Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Madhu Sudhana Saddala"'
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30425- (2024)
Externí odkaz:
https://doaj.org/article/f5c927dc9c1249899cbe1c4034aff746
Autor:
Anton Lennikov, Menglu Yang, Karen Chang, Li Pan, Madhu Sudhana Saddala, Cherin Lee, Ajay Ashok, Kin-Sang Cho, Tor Paaske Utheim, Dong Feng Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Non-invasive electric stimulation (ES) employing a low-intensity electric current presents a potential therapeutic modality that can be applied for treating retinal and brain neurodegenerative disorders. As neurons are known to respond directly to ES
Externí odkaz:
https://doaj.org/article/70646beaab5e47798f1fcb84916b8621
Autor:
Madhu Sudhana Saddala, Anton Lennikov, Anthony Mukwaya, Yan Yang, Michael A. Hill, Neil Lagali, Hu Huang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-23 (2020)
Abstract Background The ways in which microglia activate and promote neovascularization (NV) are not fully understood. Recent in vivo evidence supports the theory that calcium is required for the transition of microglia from a surveillance state to a
Externí odkaz:
https://doaj.org/article/56b1e82bcadb4aa19f5a61223caf73ae
Publikováno v:
Journal of Integrative Agriculture, Vol 19, Iss 3, Pp 735-747 (2020)
Xanthomonas oryzae pv. oryzae (Xoo) is an important rice pathogen. This is a vascular pathogen entering the plant via the hydathodes causing rice bacterial blight. It has been known that most regulation of pathogenicity factor F (RpfF) genes in Xanth
Externí odkaz:
https://doaj.org/article/fd0de2134c344472b789f66760a2c467
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Retinal degenerative diseases affect millions of people and represent the leading cause of vision loss around the world. Retinal degeneration has been attributed to a wide variety of causes, such as disruption of genes involved in
Externí odkaz:
https://doaj.org/article/484a6814d19c478b911a452e9dbdb678
Autor:
Madhu Sudhana Saddala, Hu Huang
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Tumor necrosis factor α (TNFα) is a multifunctional cytokine with a potent pro-inflammatory effect. It is a validated therapeutic target molecule for several disorders related to autoimmunity and inflammation. TNFα–TNF recept
Externí odkaz:
https://doaj.org/article/56b4f417c1e444a4877b9f303284c08f
Publikováno v:
Human Genomics, Vol 13, Iss 1, Pp 1-14 (2019)
Abstract Background Age-related macular degeneration (AMD) is the most common, progressive, and polygenic cause of irreversible visual impairment in the world. The molecular pathogenesis of the primary events of AMD is poorly understood. We have inve
Externí odkaz:
https://doaj.org/article/9166ea592927457c944d46b758831510
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105915- (2020)
The CXCR5 (C-X-C motif chemokine receptor 5) is chemokine transmembrane receptor, acting via its ligand CXCL13 and plays a crucial role in controlling the trafficking of inflammatory cells into and from the sub-retinal space, which contributes to the
Externí odkaz:
https://doaj.org/article/b74ddaca82674404aaafaea407037cb4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Previous research has shown that CXCR5−/− mice develop retinal degeneration (RD) with age, a characteristic related to age macular degeneration (AMD). RD in these mice is not well-understood, and in this study, we sought to characterize further t
Externí odkaz:
https://doaj.org/article/9b084f7f199e49ae91a833fe03ab813e
Publikováno v:
Biomedicines, Vol 8, Iss 6, p 147 (2020)
Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in the elderly population. In our previous studies, we found that deficiency of CXCR5 causes AMD-like pathological phenotypes in mice, characterized by abnormal
Externí odkaz:
https://doaj.org/article/cf90f4d04d9e43558c883e027c00c3d3