Zobrazeno 1 - 10
of 325
pro vyhledávání: '"Madhav V Dhodapkar"'
Autor:
Martin Vogel, Muna Qayed, Shanmuganathan Chandrakasan, Sharmila Raghunandan, Melinda Pauly, William G Blum, Madhav V Dhodapkar, Mohamed Elkhalifa, Benjamin Watkins, Michelle Schoettler, Edwin Horwitz, Suhag Parikh, Kathryn Leung, Elyse Bryson, Laura Deeb, Jonathan L Kaufman, Diana Worthington-White, Adina Alazraki, Jordan M Schecter, Deepu Madduri, Carolyn C Jackson, Enrique Zudaire, Agne Taraseviciute-Morris, Alexander Babich, Tonia Nesheiwat, Nikoletta Lendvai, Lida Pacaud, Kirsten M Williams
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Plasmablastic lymphoma (PBL) is a rare subtype of aggressive large B-cell lymphoma, with a dismal prognosis despite aggressive therapies. New approaches are needed for those with refractory disease. PBL expresses antigens similar to multiple myeloma
Externí odkaz:
https://doaj.org/article/8d09210335ff4eafb1dab8feacb96d23
Autor:
Samuel A Danziger, Mark McConnell, Jake Gockley, Mary H Young, Adam Rosenthal, Frank Schmitz, David J Reiss, Phil Farmer, Daisy V Alapat, Amrit Singh, Cody Ashby, Michael Bauer, Yan Ren, Kelsie Smith, Suzana S Couto, Frits van Rhee, Faith Davies, Maurizio Zangari, Nathan Petty, Robert Z Orlowski, Madhav V Dhodapkar, Wilbert B Copeland, Brian Fox, Antje Hoering, Alison Fitch, Katie Newhall, Bart Barlogie, Matthew W B Trotter, Robert M Hershberg, Brian A Walker, Andrew P Dervan, Alexander V Ratushny, Gareth J Morgan
Publikováno v:
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
BackgroundThe tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, wh
Externí odkaz:
https://doaj.org/article/48a59d8f2fb64baa9b747522459ffea9
Autor:
Andres Chang, Jean L. Koff, Lilin Lai, Victor M. Orellana-Noia, Minal Surati, Alyssa M. K. Leal, Madison L. Ellis, Bushra Wali, Alberto Moreno, Susanne L. Linderman, Colin B. O’Leary, Pamela B. Allen, Michael C. Churnetski, Madhav V. Dhodapkar, Mehul S. Suthar, Jonathon B. Cohen, Rafi Ahmed
Publikováno v:
Blood Advances. 7:2459-2462
Autor:
Michael M. Boyiadzis, Madhav V. Dhodapkar, Renier J. Brentjens, James N. Kochenderfer, Sattva S. Neelapu, Marcela V. Maus, David L. Porter, David G. Maloney, Stephan A. Grupp, Crystal L. Mackall, Carl H. June, Michael R. Bishop
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Chimeric Antigen Receptor (CAR) T cell therapies – adoptive T cell therapies that have been genetically engineered for a new antigen-specificity - have displayed significant success in treating patients with hematologic malignancies, leadi
Externí odkaz:
https://doaj.org/article/5a568f9326c844da8f86b218c9098847
Autor:
Andres Chang, Akil Akhtar, Susanne L. Linderman, Lilin Lai, Victor M. Orellana-Noia, Rajesh Valanparambil, Hasan Ahmed, Veronika I. Zarnitsyna, Ashley A. McCook-Veal, Jeffrey M. Switchenko, Jean L. Koff, Kristie A. Blum, Amy A. Ayers, Colin B. O'Leary, Michael C. Churnetski, Shahana Sulaiman, Melissa Kives, Preston Sheng, Carl W. Davis, Ajay K. Nooka, Rustom Antia, Madhav V. Dhodapkar, Mehul S. Suthar, Jonathon B. Cohen, Rafi Ahmed
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(26)
PURPOSE Patients with non-Hodgkin lymphoma including chronic lymphocytic leukemia (NHL/CLL) are at higher risk of severe SARS-CoV-2 infection. We investigated vaccine-induced antibody responses in patients with NHL/CLL against the original SARS-CoV-2
Autor:
Andres Chang, Akil Akhtar, Lilin Lai, Victor M. Orellana-Noia, Susanne L. Linderman, Ashley A. McCook-Veal, Jeffrey M. Switchenko, Manpreet Saini, Rajesh M. Valanparambil, Kristie A. Blum, Pamela B. Allen, Mary Jo Lechowicz, Jason T. Romancik, Amy Ayers, Alyssa Leal, Colin B. O'Leary, Michael C. Churnetski, Katelin Baird, Melissa Kives, Jens Wrammert, Ajay K. Nooka, Jean L. Koff, Madhav V. Dhodapkar, Mehul S. Suthar, Jonathon B. Cohen, Rafi Ahmed
