Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Madhu Emmadi"'
Autor:
Paulina Kaplonek, Ling Yao, Katrin Reppe, Franziska Voß, Thomas Kohler, Friederike Ebner, Alexander Schäfer, Ulrike Blohm, Patricia Priegue, Maria Bräutigam, Claney L. Pereira, Sharavathi G. Parameswarappa, Madhu Emmadi, Petra Ménová, Martin Witzenrath, Sven Hammerschmidt, Susanne Hartmann, Leif E. Sander, Peter H. Seeberger
Publikováno v:
Vaccine
bioRxiv
bioRxiv
Streptococcus pneumoniae (S. pneumoniae) infections are the leading cause of child mortality globally. Current vaccines fail to induce a protective immune response towards a conserved part of the pathogen, resulting in new serotypes causing disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c7b2c9ac495244c7d58e1509e1a374
https://doi.org/10.1016/j.vaccine.2021.12.068
https://doi.org/10.1016/j.vaccine.2021.12.068
Autor:
P. Priegue, Susanne Hartmann, Claney L. Pereira, Martin Witzenrath, Sven Hammerschmidt, Thomas P. Kohler, A. Schaefer, Petra Ménová, P. M. Kaplonek, Leif E. Sander, Sharavathi Guddehalli Parameswarappa, F. M. Voss, Madhu Emmadi, Katrin Reppe, L. Yao, Peter H. Seeberger, Friederike Ebner, Maria Bräutigam, Ulrike Blohm
Streptococcus pneumoniaeinfections are the leading cause of child mortality globally. Current vaccines fail to induce a protective immune response towards a conserved part of the pathogen, resulting in new serotypes causing disease. Therefore, new va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68352daff7d1c0758176d195062b5be3
https://doi.org/10.1101/2021.07.29.454378
https://doi.org/10.1101/2021.07.29.454378
Publikováno v:
European Journal of Organic Chemistry. 2018:3230-3235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b452cd75fd70c180db502e97eda3991b
https://doi.org/10.1002/ejoc.201800209
https://doi.org/10.1002/ejoc.201800209
Autor:
Sandra-Maria Wienhold, Lennart Lykke, Katrin Reppe, Martin Witzenrath, Peter H. Seeberger, Madhu Emmadi, Marilda P. Lisboa, Claney L. Pereira, Sharavathi Guddehalli Parameswarappa, Naeem Khan
Publikováno v:
Journal of the American Chemical Society. 139:14783-14791
Invasive pneumococcal diseases (IPDs) remain the leading cause of vaccine-preventable childhood death, even though highly effective pneumococcal conjugate vaccines (PCVs) are used in national immunization programs in many developing countries. Licens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2497493f094dca752b0a6609ecaa4660
https://doi.org/10.1021/jacs.7b07836
https://doi.org/10.1021/jacs.7b07836
Autor:
Suvarn S. Kulkarni, Madhu Emmadi
Publikováno v:
The Journal of organic chemistry. 83(23)
Lipopolysaccharides (LPSs) play key roles in humoral immunity. Recently, the LPS structure of the Psychrobacter cryohalolentis K5T strain was reported. Due to the presence of unnatural amino sugars and branched linkages, its structure is unique. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25948fdc5507461ac9bbe8100d6b0dc
https://pubmed.ncbi.nlm.nih.gov/30388010
https://pubmed.ncbi.nlm.nih.gov/30388010
Autor:
Fei-Fei Xu, Katrin Reppe, Benjamin Schumann, Martin Witzenrath, Sharavathi Guddehalli Parameswarappa, Paulina Kaplonek, Claney L. Pereira, Peter H. Seeberger, Adam D. J. Calow, Naeem Khan, Madhu Emmadi, Marilda P. Lisboa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Streptococcus pneumoniae remains a deadly disease in small children and the elderly even though conjugate and polysaccharide vaccines based on isolated capsular polysaccharides (CPS) are successful. The most common serotypes that cause infection are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e169280462496e9923830fc4e86876
https://hdl.handle.net/21.11116/0000-0002-C08E-521.11116/0000-0002-C090-1
https://hdl.handle.net/21.11116/0000-0002-C08E-521.11116/0000-0002-C090-1
Autor:
Emily L. Clark, Madhu Emmadi, Suvarn S. Kulkarni, Danielle H. Dube, Katharine L. Krupp, Ananda Rao Podilapu, Jennifer D. Helble
Bacterial glycans contain rare, exclusively bacterial monosaccharides that are frequently linked to pathogenesis and essentially absent from human cells. Therefore, bacterial glycans are intriguing molecular targets. However, systematic discovery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c618f8fbaf88d349baf543fff1e64f4
https://europepmc.org/articles/PMC5161589/
https://europepmc.org/articles/PMC5161589/
Publikováno v:
IndraStra Global.
The first total synthesis of the alpha-L-serine linked consensus disaccharide of Neisseria gonorrhoeae and Neisseria meningitidis was carried out in six linear steps, with 20.6% overall yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff257cc41c79a2e046d7a49489488e9
http://dspace.library.iitb.ac.in/jspui/handle/100/17384
http://dspace.library.iitb.ac.in/jspui/handle/100/17384
Autor:
Madhu Emmadi, Suvarn S. Kulkarni
Publikováno v:
ChemInform. 45
Covering: 1964 to 2013 Bacteria have unusual glycans on their surfaces which distinguish them from the host cells. These unique structures offer avenues for targeting bacteria with specific therapeutics and vaccine. However, these rare sugars are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f5b3d57bf2569bc9625102fc528c0b1
https://doi.org/10.1002/chin.201432270
https://doi.org/10.1002/chin.201432270
Autor:
Madhu Emmadi, Suvarn S. Kulkarni
Publikováno v:
Natural product reports. 31(7)
Covering: 1964 to 2013 Bacteria have unusual glycans on their surfaces which distinguish them from the host cells. These unique structures offer avenues for targeting bacteria with specific therapeutics and vaccine. However, these rare sugars are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd738801e5220734b214be898e98ea4
https://pubmed.ncbi.nlm.nih.gov/24700208
https://pubmed.ncbi.nlm.nih.gov/24700208