Marthas, Ruth H. Florese, Donald N. Forthal, Kris Aldrich, Madhumita Mahalanabis, David Venzon
Publikováno v:
The Journal of Immunology. 177:4028-4036
Previously, Ab-dependent cellular cytotoxicity (ADCC) was significantly correlated with reduced acute viremia upon intrarectal SIVmac251 challenge of immunized rhesus macaques. To directly assess ADCC protective efficacy, six neonatal macaques were i
Autor:
Ingrid A. Beck, Gerald H. Learn, Jennifer L. McKernan, Lisa M. Frenkel, Laura Heath, Diane M. Pawluk, Yang Wang, Paul Lewis, Giovanina M. Ellis, Nicole H. Tobin, Sarah Holte, James I. Mullins, Shannon M. De Vange, Kathleen M. Mohan, Ann J. Melvin, Wilscott E. Naugler, Madhumita Mahalanabis
Publikováno v:
Journal of Virology. 77:5721-5730
To evaluate human immunodeficiency virus type 1 (HIV-1) replication and selection of drug-resistant viruses during seemingly effective highly active antiretroviral therapy (HAART), multiple HIV-1 env and pol sequences were analyzed and viral DNA leve