Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Madelon, Bracke"'
Autor:
Toine ten Broeke, Henk Honing, Arianne M. Brandsma, Shamir Jacobino, Jantine E. Bakema, Deon Kanters, Jan A. M. van der Linden, Madelon Bracke, Leo Koenderman, Jeanette H. W. Leusen
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
IgA binding to FcαRI (CD89) is rapidly enhanced by cytokine induced inside-out signaling. Dephosphorylation of serine 263 in the intracellular tail of FcαRI by PP2A and PI3K activation are instrumental in this process. To further investigate these
Externí odkaz:
https://doaj.org/article/2dbd0a8f24aa4fa4a4420d69382334a8
Autor:
Toine ten Broeke, Henk Honing, Arianne M. Brandsma, Shamir Jacobino, Jantine E. Bakema, Deon Kanters, Jan A. M. van der Linden, Madelon Bracke, Leo Koenderman, Jeanette H. W. Leusen
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 9. Frontiers Media S. A.
Frontiers in Immunology, Vol 9 (2019)
Frontiers in Immunology, 9. Frontiers Media S. A.
Frontiers in Immunology, Vol 9 (2019)
IgA binding to FcαRI (CD89) is rapidly enhanced by cytokine induced inside-out signaling. Dephosphorylation of serine 263 in the intracellular tail of FcαRI by PP2A and PI3K activation are instrumental in this process. To further investigate these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ee8419afff7f74b1830ea8ddb8fcb0
https://dspace.library.uu.nl/handle/1874/377319
https://dspace.library.uu.nl/handle/1874/377319
Autor:
Cornelis K. van der Ent, Leo Koenderman, Madelon Bracke, Ellen S. Koster, Anke-Hilse Maitland-van der Zee, Dirkje S. Postma, Gerard H. Koppelman, Jan A. M. Raaijmakers
Publikováno v:
Pharmacogenomics, 10(8), 1351-1361. FUTURE MEDICINE LTD
Aims: To investigate the effects of genetic variation on treatment response to asthma medication in children and to identify (profiles of) SNPs that characterize response phenotypes. Material & methods: The Pharmacogenetics of Asthma medication in Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6786e2bbbb0574078a28b46018fcb5
https://doi.org/10.2217/pgs.09.79
https://doi.org/10.2217/pgs.09.79
Autor:
Liset van Dijk, Madelon Bracke, Hubert G. M. Leufkens, Bert Brunekreef, Peter Spreeuwenberg, Hubertus G. M. Arets, Mira G. P. Zuidgeest, Henriette A. Smit
Publikováno v:
Annals of Family Medicine, 7(1), 32-40. ANNALS FAMILY MEDICINE
PURPOSE Diagnosing asthma in children with asthmatic symptoms remains a challenge, particularly in preschool children. This challenge creates an opportu- nity for variability in prescribing. The aim of our study was to investigate how and to what deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5291627a9a8377266e38130ea91f378
https://doi.org/10.1370/afm.910
https://doi.org/10.1370/afm.910
Autor:
Hubert G. M. Leufkens, Alet H. Wijga, Henriette A. Smit, Mira G. P. Zuidgeest, Johan C. de Jongste, Madelon Bracke, Marjan Kerkhof, Maarten O. Hoekstra, Bert Brunekreef, Jorrit Gerritsen
Publikováno v:
Respiratory Medicine, 102(10), 1446-1451. W B SAUNDERS CO LTD
Respiratory Medicine, 102, 1446-1451. W.B. Saunders
Respiratory Medicine, 102, 1446-1451. W.B. Saunders
Objective: In young children with asthmatic symptoms diagnostic difficulties lead to use of trials of asthma medication as a diagnostic tool. Our aim is to quantify the persistent use of asthma medication, initiated in the first year of life and iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84843e812905d92179e945561222c59e
https://research.rug.nl/en/publications/d2401671-42b1-4598-98d0-0f729521807e
https://research.rug.nl/en/publications/d2401671-42b1-4598-98d0-0f729521807e
Autor:
Tjeerd van Staa, Jan-Willem J. Lammers, Frank de Vries, Hubert G. M. Leufkens, Madelon Bracke, Olaf H. Klungel, S Pouwels
Publikováno v:
British Journal of Clinical Pharmacology, 65(4), 580-6. Wiley
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: * Use of beta(2) agonists has been associated with tachycardia, an abnormal ECG and atrial fibrillation. * Previous observational studies of the association between use of beta(2) agonists and the risk of acu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982cabfa269ff083b05672a4bd6c369f
https://doi.org/10.1111/j.1365-2125.2007.03077.x
https://doi.org/10.1111/j.1365-2125.2007.03077.x
Autor:
Madelon Bracke, S Pouwels, Olaf H. Klungel, Tjeerd van Staa, Jan-Willem J. Lammers, Frank de Vries, Hubert G. M. Leufkens
Publikováno v:
Journal of Hypertension. 26:124-129
BACKGROUND: Use of inhaled corticosteroids may reduce the risk of acute myocardial infarction (MI) through reductions in systemic inflammation and C-reactive protein. OBJECTIVES: To examine the association between the use of inhaled corticosteroids a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498c7f1929e5358a23f3cd7203ba1ecd
https://doi.org/10.1097/hjh.0b013e3282f0ab4a
https://doi.org/10.1097/hjh.0b013e3282f0ab4a
Autor:
Corneli van Aalst, Hubert G. M. Leufkens, Deon Kanters, Bart Luijk, René C. Schweizer, Madelon Bracke, Willem ten Hove, Leo Koenderman, Jan-Willem J. Lammers, Jan A. M. Raaijmakers
Publikováno v:
Journal of Allergy and Clinical Immunology. 120:1073-1081
Background Allergic asthma is associated with chronic airway and systemic immune responses. Systemic responses include priming of peripheral blood eosinophils, which is enhanced after allergen challenge. In a subpopulation of asthmatic subjects, neut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6e01e3a8812bd159135a4c15e9192b
https://doi.org/10.1016/j.jaci.2007.06.021
https://doi.org/10.1016/j.jaci.2007.06.021
Publikováno v:
Molecular Immunology. 44:2492-2496
P38 MAPK is a central mediator in cytokine signalling in human leukocytes. P38 MAPK is activated by phosphorylation of a conserved Thr180-X-Tyr182 motif by dual phosphorylation via the upstream kinases MKK3 and MKK6. Alternatively, P38 MAPK can be ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc8c04fbca40b7248cadb45a019f08f
https://doi.org/10.1016/j.molimm.2006.10.009
https://doi.org/10.1016/j.molimm.2006.10.009
Autor:
Hubert G. M. Leufkens, Madelon Bracke, Eugène van Puijenbroek, Marie L. De Bruin, Arno W. Hoes
Publikováno v:
Pharmacoepidemiology and Drug Safety. 15:99-105
SUMMARY Purpose The bottleneck in pharmacogenetic research on rare adverse drug reactions (ADR) is retrieval of patients. Spontaneous reports of ADRs may form a useful source of patients. We investigated the feasibility of a pharmacogenetic study, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57afa5fcfc4a5a094da0d0549b6eded6
https://doi.org/10.1002/pds.1194
https://doi.org/10.1002/pds.1194