Publikováno v:
Cancer Research Communications. 2:1684-1692
Patients with non–Hodgkin lymphoma and chronic lymphocytic leukemia (NHL/CLL) elicit inadequate antibody responses after initial SARS-CoV-2 vaccination and remain at high risk of severe COVID-19 disease. We investigated IgG, IgA, and IgM responses
Autor:
Maryam I. Azeem, Ajay K. Nooka, Uma Shanmugasundaram, Narayanaiah Cheedarla, Sayalee Potdar, Renee Julia Manalo, Alberto Moreno, Jeffrey M. Switchenko, Suneethamma Cheedarla, Deon Bryant Doxie, Roman Radzievski, Madison Leigh Ellis, Kelly E. Manning, Bushra Wali, Rajesh M. Valanparambil, Kathryn T. Maples, Essence Baymon, Jonathan L. Kaufman, Craig C. Hofmeister, Nisha S. Joseph, Sagar Lonial, John D. Roback, Alessandro Sette, Rafi Ahmed, Mehul S. Suthar, Andrew S. Neish, Madhav V. Dhodapkar, Kavita M. Dhodapkar
Publikováno v:
Blood Cancer Discovery. 4:106-117
Patients with multiple myeloma (MM) mount suboptimal neutralizing antibodies (nAb) following 2 doses of SARS-CoV-2 mRNA vaccines. Currently, circulating SARS-CoV-2 variants of concern (VOC) carry the risk of breakthrough infections. We evaluated immu
Autor:
Shin-ichiro Fujii, Toyotaka Kawamata, Kanako Shimizu, Jun Nakabayashi, Satoru Yamasaki, Tomonori Iyoda, Jun Shinga, Hiroshi Nakazato, An Sanpei, Masami Kawamura, Shogo Ueda, Jan Dörrie, Svetlana Mojsov, Madhav V. Dhodapkar, Michihiro Hidaka, Masanori Nojima, Fumitaka Nagamura, Shigemi Yoshida, Toshio Goto, Arinobu Tojo
Publikováno v:
Molecular Therapy - Oncolytics. 27:315-332
Autor:
Rajesh M. Valanparambil, Jennifer Carlisle, Susanne L. Linderman, Akil Akthar, Ralph Linwood Millett, Lilin Lai, Andres Chang, Ashley A. McCook-Veal, Jeffrey Switchenko, Tahseen H. Nasti, Manpreet Saini, Andreas Wieland, Kelly E. Manning, Madison Ellis, Kathryn M. Moore, Stephanie L. Foster, Katharine Floyd, Meredith E. Davis-Gardner, Venkata-Viswanadh Edara, Mit Patel, Conor Steur, Ajay K. Nooka, Felicia Green, Margaret A. Johns, Fiona O'Brein, Uma Shanmugasundaram, Veronika I. Zarnitsyna, Hasan Ahmed, Lindsay E. Nyhoff, Grace Mantus, Michael Garett, Srilatha Edupuganti, Madhusmita Behra, Rustom Antia, Jens Wrammert, Mehul S. Suthar, Madhav V. Dhodapkar, Suresh Ramalingam, Rafi Ahmed
Publikováno v:
Journal of Clinical Oncology. 40:3808-3816
PURPOSE To examine COVID-19 mRNA vaccine–induced binding and neutralizing antibody responses in patients with non–small-cell lung cancer (NSCLC) to SARS-CoV-2 614D (wild type [WT]) strain and variants of concern after the primary 2-dose and boost
Autor:
Lijun Yao, Reyka G. Jayasinghe, Brian H. Lee, Swati S. Bhasin, William Pilcher, Deon Bryant Doxie, Edgar Gonzalez-Kozlova, Surendra Dasari, Mark A. Fiala, Yered Pita-Juarez, Michael Strausbauch, Geoffrey Kelly, Beena E. Thomas, Shaji K. Kumar, Hearn Jay Cho, Emilie Anderson, Michael C. Wendl, Travis Dawson, Darwin D'souza, Stephen T. Oh, Giulia Cheloni, Ying Li, John F. DiPersio, Adeeb H. Rahman, Kavita M. Dhodapkar, Seunghee Kim-Schulze, Ravi Vij, Ioannis S. Vlachos, Shaadi Mehr, Mark Hamilton, Daniel Auclair, Taxiarchis Kourelis, David Avigan, Madhav V. Dhodapkar, Sacha Gnjatic, Manoj K. Bhasin, Li Ding
Publikováno v:
Cancer Research Communications. 2:1255-1265
As part of the Multiple Myeloma Research Foundation (MMRF) immune atlas pilot project, we compared immune cells of multiple myeloma bone marrow samples from 18 patients assessed by single-cell RNA sequencing (scRNA-seq), mass cytometry (CyTOF), and c