Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Madhavi Bathina"'
Autor:
Ken Batai, Zuxi Cui, Amit Arora, Ebony Shah-Williams, Wenndy Hernandez, Maria Ruden, Courtney M P Hollowell, Stanley E Hooker, Madhavi Bathina, Adam B Murphy, Carolina Bonilla, Rick A Kittles
Publikováno v:
PLoS Genetics, Vol 17, Iss 2, p e1009319 (2021)
A recent genome-wide association study (GWAS) in African descent populations identified novel loci associated with skin pigmentation. However, how genomic variations affect skin pigmentation and how these skin pigmentation gene variants affect serum
Externí odkaz:
https://doaj.org/article/b855969a0e24407db55249e7bec2f497
Autor:
Lindsey K. Sablatura, Kristin M. Bircsak, Peter Shepherd, Madhavi Bathina, Karla Queiroz, Mary C. Farach‐Carson, Rick A. Kittles, Pamela E. Constantinou, Anthony Saleh, Nora M. Navone, Daniel A. Harrington
Publikováno v:
Advanced healthcare materials.
Many advanced cancer models, such as patient-derived xenografts (PDXs), offer significant benefits in their preservation of the native tumor's heterogeneity and susceptibility to treatments, but face significant barriers to use in their reliance on a
Autor:
Madhavi Bathina, Stanley Hooker, Ranjana Mitra, Leanne Woods-Burnham, K. Sean Kimbro, Rick A. Kittles, Stacy M. Lloyd, Larisa Nonn, Priyatham Gorjala
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Given the scarcity of cell lines from underrepresented populations, it is imperative that genetic ancestry for these cell lines is characterized. Consequences of cell line mischaracterization include squandered resources and publication r
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:D114-D114
BACKGROUND: African American (AA) men are disproportionately affected by both prostate cancer (PCa) and vitamin D deficiency compared with European American (EA) men. Vitamin D deficiency is linked to increased PCa aggressiveness and mortality. Infla
Autor:
Stacy M. Lloyd, Stanley Hooker, Rick A. Kittles, Kevin S. Kimbro, Ranjana Mitra, Madhavi Bathina, Priyatham Gorjala
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:B073-B073
Given the scarcity of human cell lines from under-represented populations available for study, it is crucial that these cell lines be accurately characterized regarding their genetic ancestry so findings can be properly contextualized. Mischaracteriz
Autor:
Rhonda M. Perciavalle, Madhavi Bathina, Kristen Bisanz, Brian Koss, Daniel P. Stewart, Joseph T. Opferman
Publikováno v:
Molecular and Cellular Biology. 30:3099-3110
Antiapoptotic myeloid cell leukemia 1 (MCL-1) is an essential modulator of survival during the development and maintenance of a variety of cell lineages. Its turnover, believed to be mediated by the ubiquitin-proteasome system, facilitates apoptosis
Autor:
Zaneta Nikolovska-Coleska, Xue Yang, Brian Koss, Anthony Letai, Amit Budhraja, Katherine Szarama, Michael H. Cardone, Jeremy Ryan, Madhavi Bathina, Joseph T. Opferman
Publikováno v:
Oncotarget
One of the hallmarks of cancer is a resistance to the induction of programmed cell death that is mediated by selection of cells with elevated expression of anti-apoptotic members of the BCL-2 family. To counter this resistance, new therapeutic agents
Autor:
Brian Koss, John D. Schuetz, Sharon Frase, Madhavi Bathina, John Lynch, Christopher R. Calabrese, Jerold E. Rehg, Joseph T. Opferman, Xi Wang
Publikováno v:
Genesdevelopment. 27(12)
MCL-1 is an essential BCL-2 family member that promotes the survival of multiple cellular lineages, but its role in cardiac muscle has remained unclear. Here, we report that cardiac-specific ablation of Mcl-1 results in a rapidly fatal, dilated cardi
Autor:
Richard J. Youle, Douglas R. Green, Sandra Milasta, Madhavi Bathina, Rhonda M. Perciavalle, Brian Koss, Jamshid Temirov, John D. Schuetz, Daniel P. Stewart, Stephane Pelletier, Megan M. Cleland, Joseph T. Opferman, John Lynch
MCL-1, an anti-apoptotic BCL-2 family member that is essential for the survival of multiple cell lineages, is also among the most highly amplified genes in cancer. Although MCL-1 is known to oppose cell death, precisely how it functions to promote su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f351f19193aa00e9bed65a0a57145
https://europepmc.org/articles/PMC3401947/
https://europepmc.org/articles/PMC3401947/
Publikováno v:
Cancer investigation. 26(9)
Advanced prostate cancer cells are typically hormone independent, resistant to apoptosis and do not respond to chemotherapeutic agents. The ability of methyl jasmonate (MJ) and cis-jasmone (CJ) to inhibit growth in hormone independent prostate cancer