Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Madhulika, Sharma"'
Autor:
Wendy A. Lea, Thomas Winklhofer, Lesya Zelenchuk, Madhulika Sharma, Jessica Rossol-Allison, Timothy A. Fields, Gail Reif, James P. Calvet, Jason L. Bakeberg, Darren P. Wallace, Christopher J. Ward
Publikováno v:
Cells, Vol 12, Iss 17, p 2166 (2023)
The PKD1 gene, encoding protein polycystin-1 (PC1), is responsible for 85% of cases of autosomal dominant polycystic kidney disease (ADPKD). PC1 has been shown to be present in urinary exosome−like vesicles (PKD−ELVs) and lowered in individuals w
Externí odkaz:
https://doaj.org/article/cb0efb4fcbe4484790ed4e7ad2759ca2
Autor:
Tarak Srivastava, Trupti Joshi, Daniel P. Heruth, Mohammad H. Rezaiekhaligh, Robert E. Garola, Jianping Zhou, Varun C. Boinpelly, Mohammed Farhan Ali, Uri S. Alon, Madhulika Sharma, Gregory B. Vanden Heuvel, Pramod Mahajan, Lakshmi Priya, Yuexu Jiang, Ellen T. McCarthy, Virginia J. Savin, Ram Sharma, Mukut Sharma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Systemic inflammation in pregnant obese women is associated with 1.5- to 2-fold increase in serum Interleukin-6 (IL-6) and newborns with lower kidney/body weight ratio but the role of IL-6 in increased susceptibility to chronic kidney (CKD)
Externí odkaz:
https://doaj.org/article/eba3b1af72d249d7980f6ba1dad3729b
Publikováno v:
Data in Brief, Vol 35, Iss , Pp 106873- (2021)
The Notch signaling pathway is an important conserved pathway for normal homeostasis during development. However, targeted deletion of Notch4 (Notch4d1) or Notch3 (Notch3d1) in mice is not lethal. In fact, both Notch4d1 and Notch3d1 mice develop norm
Externí odkaz:
https://doaj.org/article/0475282d66d44af0864b1dfa75b7c5fd
Autor:
Priyanka S. Radadiya, Mackenzie M. Thornton, Rajni V. Puri, Sireesha Yerrathota, Johnny Dinh-Phan, Brenda Magenheimer, Dharmalingam Subramaniam, Pamela V. Tran, Hao Zhu, Subhashini Bolisetty, James P. Calvet, Darren P. Wallace, Madhulika Sharma
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Despite the recent launch of tolvaptan, the search for safer polycystic kidney disease (PKD) drugs continues. Ciclopirox (CPX) or its olamine salt (CPX-O) is contained in a number of commercially available antifungal agents. CPX is also reported to p
Externí odkaz:
https://doaj.org/article/6e7056f708454bdc9cd717dfd744b149
Autor:
Madhulika Sharma, Pranab K. Mohapatra
Publikováno v:
Materials Today: Proceedings. 78:907-910
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea4a01a188e8a10f1aec87bafe0a4a6
https://doi.org/10.1016/j.matpr.2022.12.264
https://doi.org/10.1016/j.matpr.2022.12.264
Autor:
V. Praveen Chakravarthi, Sireesha Yerrathota, Priyanka Radadiya, Clark Bloomer, Sumedha Gunewardhana, Madhulika Sharma
Publikováno v:
Data in Brief, Vol 30, Iss , Pp 105562- (2020)
Tg26 mice are robust models of human immunodeficiency virus 1 associated nephropathy (HIVAN). These mice are useful for HIVAN pathology analysis, and recent studies suggest that the Tg26 mouse model is an excellent model of other chronic kidney disea
Externí odkaz:
https://doaj.org/article/fde61db2aecf42378b0b23290eb5fc89
Autor:
Rajni Vaid Puri, Sireesha Yerrathota, Trisha Home, Jessica Y. Idowu, V. Praveen Chakravarthi, Christopher J. Ward, Pravin C. Singhal, Gregory B. Vanden Heuvel, Timothy A. Fields, Madhulika Sharma
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 12 (2019)
Notch pathway activation plays a central role in the pathogenesis of many glomerular diseases. We have previously shown that Notch4 expression was upregulated in various renal cells in human immunodeficiency virus (HIV)-associated nephropathy (HIVAN)
Externí odkaz:
https://doaj.org/article/a544e1427d1144e49e29e1d352cfedb9
Autor:
Wei Wang, Luciane M. Silva, Henry H. Wang, Matthew A. Kavanaugh, Tana S. Pottorf, Bailey A. Allard, Damon T. Jacobs, Ruochen Dong, Joseph T. Cornelius, Aakriti Chaturvedi, Katherine I. Swenson-Fields, Timothy A. Fields, Michele T. Pritchard, Madhulika Sharma, Chad Slawson, Darren P. Wallace, James P. Calvet, Pamela V. Tran
Publikováno v:
Kidney International. 102:577-591
Primary cilia are sensory organelles built and maintained by intraflagellar transport (IFT) multiprotein complexes. Deletion of several IFT-B genes attenuates polycystic kidney disease (PKD) severity in juvenile and adult autosomal dominant polycysti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0baa3ea40332105b7821affeac5d51f9
https://doi.org/10.1016/j.kint.2022.04.034
https://doi.org/10.1016/j.kint.2022.04.034
Autor:
Manila Salaria, Sunit Singhi, Pratibha Singhi, Madhulika Sharma, Navdeep Mangat, Tanvi Bhatia, Ronny Wickstrom, Ritu Aggarwal
Publikováno v:
Inflammation Research. 71:513-520
Pediatric meningitis is characterized by a colossal inflammatory response to the pathogen in the central nervous system (CNS). This unabated inflammatory response persists even after the removal of the pathogen by antibiotics/steroids causing collate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e299c381c3bacd2e66a6a400ec0c495e
https://doi.org/10.1007/s00011-022-01562-6
https://doi.org/10.1007/s00011-022-01562-6
Autor:
Richa Jalodia, Yaa Fosuah Abu, Mark Ryan Oppenheimer, Bridget Herlihy, Jingjing Meng, Irina Chupikova, Junyi Tao, Nillu Ghosh, Rajib Kumar Dutta, Udhghatri Kolli, Yan Yan, Eridania Valdes, Madhulika Sharma, Umakant Sharma, Shamsudheen Moidunny, Sabita Roy
Publikováno v:
J Neuroimmune Pharmacol
Opioid use disorder (OUD) is defined as the chronic use or misuse of prescribed or illicitly obtained opioids and is characterized by clinically significant impairment. The etiology of OUD is multifactorial as it is influenced by genetics, environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c107149b61ff0df6b084c2864b4a6ea
https://doi.org/10.1007/s11481-021-10046-z
https://doi.org/10.1007/s11481-021-10046-z