Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Madeline J Churchill"'
Autor:
Marco A S Baptista, Kuldip D Dave, Mark A Frasier, Todd B Sherer, Melanie Greeley, Melissa J Beck, Julie S Varsho, George A Parker, Cindy Moore, Madeline J Churchill, Charles K Meshul, Brian K Fiske
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80705 (2013)
The objective of this study was to evaluate the pathology time course of the LRRK2 knockout rat model of Parkinson's disease at 1-, 2-, 4-, 8-, 12-, and 16-months of age. The evaluation consisted of histopathology and ultrastructure examination of se
Externí odkaz:
https://doaj.org/article/91c01268d8074bafbcbd4a7729d3872b
Autor:
Madeline J. Churchill, Haley du Bois, Taylor A. Heim, Tenny Mudianto, Maria M. Steele, Jeffrey C. Nolz, Amanda W. Lund
Publikováno v:
Journal of Experimental Medicine. 219
Lymphatic vessels are often considered passive conduits that flush antigenic material, pathogens, and cells to draining lymph nodes. Recent evidence, however, suggests that lymphatic vessels actively regulate diverse processes from antigen transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95e0609f7a4ad0cc5e3ccd447be56e0
https://doi.org/10.1084/jem.20211830
https://doi.org/10.1084/jem.20211830
Autor:
Pauline Janssen, Laurence Ris, Ann Massie, Charles K. Meshul, Olaya Lara, Lutgarde Arckens, Emmanuel Hermans, Robert E. McCullumsmith, Lise Verbruggen, Madeline J Churchill, Hideyo Sato, Noemi Declerck, Adam J. Funk, Cynthia Moore, Sinead M. O’Donovan, Eduard Bentea, Laura De Pauw, Agnès Villers, Erica A K DePasquale
Publikováno v:
Molecular Psychiatry, Vol. 26, no. 9, p. 4754-4769 (2021)
Molecular psychiatry
Molecular psychiatry
The astrocytic cystine/glutamate antiporter system xc− represents an important source of extracellular glutamate in the central nervous system, with potential impact on excitatory neurotransmission. Yet, its function and importance in brain physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f948bd085779f30a8470e3075ba486
https://doi.org/10.1038/s41380-020-0751-3
https://doi.org/10.1038/s41380-020-0751-3
Autor:
Cynthia Moore, Michelle S. Massaquoi, William A. Liguore, Madeline J Churchill, Charles K. Meshul, Heather L. Melrose
Publikováno v:
Neuroscience. 433:53-71
Parkinson’s disease (PD) is caused by neurodegeneration of nigrostriatal neurons, resulting in dopamine (DA) stimulated motor deficits. Like brain derived neurotrophic factor (BDNF), 7,8-dihydroxyflavone (DHF) is an agonist of the tropomyosin recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc8b483808db6485f0ff3b5cd5902c6
https://doi.org/10.1016/j.neuroscience.2020.02.046
https://doi.org/10.1016/j.neuroscience.2020.02.046
Autor:
H. du Bois, M. M. Steele, T. A. Heim, J. C. Nolz, T. Mudianto, Madeline J Churchill, Amanda W. Lund
Lymphatic vessels are often considered passive conduits that rapidly flush antigenic material, pathogens, and cells to draining lymph nodes. Recent evidence, however, suggests that lymphatic vessels actively regulate diverse processes from antigen tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7649a379e77e0feb42017facd92ff8f8
https://doi.org/10.1101/2021.08.26.457551
https://doi.org/10.1101/2021.08.26.457551
Autor:
Karthik Mouli, Elena Kamynina, Seth A. Peng, Becca A. Flitter, Bridget M. Mooney, Pamela Campioli, Rebecca L. Cubitt, Michael J. Shanahan, Isabella Rauch, Simon P. Früh, Oyebola O. Oyesola, James D. Lord, Marija S. Nadjsombati, Praveen Sethupathy, Madeline J Churchill, Jakob von Moltke, Shuchi Smita, Karsten Gronert, Macy K. Matheson, Duc H. Pham, Matt Kanke, Jordan L. Cahoon, Elia D. Tait Wojno, Pavithra Sundaravaradan, John W. McGinty, Lauren M. Webb
Publikováno v:
The Journal of Experimental Medicine
Type 2 cytokines promote epithelial changes that help to expel worms during intestinal helminth infection. Oyesola et al. show that prostaglandin D2 and its receptor CRTH2 are novel negative regulators of this response, dampening the Type 2 cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634e6869920806c0d6f27c6239769b1e
http://europepmc.org/articles/PMC8294949
http://europepmc.org/articles/PMC8294949
Autor:
Cynthia Moore, Ella A. Kasanga, Mark A. Cantu, Michael F. Salvatore, Madeline J Churchill, Charles K. Meshul
Publikováno v:
Neuroscience. 414:8-27
Parkinson's disease (PD) is the second most common neurodegenerative disease and there are no effective treatments that either slow or reverse the degeneration of the dopamine (DA) pathway. Using a 4-week progressive MPTP (1-methyl-1,2,3,6-tetrahydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cc744aa3f051d6b8afc2f62797fe0d
https://doi.org/10.1016/j.neuroscience.2019.06.006
https://doi.org/10.1016/j.neuroscience.2019.06.006
Autor:
Madeline J Churchill, Isabella Rauch
Publikováno v:
The Journal of Immunology. 208:115.05-115.05
The small intestinal epithelium is exposed to various microbes, and intestinal epithelial cells (IECs) have developed an array of host defense mechanisms to distinguish commensals from pathogenic microbes and initiate an immune response against the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f17ffe4841375da84af1d6d3da8eec
https://doi.org/10.4049/jimmunol.208.supp.115.05
https://doi.org/10.4049/jimmunol.208.supp.115.05
Autor:
L. Pflibsen, Cynthia Moore, Michelle D Sconce, K. Kim, Madeline J Churchill, Charles K. Meshul
Publikováno v:
Neuroscience. 359:224-247
Many clinical studies have reported on the benefits of exercise therapy in patients with Parkinson's disease (PD). Exercise cannot stop the progression of PD or facilitate the recovery of dopamine (DA) neurons in the substantia nigra pars compacta (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80db759ea9106642c39c67b258716216
https://doi.org/10.1016/j.neuroscience.2017.07.031
https://doi.org/10.1016/j.neuroscience.2017.07.031
Autor:
Charles K. Meshul, Lise Verbruggen, Eduard Bentea, Madeline J Churchill, Lauren Deneyer, Rebecca L. Hood, Ann Massie, Cynthia Moore
Publikováno v:
Brain Research Bulletin. 130:257-267
In Parkinson's disease, striatal dopamine depletion leads to plastic changes at excitatory corticostriatal and thalamostriatal synapses. The functional consequences of these responses on the expression of behavioral deficits are incompletely understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26bcb25b19280a2e924c3895ef00525
https://doi.org/10.1016/j.brainresbull.2017.02.005
https://doi.org/10.1016/j.brainresbull.2017.02.005