Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Madhu B. Garg"'
Publikováno v:
BioTechniques, Vol 68, Iss 1, Pp 28-34 (2020)
Southern blotting of DNA terminal restriction fragment lengths is the gold standard for measuring mean telomere length. Analysis of the final image is a crucial step in this process, however, current techniques are cumbersome and prone to error. Here
Externí odkaz:
https://doaj.org/article/8b9864e6bb624e0a973115c788c2b985
Publikováno v:
BioTechniques. 68(1)
Southern blotting of DNA terminal restriction fragment lengths is the gold standard for measuring mean telomere length. Analysis of the final image is a crucial step in this process, however, current techniques are cumbersome and prone to error. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1190081939f8b13adc010186ca908cdf
https://pubmed.ncbi.nlm.nih.gov/31825239
https://pubmed.ncbi.nlm.nih.gov/31825239
Publikováno v:
Journal of Cancer Therapy. :230-236
Background: The NPxY motif common to all β integrin cytoplasmic domains forms part of a canonical recognition sequence for phosphotyrosine-binding domains which are protein modules present in a wide variety of signaling and cytoskeletal proteins. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688477d66661971615d8461786225c5e
https://doi.org/10.4236/jct.2012.34033
https://doi.org/10.4236/jct.2012.34033
Publikováno v:
Journal of Chromatography B. 879:2201-2205
Mitotane (o,p'-DDD or (1,1-dichloro-2-[o-chlorophenyl]-2-[p-chlorophenyl]ethane, DDD) is the drug of choice for non-resectable and metastatic adrenocortical carcinomas (ACC). Measurement of mitotane and metabolites, o,p'-DDE (1,1-dichloro-2-[p-chloro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14ab6f1eeff5b09e51a0c1628d31fdf
https://doi.org/10.1016/j.jchromb.2011.06.001
https://doi.org/10.1016/j.jchromb.2011.06.001
Publikováno v:
Journal of Cancer Therapy. :295-301
Background: It is known that active Src kinase promotes survival of ovarian cancer cell lines and inhibition of c-Src has been shown to restore sensitivity of drug-resistant human ovarian cancer cells to cisplatin. In this study we examined the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00276c7770ea2072f36fe4de093aa0db
https://doi.org/10.4236/jct.2011.23039
https://doi.org/10.4236/jct.2011.23039
Publikováno v:
International Journal of Cancer. 120:1930-1934
Thymidylate synthase (TS) activity is an important determinant of response to chemotherapy with fluoropyrimidine prodrugs and its expression is largely determined by the number of functional upstream stimulatory factor (USF) E-box consensus elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2acc219a02ebfdd376c6ac3dc5156c4
https://doi.org/10.1002/ijc.22568
https://doi.org/10.1002/ijc.22568
Autor:
David Farlow, Graham J. Mann, Michael T. Collins, Mark Wong, Stephen P. Ackland, Janelle M. Hoskins, Scott R. Evans, Christine L. Clarke, Andrew J. McLachlan, Laurent P. Rivory, Rosemary L. Balleine, Elaine Y. L. Blair, Howard Gurney, Madhu B. Garg
Publikováno v:
Journal of Clinical Oncology. 24:2448-2455
Purpose Marked interindividual variation in drug disposition and toxicity pose an ongoing challenge to chemotherapy dosage individualization. The aim of this study was to evaluate pretreatment clinical features, genotype and functional indicators of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39bf195a814301c877eafab05c266c7b
https://doi.org/10.1200/jco.2005.02.1295
https://doi.org/10.1200/jco.2005.02.1295
Autor:
Suzanne Parker, Rebecca Jokela, Philip Clingan, Morteza Aghmesheh, Madhu B. Garg, Marie Ranson, Daniel Brungs, Stephen P. Ackland, Ali Tafreshi, Paul de Souza, Richard David Ranson
Publikováno v:
Journal of Clinical Oncology. 35:2530-2530
2530 Background: Simultaneous administration of 5-fluorouracil (5FU) and leucovorin (LV) is generally not feasible as 5FU and LV are chemically incompatible (CaPO4 crystals), so the maximum possible interaction for benefit is not achieved. Deflexifol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::846aa65439744295b5dea91bbb998cdb
https://doi.org/10.1200/jco.2017.35.15_suppl.2530
https://doi.org/10.1200/jco.2017.35.15_suppl.2530
Autor:
Philip Clingan, Stephen P. Ackland, Marie Ranson, Ali Tafreshi, Daniel Brungs, Suzanne Parker, Rebecca Jokela, Paul de Souza, Morteza Aghmesheh, Madhu B. Garg
Publikováno v:
Journal of Clinical Oncology. 35:TPS812-TPS812
TPS812 Background: 5FU is a commonly used anti-cancer agent first synthesized in 1957, and is now most commonly used in combination with FA, which enhances its clinical activity. Physical incompatibilities between 5FU and LV necessitate the infusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea43a26f829b985b30ec2c3c33a7d24
https://doi.org/10.1200/jco.2017.35.4_suppl.tps812
https://doi.org/10.1200/jco.2017.35.4_suppl.tps812
Autor:
Madhu B. Garg, Stephen P. Ackland
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 748:383-388
Several methods for quantification of docetaxel have been described mainly using HPLC. We have developed a new isocratic HPLC method that is as sensitive and simpler than previous methods, and applicable to use in clinical pharmacokinetic analysis. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7baef96469427ae36a1fce5979f7cb
https://doi.org/10.1016/s0378-4347(00)00356-x
https://doi.org/10.1016/s0378-4347(00)00356-x