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pro vyhledávání: '"Madelyn Blake"'
Autor:
Madelyn Blake, Patrycja Puchalska, Felipe Kazmirczak, Jeffrey Blake, Ryan Moon, Thenappan Thenappan, Peter A. Crawford, Kurt W. Prins
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22227- (2023)
Background: Ketone bodies are pleotropic metabolites that play important roles in multiple biological processes ranging from bioenergetics to inflammation regulation via suppression of the NLRP3 inflammasome, and epigenetic modifications. Ketone bodi
Externí odkaz:
https://doaj.org/article/0ef249094f134365bc62e5bfac32154e
Autor:
Daphne M. Moutsoglou, Jasmine Tatah, Sasha Z. Prisco, Kurt W. Prins, Christopher Staley, Sharon Lopez, Madelyn Blake, Levi Teigen, Felipe Kazmirczak, E. Kenneth Weir, Amanda J. Kabage, Weihua Guan, Alexander Khoruts, Thenappan Thenappan
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:740-756
Inflammation drives pulmonary arterial hypertension (PAH). Gut dysbiosis causes immune dysregulation and systemic inflammation by altering circulating microbial metabolites; however, little is known about gut dysbiosis and microbial metabolites in PA