Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Madeline J Stewart"'
Autor:
Linyue Shang, Huimei Wei, Jing Deng, Madeline J. Stewart, Johnathan E. LeSaint, Annet Kyomuhangi, Shawn Park, Elise C. Maul, Chang-Guo Zhan, Fang Zheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract It is recognized as a promising therapeutic strategy for cocaine use disorder to develop an efficient enzyme which can rapidly convert cocaine to physiologically inactive metabolites. We have designed and discovered a series of highly effici
Externí odkaz:
https://doaj.org/article/eeaa4ba4e86944dab6007d0ff59edf53
Autor:
Lauren M. Weaver, Madeline J. Stewart, Kai Ding, Charles D. Loftin, Fang Zheng, Chang-Guo Zhan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Abdominal aortic aneurysm (AAA) is a deadly, permanent ballooning of the aortic artery. Pharmacological and genetic studies have pointed to multiple proteins, including microsomal prostaglandin E2 synthase-1 (mPGES-1), as potentially promisi
Externí odkaz:
https://doaj.org/article/719d64beb3d04e969ef849bcfb2a61e3
Autor:
Madeline J. Stewart, Lauren M. Weaver, Kai Ding, Annet Kyomuhangi, Charles D. Loftin, Fang Zheng, Chang-Guo Zhan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The growing opioid use and overdose crisis in the US is closely related to the abuse of pain medications. Particularly for postoperative pain (POP), ~ 310 million major surgeries are performed globally per year. Most patients undergoing surg
Externí odkaz:
https://doaj.org/article/8c5238deb2454e65a372bea92237677f
Autor:
Lauren M Weaver, Madeline J Stewart, Kai Ding, Shuo Zhou, Charles Loftin, Fang Zheng, Chang-Guo Zhan
Publikováno v:
Circulation. 144
Background: Abdominal aortic aneurysm (AAA) is a deadly, permanent balloon of the aortic artery. Surgery is the only option available to patients, but it is risky. In addition, there are currently no FDA-approved pharmacological treatments for AAA av
Publikováno v:
Chem Biol Interact
Human butyrylcholinesterase (BChE) is a widely distributed plasma enzyme. For decades, numerous research efforts have been directed at engineering BChE as a bioscavenger of organophosphorus insecticides and chemical warfare nerve agents. However, it
Autor:
Stewart, Madeline J.1,2 (AUTHOR), Weaver, Lauren M.1,2 (AUTHOR), Ding, Kai1 (AUTHOR), Kyomuhangi, Annet1,2 (AUTHOR), Loftin, Charles D.2 (AUTHOR), Zheng, Fang1,2 (AUTHOR) fzhen2@uky.edu, Zhan, Chang-Guo1,2 (AUTHOR) zhn@uky.edu
Publikováno v:
Scientific Reports. 2/27/2023, Vol. 13 Issue 1, p1-13. 13p.
Publikováno v:
Drug Week; 6/7/2024, p2960-2960, 1p
Publikováno v:
Pain & Central Nervous System Week; 4/3/2023, p2832-2832, 1p