Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Madhulata Kumari"'
Autor:
Madhulata, Kumari, Naidu, Subbarao
Publikováno v:
Future medicinal chemistry. 14(21)
bBackground:/bIn the recent COVID-19 pandemic, SARS-CoV-2 infection spread worldwide. The 3C-like protease (3CLpro) is a promising drug target for SARS-CoV-2.bResults:/bWe constructed a deep learning-based convolutional neural network-quantitative st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::615fdf542e76cb4ac4df6851288cef55
https://pubmed.ncbi.nlm.nih.gov/36177879
https://pubmed.ncbi.nlm.nih.gov/36177879
Autor:
Madhulata Kumari, Naidu Subbarao
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:8185-8196
Current therapeutic strategies for several diseases, including Mycobacterium tuberculosis infection, have evolved from an initial single-target treatment to a multitarget one. A multitarget antitubercular drugs targeting different mycobacterial prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f124c813f5e3056080c41912b01ed206
https://doi.org/10.1080/07391102.2021.1908913
https://doi.org/10.1080/07391102.2021.1908913
Autor:
Madhulata Kumari, Naidu Subbarao
Publikováno v:
Future medicinal chemistry. 14(10)
Background: Marburg virus (MARV) is a sporadic outbreak of a zoonotic disease that causes lethal hemorrhagic fever in humans. We propose a deep learning model with resampling techniques and predict the inhibitory activity of MARV from unknown compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34e766ea4b696c52d6d16871cc3008d
https://pubmed.ncbi.nlm.nih.gov/35393862
https://pubmed.ncbi.nlm.nih.gov/35393862
Publikováno v:
Future Medicinal Chemistry. 12:147-159
Aim: We applied genetic programming approaches to understand the impact of descriptors on inhibitory effects of serine protease inhibitors of Mycobacterium tuberculosis ( Mtb) and the discovery of new inhibitors as drug candidates. Materials & method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cc100f62642d99b6e853f2c373f6aa6
https://doi.org/10.4155/fmc-2018-0560
https://doi.org/10.4155/fmc-2018-0560
Autor:
Madhulata Kumari, Naidu Subbarao
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:5062-5080
Glutamine synthetase (GS) of Mycobacterium tuberculosis (Mtb) is an essential enzyme which is involved in nitrogen metabolism and cell wall synthesis. It is involved in the inhibition of phagosome-lysosome fusion by preventing acidification. Targetin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35645c96f80b9f7367ab4ec31aa502df
https://doi.org/10.1080/07391102.2019.1695670
https://doi.org/10.1080/07391102.2019.1695670
Nature provides an infinite variety of plant species which includes number of neglected and underutilized crops that have been pushed into forgetfulness by the predominant ‘major’ cereals. Millets and pseudo-cereals belong to such category having
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::433f7031eaafe55d2518913c294b7284
https://doi.org/10.1016/b978-0-12-820089-6.00004-5
https://doi.org/10.1016/b978-0-12-820089-6.00004-5
Autor:
Aparna Agarwal, Supriya Babasaheb Aglawe, null Anuradha, Lalit Arya, Rahul Chandora, Ajay Kumar Chandra, B.S. Chethana, T.M. Dinesh, K.N. Ganapathy, K. Hariprasanna, A.K. Jain, D.C. Joshi, R.P. Joshi, S. Sanjeev Krishna, Madhulata Kumari, Nikhil Malhotra, N.G. Malleshi, R.P. Meena, A. Nagaraja, Sri Devi Nune, V. Ramya, B. Dayakar Rao, A.B. Narayana Reddy, Y.A. Nanja Reddy, Y.N. Priya Reddy, Harpreet Kaur Saini, Babita Sharma, Krishan Datt Sharma, Mamta Singh, Mohar Singh, Monika Singh, Salej Sood, L.S. Suma, Apoorv Tiwari, Vilas A. Tonapi, Manjusha Verma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a261c38928fbd57736e8606d88c528
https://doi.org/10.1016/b978-0-12-820089-6.09992-4
https://doi.org/10.1016/b978-0-12-820089-6.09992-4
Multi-targeting enzyme approaches are considered to be the most significant in suppressing pathogen growth and disease control for MDR and XDR-resistant Mycobacterium tuberculosis. The multiple Mur enzymes involved in peptidoglycan biosynthesis play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f8c5ada3f8eefa2e4ac5fb07303319
Publikováno v:
Bioinformation
Non-small cell lung cancer (NSCLC) is the most dominating and lethal type of lung cancer triggering more than 1.3 million deaths per year. The most effective line of treatment against NSCLC is to target epidermal growth factor receptor (EGFR) activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4283f08a303e20fd6be878c52f34f0
https://doi.org/10.6026/97320630012311
https://doi.org/10.6026/97320630012311