Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Madhavi Krishnan"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Inferring the 3D structure and conformation of disordered biomolecules, e.g., single stranded nucleic acids (ssNAs), remains challenging due to their conformational heterogeneity in solution. Here, we use escape-time electrometry (ETe) to me
Externí odkaz:
https://doaj.org/article/ef47300a8af94ad792777c9514c87022
Wide-field optical imaging of electrical charge and chemical reactions at the solid-liquid interface
Publikováno v:
Proceedings of the National Academy of Sciences USA
From molecules and particles to macroscopic surfaces immersed in fluids, chemical reactions often endow interfaces with electrical charge which in turn governs surface interactions and interfacial phenomena. The ability to measure the electrical prop
Publikováno v:
Macromolecules. 55(14)
A DNA molecule is highly electrically charged in solution. The electrical potential at the molecular surface is known to vary strongly with the local geometry of the double helix and plays a pivotal role in DNA-protein interactions. Further out from
Publikováno v:
The Journal of Physical Chemistry B, 126 (25)
Molecular dynamics studies have demonstrated that molecular water at an interface, with either a gas or a solid, displays anisotropic orientational behavior in contrast to its bulk counterpart. This effect has been recently implicated in the like-cha
We consider the long-standing like-charge attraction problem, wherein under certain conditions, similarly charged spheres suspended in aqueous electrolyte have been observed to display a minimum in their interaction potential, contrary to the intuiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123ec3d4822fe10369c041bbd1767dcc
https://doi.org/10.1021/acs.langmuir.1c02801
https://doi.org/10.1021/acs.langmuir.1c02801
Publikováno v:
Current Opinion in Chemical Biology
Trapping of a single molecule in the fluid phase was realized decades following developments in the gas-phase, because in some ways the solution phase posed a greater challenge. The key issues have since been addressed by several different means; tec
Autor:
Madhavi Krishnan, Francesca Ruggeri
Publikováno v:
Nano letters. 18(6)
We demonstrate the ability to confine a single molecule in solution by spatial modulation of its local configurational entropy. Previously we established electrostatic trapping of a charged macromolecule by geometric tailoring of a repulsive electric
Autor:
Madhavi Krishnan, Francesca Ruggeri
Escape-time electrometry is a recently developed experimental technique that offers the ability to measure the effective electrical charge of a single biomolecule in solution with sub-elementary charge precision. The approach relies on measuring the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801a2a2469d4c37da68b061a536a9480
https://doi.org/10.5167/uzh-143926
https://doi.org/10.5167/uzh-143926
Publikováno v:
Nature Nanotechnology. 10:886-891
The binary switch is a basic component of digital information. From phase-change alloys to nanomechanical beams, molecules and atoms, new strategies for controlled bistability hold great interest for emerging technologies. We present a generic method
Autor:
Madhavi Krishnan
Publikováno v:
The Journal of Chemical Physics
We present a model for calculating the net and effective electrical charge of globular macromolecules and linear polyelectrolytes such as proteins and DNA, given the concentration of monovalent salt and pH in solution. The calculation is based on a n