Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Madhobi Sen"'
Autor:
Zhe Zhang, Xin Wang, Feda H. Hamdan, Anna Likhobabina, Shilpa Patil, Lena Aperdannier, Madhobi Sen, Jacobe Traub, Albrecht Neesse, André Fischer, Argyris Papantonis, Shiv K. Singh, Volker Ellenrieder, Steven A. Johnsen, Elisabeth Hessmann
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1219-1246 (2023)
Background & Aims: Loss of AT-rich interactive domain-containing protein 1A (ARID1A) fosters acinar-to-ductal metaplasia (ADM) and pancreatic carcinogenesis by down-regulating transcription programs controlling acinar cell identity. However, how ARID
Externí odkaz:
https://doaj.org/article/eb30d11bebe1451192c01dfee4b0bc4b
Autor:
Iga K. Mieczkowska, Garyfallia Pantelaiou-Prokaki, Evangelos Prokakis, Geske E. Schmidt, Lukas C. Müller-Kirschbaum, Marcel Werner, Madhobi Sen, Taras Velychko, Katharina Jannasch, Christian Dullin, Joanna Napp, Klaus Pantel, Harriet Wikman, Maria Wiese, Christof M. Kramm, Frauke Alves, Florian Wegwitz
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Abstract Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development of targeted therapies have greatly improved the survival rate of BC patients. However, the ba
Externí odkaz:
https://doaj.org/article/20c0c3f49a9e491b86d9b16315f3a86d
Autor:
Garyfallia Pantelaiou-Prokaki, Taras Velychko, Maria Wiese, Christian Dullin, Iga K Mieczkowska, Florian Wegwitz, Katharina Jannasch, Geske Schmidt, Joanna Napp, Klaus Pantel, Frauke Alves, Harriet Wikman, Marcel Werner, Madhobi Sen, Lukas C Müller-Kirschbaum, Evangelos Prokakis, Christof M. Kramm
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development of targeted therapies have greatly improved the survival rate of BC patients. However, the basal-like
Autor:
Feda H. Hamdan, Steven A. Johnsen, Elisabeth Hessmann, Madhobi Sen, Jacobe Rapp, Robyn Laura Kosinsky, Florian Wegwitz, Philipp Strӧbel, Jessica Eggert, Ana P. Kutschat, Jochen Gaedcke, Xin Wang, Fereshteh S. Younesi, Argyris Papantonis, Marian Grade
Publikováno v:
Clinical Epigenetics
Background ARID1A (AT-rich interactive domain-containing protein 1A) is a subunit of the BAF chromatin remodeling complex and plays roles in transcriptional regulation and DNA damage response. Mutations in ARID1A that lead to inactivation or loss of
Autor:
Madhobi Sen, Wang, Xin, Feda Hamdan, Jacobe Rapp, Eggert, Jessica, Kosinsky, Robyn, Wegwitz, Florian, Kutschat, Ana, Younesi, Fereshteh, Gaedcke, Jochen, Grade, Marian, Hessmann, Elisabeth, Papantonis, Argyris, StrÓ§Bel, Philipp, Johnsen, Steven
Figure S1. Expression of BAF complex subunits in the four cell lines used in this study (a). Mutual exclusivity of ARID1A and KRAS (all and specifically at residues G12 and G13) mutations in the colorectal adenocarcinoma patient cohort from the TCGA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860a804f7a61ba26468645695d403193
Autor:
Madhobi Sen, Wang, Xin, Feda Hamdan, Jacobe Rapp, Eggert, Jessica, Kosinsky, Robyn, Wegwitz, Florian, Kutschat, Ana, Younesi, Fereshteh, Gaedcke, Jochen, Grade, Marian, Hessmann, Elisabeth, Papantonis, Argyris, StrÓ§Bel, Philipp, Johnsen, Steven
Supplementary tables. This file contains supplementary Tables S1â S4. (DOCX 31 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7207f5418b8530f216b119a045dbba69
Autor:
Vivek Kumar, Mishra, Florian, Wegwitz, Robyn Laura, Kosinsky, Madhobi, Sen, Roland, Baumgartner, Tanja, Wulff, Jens T, Siveke, Hans-Ulrich, Schildhaus, Zeynab, Najafova, Vijayalakshmi, Kari, Hella, Kohlhof, Elisabeth, Hessmann, Steven A, Johnsen
Publikováno v:
Nucleic Acids Research
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a particularly dismal prognosis. Histone deacetylases (HDAC) are epigenetic modulators whose activity is frequently deregulated in various cancers including PDAC. In particula
Autor:
Marie C. Hasselluhn, Jessica Spitalieri, Waltraut Kopp, Christin Kellner, Shiv K. Singh, Lena Aperdannier, Volker Ellenrieder, Steven A. Johnsen, Zhe Zhang, Madhobi Sen, Elisabeth Hessmann
Publikováno v:
Pancreatology. 18:S149-S150
Autor:
Zhe Zhang, Waltraut Kopp, Hanibal Bohnenberger, Xin Wang, Feda Hamdan, Madhobi Sen, Lena Aperdannier, Steven A. Johnsen, Elisabeth Hessmann
Publikováno v:
Pancreatology. 19:S159
Publikováno v:
Cancer Research. 78:1472-1472
Recent genome- and exome-wide sequencing studies have revealed a close association between the epigenome and the pathogenesis of cancer. Not only were chromatin regulators found to be commonly mutated in a wide range of cancers, but a class of these