Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Madeline Dans"'
Autor:
Rebecca C. S. Edgar, Tess R. Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A. Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D. Suraweera, Ric N. Price, Sergio Wittlin, Vicky M. Avery, Nyssa Drinkwater, Susan A. Charman, Darren J. Creek, Tania F. de Koning-Ward, Peter J. Scammells, Sheena McGowan
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT To combat the global burden of malaria, development of new drugs to replace or complement current therapies is urgently required. Here, we show that the compound MMV1557817 is a selective, nanomolar inhibitor of both Plasmodium falciparum an
Externí odkaz:
https://doaj.org/article/2d940180a1bd41efa98e153bebf7c041
Autor:
Sophie Collier, Emma Pietsch, Madeline Dans, Dawson Ling, Tatyana A. Tavella, Sash Lopaticki, Danushka S. Marapana, Mohini A. Shibu, Dean Andrew, Snigdha Tiash, Paul J. McMillan, Paul Gilson, Leann Tilley, Matthew W. A. Dixon
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The malaria parasite uses actin-based mechanisms throughout its lifecycle to control a range of biological processes including intracellular trafficking, gene regulation, parasite motility and invasion. In this work we assign functions to th
Externí odkaz:
https://doaj.org/article/d3c8a12f20e44c7d8d555c7fba430808
Autor:
Sreejoyee Ghosh, Scott A Chisholm, Madeline Dans, Asha Lakkavaram, Kit Kennedy, Stuart A Ralph, Natalie A Counihan, Tania F de Koning-Ward
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193538 (2018)
The ability of Plasmodium parasites to egress from their host red blood cell is critical for the amplification of these parasites in the blood. Previous forward chemical genetic approaches have implicated the subtilisin-like protease (SUB1) and the c
Externí odkaz:
https://doaj.org/article/fe4e9dc4fac34c4ea30a511940745b33