Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Madhulika Jain"'
Autor:
Madhulika Jain, Jeffery S Cox
Publikováno v:
PLoS Pathogens, Vol 1, Iss 1, p e2 (2005)
Virulent mycobacteria utilize surface-exposed polyketides to interact with host cells, but the mechanism by which these hydrophobic molecules are transported across the cell envelope to the surface of the bacteria is poorly understood. Phthiocerol di
Externí odkaz:
https://doaj.org/article/feeea32e42a54fd8bca50feadbaefb0e
The diverse array of Mycobacterium tuberculosis lipids, many of which are critical for virulence and mediate interactions with host cells, exist primarily on the outermost surface of the bacterium. Fourteen mmpL genes have been identified by analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d30604e67d7c4867cf9e889513a431d
https://doi.org/10.1128/9781555815783.ch12
https://doi.org/10.1128/9781555815783.ch12
Autor:
Gopal Datt Joshi, Madhulika Jain, S. R. Krishnadas, Jayanthi Sivaswamy, A. Ujjwaft Syed Tabish
Publikováno v:
ISBI
Optic nerve head (ONH) segmentation problem has been of interest for automated glaucoma assessment. Although various segmentation methods have been proposed in the recent past, it is difficult to evaluate and compare the performance of individual met
Publikováno v:
ICVGIP
Glaucoma is an eye disorder that causes irreversible loss of vision and is prevalent in the aging population. Glaucoma is indicated both by structural changes and presence of atrophy in retina. In retinal images, these appear in the form of subtle va
Autor:
Cynthia M. Holsclaw, Carolyn R. Bertozzi, Julie A. Leary, Michael W. Schelle, Jeffery S. Cox, Clifton D. Leigh, Sarah A. Gilmore, Madhulika Jain
Publikováno v:
ACS chemical biology, vol 7, iss 5
ACS Chemical Biology
ACS Chemical Biology
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is a highly evolved human pathogen characterized by its formidable cell wall. Many unique lipids and glycolipids from the Mtb cell wall are thought to be virulence factors that me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d695a2fb57e4580b50e2cc0901cf4ce
https://escholarship.org/uc/item/6tv006cx
https://escholarship.org/uc/item/6tv006cx
Autor:
Michael D. Leavell, Christopher J. Petzold, Jeffery S. Cox, Michael W. Schelle, Pawan Kumar, Madhulika Jain, Fiona L. Lin, Carolyn R. Bertozzi, Julie A. Leary
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(27)
Mycobacterium tuberculosisproduces numerous exotic lipids that have been implicated as virulence determinants. One such glycolipid, Sulfolipid-1 (SL-1), consists of a trehalose-2-sulfate (T2S) core acylated with four lipid moieties. A diacylated inte
Autor:
Michael W. Schelle, Julie A. Leary, Michael D. Leavell, Carolyn R. Bertozzi, Madhulika Jain, Joseph D. Mougous, Jeffery S. Cox, Christopher J. Petzold
Mycobacterium tuberculosis synthesizes specific polyketide lipids that interact with the host and are required for virulence. Using a mass spectrometric approach to simultaneously monitor hundreds of lipids, we discovered that the size and abundance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b75ad1cc857f17bad93fe65f7f2fc54
https://europepmc.org/articles/PMC1829275/
https://europepmc.org/articles/PMC1829275/
Autor:
Ryan H. Senaratne, Christopher J. Petzold, Joseph D. Mougous, Lee W. Riley, Madhulika Jain, Michael D. Leavell, Carolyn R. Bertozzi, Michael W. Schelle, Julie A. Leary, Jeffery S. Cox, Dong H. Lee
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(11)
Sulfated molecules have been shown to modulate isotypic interactions between cells of metazoans and heterotypic interactions between bacterial pathogens or symbionts and their eukaryotic host cells.Mycobacterium tuberculosis, the causative agent of t
Autor:
Jeffery S. Cox, Madhulika Jain
Publikováno v:
PLoS pathogens, vol 1, iss 1
PLoS Pathogens, Vol 1, Iss 1, p e2 (2005)
PLoS Pathogens
PLoS Pathogens, Vol 1, Iss 1, p e2 (2005)
PLoS Pathogens
Virulent mycobacteria utilize surface-exposed polyketides to interact with host cells, but the mechanism by which these hydrophobic molecules are transported across the cell envelope to the surface of the bacteria is poorly understood. Phthiocerol di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7a36d12f10e6d5a598688cd78295db
https://escholarship.org/uc/item/40x1q7ws
https://escholarship.org/uc/item/40x1q7ws
Publikováno v:
The Journal of biological chemistry. 280(24)
There is growing interest in understanding how the cellular environment affects protein folding mechanisms, but most spectroscopic methods for monitoring folding in vitro are unsuitable for experiments in vivo or in other complex mixtures. Monoclonal