Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Madhulika Chandra"'
Autor:
Detlef Wencker, Richard N. Kitsis, Khanh Nguyen, Stephen M. Factor, Jamshid Shirani, Stavros Garantziotis, Wenfeng Miao, Madhulika Chandra, Robert C. Armstrong
Publikováno v:
Journal of Clinical Investigation. 111:1497-1504
Heart failure is a common, lethal condition whose pathogenesis is poorly understood. Recent studies have identified low levels of myocyte apoptosis (80-250 myocytes per 10(5) nuclei) in failing human hearts. It remains unclear, however, whether this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac3da0684b0ea329fefc571e5edc9f8
https://doi.org/10.1172/jci17664
https://doi.org/10.1172/jci17664
Autor:
Michael P. Lisanti, Stephen M. Factor, Jamshid Shirani, Scott Eric Woodman, Richard N. Kitsis, Terrence M. Williams, Robert G. Russell, David S. Park, Linda A. Jelicks, Herbert B. Tanowitz, Louis M. Weiss, Baiyu Tang, Andrea Pereira De Souza, Vitaliy Shtutin, Madhulika Chandra, Alex W. Cohen
Publikováno v:
American Journal of Physiology-Cell Physiology. 284:C457-C474
Recently, development of a caveolin-1-deficient (Cav-1 null) mouse model has allowed the detailed analysis of caveolin-1's function in the context of a whole animal. Interestingly, we now report that the hearts of Cav-1 null mice are markedly abnorma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae716e7e3a2466494afb6d5a2750f33d
https://doi.org/10.1152/ajpcell.00380.2002
https://doi.org/10.1152/ajpcell.00380.2002
Publikováno v:
Frontiers in Bioscience. 8:e323-336
Acute myocarditis can be caused by a variety of organisms. Congestive heart failure and death may occur as a consequence of these infections. In recent years cardiac imaging, by echocardiography and magnetic resonance and nuclear imaging has become a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aca6542342ad4da28b393fee807a5e
https://doi.org/10.2741/1050
https://doi.org/10.2741/1050
Autor:
Huan Huang, Vitaliy Shtutin, Masashi Yanagisawa, Jamshid Shirani, Yaz Y. Kisanuki, Stephen M. Factor, Linda A. Jelicks, Richard G. Pestell, Herbert B. Tanowitz, Louis M. Weiss, Madhulika Chandra, Murray Wittner
Publikováno v:
Clinical Science. 103:263S-266S
Trypanosoma cruzi is the aetiological agent of Chagas' disease, an important cause of chronic cardiomyopathy. We previously demonstrated a role for endothelin-1 (ET-1) in the pathogenesis of chagasic heart disease. In order to explore further the sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34acaaf3448af62b5cfeb95f0d8e16a
https://doi.org/10.1042/cs103s263s
https://doi.org/10.1042/cs103s263s
Autor:
Jamshid Shirani, Philippe G. Frank, Baiyu Tang, William Schubert, David S. Park, Stephen M. Factor, Scott Eric Woodman, Madhulika Chandra, Alex W. Cohen, Linda A. Jelicks, Michael P. Lisanti, Louis M. Weiss, Herbert B. Tanowitz, Babak Razani
Publikováno v:
The American Journal of Pathology. 160:2207-2217
The caveolin gene family consists of caveolins 1, 2, and 3. Caveolins 1 and 2 are co-expressed in many cell types, such as endothelial cells, fibroblasts, smooth muscle cells and adipocytes, where they form a heteroligomeric complex. In contrast, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c9b9d94cfb89fbabdde39ce6bf5fe0
https://doi.org/10.1016/s0002-9440(10)61168-6
https://doi.org/10.1016/s0002-9440(10)61168-6
Publikováno v:
Journal of the American Society of Echocardiography. 14:853-862
Characterization of the severity of aortic stenosis relies on accurate measurement of the pressure gradient across the valve and the valve area. Pressure gradients measured by Doppler ultrasound based on the clinical form of the Bernoulli equation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0663cc7f18d151e97fb4c7775b709196
https://doi.org/10.1067/mje.2001.113648
https://doi.org/10.1067/mje.2001.113648
Autor:
Stephen M. Factor, Herbert B. Tanowitz, Vicki L. Braunstein, Linda A. Jelicks, Stephen A. Morris, Nigel Yarlett, Murray Wittner, Huan Huang, John Chan, Cyrus J. Bacchi, Louis M. Weiss, Jamshid Shirani, Madhulika Chandra
Publikováno v:
Journal of Molecular and Cellular Cardiology. 31:75-88
Expression of Cardiac Cytokines and Inducible Form of Nitric Oxide Synthase (NOS2) in Trypanosoma cruzi-infected Mice. Journal of Molecular and Cellular Cardiology (1999) 31, 75-88. Both cardiac cytokine and inducible nitric oxide synthase (NOS2) exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf3c1d35bb40f074a15f30c65ab14e1
https://doi.org/10.1006/jmcc.1998.0848
https://doi.org/10.1006/jmcc.1998.0848
Autor:
Yaz Y. Kisanuki, George J. Christ, Louis M. Weiss, Stephen M. Factor, Linda A. Jelicks, Jamshid Shirani, Richard N. Kitsis, Madhulika Chandra, Huan Huang, Herbert B. Tanowitz, Maria L. Loredo, Murray Wittner, Vitaliy Shtutin, Masashi Yanagisawa, Shankar Mukherjee
On the basis of previous observations, endothelin 1 (ET-1) has been suggested as contributing to the pathogenesis of Chagasic cardiomyopathy. Therefore, ET-1 flox/flox ;α-MHC-Cre(+) mice in which the ET-1 gene was deleted from cardiac myocytes and E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3bfc065ed766aa87760e11d53fb1af
https://europepmc.org/articles/PMC1087455/
https://europepmc.org/articles/PMC1087455/
Autor:
Alex W. Cohen, Stephen M. Factor, Madhulika Chandra, Louis M. Weiss, Jamshid Shirani, Baiyu Tang, Andrea Pereira De Souza, Hyangkyu Lee, David S. Park, Philippe G. Frank, Babak Razani, Terence M. Williams, Michael P. Lisanti, Herbert B. Tanowitz, Linda A. Jelicks
Publikováno v:
Biochemistry. 42(51)
Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane found in most cell types. Caveolin-1 is the principal protein component of caveolae membranes in nonmuscle cells. The recent development of Cav-1-deficient mice has allowed inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961e43c15ec81c525fca2bd3c114b64f
https://pubmed.ncbi.nlm.nih.gov/14690422
https://pubmed.ncbi.nlm.nih.gov/14690422
Autor:
Wenfeng Miao, Richard N. Kitsis, Joan Heller Brown, Robert C. Armstrong, Madhulika Chandra, Yukihiro Hayakawa, Jamshid Shirani, Gerald W. Dorn
Publikováno v:
Circulation. 108(24)
Background— Although the occurrence of cardiac myocyte apoptosis during heart failure has been documented, its importance in pathogenesis is unknown. Transgenic mice with cardiac-restricted overexpression of Gαq exhibit a lethal, peripartum cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e6b95e6ae1472d01ac86e54e4e757f
https://pubmed.ncbi.nlm.nih.gov/14676135
https://pubmed.ncbi.nlm.nih.gov/14676135