Administration of a soluble ADPase, AZD3366, on top of ticagrelor confers additional cardioprotective benefits to that of ticagrelor alone

Autor: Laura Casaní, Madelyn Gutierrez, Soumaya Ben-Aicha, Gemma Vilahur, Antonio Hidalgo, O Fjellstrom, P Sutelman, Lina Badimon, Leif Carlsson, Monika Arzanauskaite

Publikováno v: European Heart Journal. 41

Background Preclinical and pilot human studies suggest platelet-independent cardioprotective effects of ticagrelor most likely due to its ability to block cellular uptake of adenosine. Adenosine is a potent endogenous protective molecule, concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efd4b58c2d3ee5321ed48e207c2985e6
https://doi.org/10.1093/ehjci/ehaa946.3772

3110Ticagrelor improves cardiac function and post-myocardial infarction healing: cardiac magnetic resonance imaging assessment of functional, anatomical and remodeling parameters

Autor: Lina Badimon, Gemma Vilahur, Laura Casaní, Madelyn Gutierrez, Soumaya Ben-Aicha, Alberto Hidalgo, Leif Carlsson, Antoni Capdevila, Guiomar Mendieta, Francesc Carreras, Guillem Pons-Lladó, Carmen Lambert

Publikováno v: European Heart Journal. 38

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fbab5c344f5d1c84c7fc2d378a926a4
https://doi.org/10.1093/eurheartj/ehx504.3110

Homozygosity of the autosomal dominant Alzheimer disease presenilin 1 E280A mutation

Autor: Sonia Moreno, Pierre N. Tariot, Madelyn Gutierrez, Jessica B. Langbaum, Shehnaaz Suliman, Carole Ho, Silvia Rios Romenets, G. Garcia, Kenneth S. Kosik, Lucia Madrigal, Eric M. Reiman, Francisco Lopera, Mary Luz Arcila, William Cho, Hugo Lopez, Liliana Lopez, Claudia Muñoz

Publikováno v: Neurology, vol 84, iss 2
Kosik, KS; Muñoz, C; Lopez, L; Arcila, ML; García, G; Madrigal, L; et al.(2014). Homozygosity of the autosomal dominant alzheimer disease presenilin 1 E280A mutation. Neurology, 84(2), 206-208. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/8mf346f1

We identified several families in Antioquia, Colombia, with early-onset Alzheimer disease (AD) due to the mendelian autosomal dominant inheritance of a PSEN1 E280A gene mutation. Extended family members were interviewed and parish baptism certificate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9a2b12d99f88c23530d2509cd41213
https://doi.org/10.1212/wnl.0000000000001130

P4‐269: Relationships between baseline biomarkers and subsequent cognitive decline in cognitively unimpaired PSEN1 E280A mutation carriers from the colombian kindred with autosomal dominant Alzheimer's disease

Autor: Pradeep Thiyyagura, Anne M. Fagan, Madelyn Gutierrez, Kewei Chen, Yakeel T. Quiroz, Gloria María Gallego García, Pierre N. Tariot, Hillary Protas, Claudia Muñoz, Margarita Giraldo, Victoria Tirado, Lina Velilla, Sehily Y. Jaimes, Reisa A. Sperling, Francisco Lopera, Aarti R. Shah, Eric M. Reiman, Marisol Londono, Auttawut Roontiva, Jessica B. Langbaum

Publikováno v: Alzheimer's & Dementia. 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f768a0a95470e5f08f63856f23fa0763
https://doi.org/10.1016/j.jalz.2015.08.098

P4–068: Pre‐symptomatic functional brain changes in PS1 E280A mutation carriers compared with other biomarkers: Pilot data from the Alzheimer's Prevention Initiative Biomarker project

Autor: Adam Fleisher, Kewei Chen, Yakeel Quiroz, null Laura Jakimovich, Madelyn Gutierrez, Jessica Langbaum, Auttawut Roontiva, Pradeep Thiyyagura, Ji Luo, Xiaofen Liu, Wendy Lee, Napatkamon Ayutyanont, Stephanie Parks, Claudia Munoz, Sonia Moreno, Natalia Acosta‐Baena, Margarita Giraldo, Pierre Tariot, Francisco Lopera, Eric Reiman

Publikováno v: Alzheimer's & Dementia. 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc53bd5cdae8b8ae1cb3c5507396c0a5
https://doi.org/10.1016/j.jalz.2013.05.1457