β-Lactam Resistance in ESKAPE Pathogens Mediated Through Modifications in Penicillin-Binding Proteins: An Overview

Autor: Dhiviya Prabaa Muthuirulandi Sethuvel, Yamuna Devi Bakthavatchalam, Maruthan Karthik, Madhumathi Irulappan, Rahul Shrivastava, Hariharan Periasamy, Balaji Veeraraghavan

Publikováno v: Infectious Diseases and Therapy, Vol 12, Iss 3, Pp 829-841 (2023)

Abstract Bacteria acquire β-lactam resistance through a multitude of mechanisms among which production of β-lactamases (enzymes that hydrolyze β-lactams) is the most common, especially in Gram-negatives. Structural changes in the high-molecular-we

Externí odkaz: https://doaj.org/article/b762f3cd6f254fc9a2016e579bab37d7

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Glu 571 of PheT plays a pivotal role in the thermal stability of Escherichia coli PheRS enzyme.

Autor: Ashwin Sri Bala S; Department of Molecular Biology, School of Biological Sciences, Centre for Advanced Studies in Functional and Organismal Genomics, Madurai Kamaraj University (University with Potential for Excellence), Madurai, India., Madhumathi I; Department of Molecular Biology, School of Biological Sciences, Centre for Advanced Studies in Functional and Organismal Genomics, Madurai Kamaraj University (University with Potential for Excellence), Madurai, India., Vinodha S; Department of Molecular Biology, School of Biological Sciences, Centre for Advanced Studies in Functional and Organismal Genomics, Madurai Kamaraj University (University with Potential for Excellence), Madurai, India., Munavar MH; Department of Molecular Biology, School of Biological Sciences, Centre for Advanced Studies in Functional and Organismal Genomics, Madurai Kamaraj University (University with Potential for Excellence), Madurai, India.

Publikováno v: Journal of basic microbiology [J Basic Microbiol] 2018 Jun; Vol. 58 (6), pp. 475-491. Date of Electronic Publication: 2018 Apr 16.