Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Madelen M. Díaz"'
Publikováno v:
Cell Death & Differentiation. 30:397-406
Hallmark pathological features of brain trauma are axonal degeneration and demyelination because myelin-producing oligodendrocytes (OLs) are particularly vulnerable to injury-induced death signals. To reveal mechanisms responsible for this OL loss, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8612d146269c990b64e5c4e49c775004
https://doi.org/10.1038/s41418-022-01091-z
https://doi.org/10.1038/s41418-022-01091-z
Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity
Publikováno v:
eLife, Vol 8 (2019)
Animal circadian rhythms persist in constant darkness and are driven by intracellular transcription-translation feedback loops. Although these cellular oscillators communicate, isolated mammalian cellular clocks continue to tick away in darkness with
Externí odkaz:
https://doaj.org/article/a7ff6fa3445b4ed1b1d536be98cf21f4
Autor:
Stephen A. Tapanes, Dena Arizanovska, Madelen M. Díaz, Oluwarotimi O. Folorunso, Theresa Harvey, Stephanie E. Brown, Inna Radzishevsky, Liesl N. Close, Jonathan R. Jagid, Joacir Graciolli Cordeiro, Herman Wolosker, Darrick T. Balu, Daniel J. Liebl
Publikováno v:
Glia. 70:1133-1152
Synaptic damage is one of the most prevalent pathophysiological responses to traumatic CNS injury and underlies much of the associated cognitive dysfunction; however, it is poorly understood. The D-amino acid, D-serine, serves as the primary co-agoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18fbf3679c0df285f31eacd69680012
https://doi.org/10.1002/glia.24161
https://doi.org/10.1002/glia.24161
Autor:
Coleen M. Atkins, Madelen M Díaz, Yanina Tsenkina, Stephen A. Tapanes, Ross Bullock, Daniel J. Liebl, David J. Titus, Shyam Gajavelli
Publikováno v:
Brain Communications
Clinical trials examining neuroprotective strategies after brain injury, including those targeting cell death mechanisms, have been underwhelming. This may be in part due to an incomplete understanding of the signalling mechanisms that induce cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f94556d583164d3f157ad0ef730fff2
https://doi.org/10.1093/braincomms/fcaa175
https://doi.org/10.1093/braincomms/fcaa175
Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Animal circadian rhythms persist in constant darkness and are driven by intracellular transcription-translation feedback loops. Although these cellular oscillators communicate, isolated mammalian cellular clocks continue to tick away in darkness with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9794d0217265076ae086d77ea17e5ec7
Six neuropeptides are expressed within the Drosophila brain circadian network. Our previous mRNA profiling suggested that AllatostatinC is a seventh neuropeptide and specifically expressed in dorsal clock neurons (DN1s). Our results here show that As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fb73ed013fc00ff71859c48d0c017a
https://doi.org/10.1101/361048
https://doi.org/10.1101/361048
Autor:
Patrick Weidner, Pamela Menegazzi, Madelen M. Díaz, Michael Rosbash, Elena Dalla Benetta, Matthias Schlichting, Charlotte Helfrich-Förster
Publikováno v:
Current Biology. 29:3266-3276.e3
Summary The circadian clock is a timekeeper but also helps adapt physiology to the outside world. This is because an essential feature of clocks is their ability to adjust (entrain) to the environment, with light being the most important signal. Wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed67bccf2ce7c568f4b977c071c06f29
https://doi.org/10.1016/j.cub.2019.08.033
https://doi.org/10.1016/j.cub.2019.08.033
Publikováno v:
Current Biology. 29:13-22.e3
Summary Seven neuropeptides are expressed within the Drosophila brain circadian network. Our previous mRNA profiling suggested that Allatostatin-C (AstC) is an eighth neuropeptide and specifically expressed in dorsal clock neurons (DN1s). Our results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68d72e427012a25d8ddd139241039a9
https://doi.org/10.1016/j.cub.2018.11.005
https://doi.org/10.1016/j.cub.2018.11.005
Publikováno v:
Neuron. 100:624-635.e4
The Drosophila core circadian circuit contains distinct groups of interacting neurons that give rise to diurnal sleep-wake patterns. Previous work showed that a subset of dorsal neurons 1 (DN1s) are sleep-promoting through their inhibition of activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef3c31ada16cc410c4452d0b1cfa90d
https://doi.org/10.1016/j.neuron.2018.09.002
https://doi.org/10.1016/j.neuron.2018.09.002
Autor:
Aoife McMahon, Hua Jin, Madelen M. Díaz, Michael Rosbash, Eranthie Weerapana, Allegra Fieldsend, Shalise M. Couvertier, Fang Guo, Weifei Luo
Publikováno v:
Neuron. 99:768-780.e3
Drosophila NonA and its mammalian ortholog NONO are members of the Drosophila behavior and human splicing (DBHS) family. NONO also has a strong circadian connection: it associates with the circadian repressor protein PERIOD (PER) and contributes to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6223c9d5105313d5ba60d21726973019
https://doi.org/10.1016/j.neuron.2018.07.001
https://doi.org/10.1016/j.neuron.2018.07.001