Zobrazeno 1 - 10
of 1 570
pro vyhledávání: '"Madhumathi"'
Autor:
Irene González-Domínguez, Eduard Puente-Massaguer, Adam Abdeljawad, Tsoi Ying Lai, Yonghong Liu, Madhumathi Loganathan, Benjamin Francis, Nicholas Lemus, Victoria Dolange, Marta Boza, Stefan Slamanig, Jose Luis Martínez-Guevara, Florian Krammer, Peter Palese, Weina Sun
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract We have developed a new universal influenza B vaccination strategy based on inactivated influenza B viruses displaying mosaic hemagglutinins (mHAs). Recombinant mHA viruses were constructed by replacing the four major antigenic sites of infl
Externí odkaz:
https://doaj.org/article/e8dc8772cf89456ca4c3821cbb92e6f0
Autor:
Raveen Rathnasinghe, Lauren A. Chang, Rebecca Pearl, Sonia Jangra, Amy Aspelund, Alaura Hoag, Soner Yildiz, Ignacio Mena, Weina Sun, Madhumathi Loganathan, Nicholas Alexander Crossland, Hans P. Gertje, Anna Elise Tseng, Sadaf Aslam, Randy A. Albrecht, Peter Palese, Florian Krammer, Michael Schotsaert, Thomas Muster, Adolfo García-Sastre
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Influenza viruses pose a threat to public health as evidenced by severe morbidity and mortality in humans on a yearly basis. Given the constant changes in the viral glycoproteins owing to antigenic drift, seasonal influenza vaccines need to
Externí odkaz:
https://doaj.org/article/dccfdfa0d19945a6be803b54e7f7865b
Autor:
Nico Joel Halwe, Lea Hamberger, Julia Sehl-Ewert, Christin Mache, Jacob Schön, Lorenz Ulrich, Sten Calvelage, Mario Tönnies, Jonas Fuchs, Pooja Bandawane, Madhumathi Loganathan, Anass Abbad, Juan Manuel Carreño, Maria C. Bermúdez-González, Viviana Simon, Ahmed Kandeil, Rabeh El-Shesheny, Mohamed A. Ali, Ghazi Kayali, Matthias Budt, Stefan Hippenstiel, Andreas C. Hocke, Florian Krammer, Thorsten Wolff, Martin Schwemmle, Kevin Ciminski, Donata Hoffmann, Martin Beer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian H9N2 viruses have been increasingly reported. In 2017, an H9N2 virus was isolated
Externí odkaz:
https://doaj.org/article/27c9b3ce2fd746359b0b64d22dcabd10
Autor:
Kevin E. Ramos, Nisreen M. A. Okba, Jessica Tan, Pooja Bandawane, Philip S. Meade, Madhumathi Loganathan, Benjamin Francis, Sergey Shulenin, Frederick W. Holtsberg, M. Javad Aman, Meagan McMahon, Florian Krammer, Jonathan R. Lai
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Monoclonal antibodies (mAbs) are an attractive therapeutic platform for the prevention and treatment of influenza virus infection. There are two major glycoproteins on the influenza virion surface: hemagglutinin (HA), which is responsible fo
Externí odkaz:
https://doaj.org/article/e51458b0b781478a9593e39a21359443
Autor:
Kavon Karrobi, Anup Tank, Mohammad Ahsan Fuzail, Madhumathi Kalidoss, Karissa Tilbury, Muhammad Zaman, Jacopo Ferruzzi, Darren Roblyer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Cancer cells are mechanically sensitive to physical properties of the microenvironment, which can affect downstream signaling to promote malignancy, in part through the modulation of metabolic pathways. Fluorescence Lifetime Imaging Microsco
Externí odkaz:
https://doaj.org/article/3fa03010aebc4525a2ee46fa2491712a
Autor:
Dhiviya Prabaa Muthuirulandi Sethuvel, Yamuna Devi Bakthavatchalam, Maruthan Karthik, Madhumathi Irulappan, Rahul Shrivastava, Hariharan Periasamy, Balaji Veeraraghavan
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 3, Pp 829-841 (2023)
Abstract Bacteria acquire β-lactam resistance through a multitude of mechanisms among which production of β-lactamases (enzymes that hydrolyze β-lactams) is the most common, especially in Gram-negatives. Structural changes in the high-molecular-we
Externí odkaz:
https://doaj.org/article/b762f3cd6f254fc9a2016e579bab37d7
Autor:
Robert Haupt, Lauren Baracco, Erin M. Harberts, Madhumathi Loganathan, Lucas J. Kerstetter, Florian Krammer, Lynda Coughlan, Robert K. Ernst, Matthew B. Frieman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Influenza A virus (IAV) is a leading cause of respiratory disease worldwide often resulting in severe morbidity and mortality. We have previously shown that the Bacterial Enzymatic Combinatorial Chemistry (BECC) adjuvants, BECC438 and BECC47
Externí odkaz:
https://doaj.org/article/6cab5b2e67d042f490774188db3c9224
Autor:
Norbert Pardi, Juan Manuel Carreño, George O’Dell, Jessica Tan, Csaba Bajusz, Hiromi Muramatsu, Willemijn Rijnink, Shirin Strohmeier, Madhumathi Loganathan, Dominika Bielak, Molly M. H. Sung, Ying K. Tam, Florian Krammer, Meagan McMahon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The public health concern caused by influenza B virus is often overlooked, yet represents a significant global burden. Here, the authors evaluate the cellular and humoral immune responses of multivalent vaccine candidates, based on the lipid nanopart
Externí odkaz:
https://doaj.org/article/fee248d98d334503a705ca5bed4304ac
Autor:
Eduard Puente-Massaguer, Annika Beyer, Madhumathi Loganathan, Iden Sapse, Juan Manuel Carreño, Goran Bajic, Weina Sun, Peter Palese, Florian Krammer
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Seasonal influenza viruses account for 1 billion infections worldwide every year, including 3–5 million cases of severe illness and up to 650,000 deaths. The effectiveness of current influenza virus vaccines is variable and relies on the immunodomi
Externí odkaz:
https://doaj.org/article/79d4755682f742bc909d6415d153112d
Autor:
Madhumathi Jayaprakasam, Nabendu Chatterjee, Mohammed Mudassar Chanda, Sheikh Mohammed Shahabuddin, Monil Singhai, Simmi Tiwari, Samiran Panda
Publikováno v:
One Health, Vol 16, Iss , Pp 100564- (2023)
The disease anthrax occurs generally in herbivores and the causative organism (Bacillus anthracis) infects humans who come in contact with infected animals or their products. The persistence of anthrax spores for decades and its lethality contribute
Externí odkaz:
https://doaj.org/article/4b2e6b510a1441ed8b14ad3a868deedb