Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Madeleine Strickland"'
Publikováno v:
Viruses, Vol 13, Iss 6, p 1147 (2021)
Two decades ago, Tsg101, a component of the Endosomal Sorting Complexes Required for Transport (ESCRT) complex 1, was identified as a cellular factor recruited by the human immunodeficiency virus type 1 (HIV-1) to facilitate budding of viral particle
Externí odkaz:
https://doaj.org/article/5c181bb7926643de842a6fda8687ad90
Autor:
Madeleine Strickland, Lorna S. Ehrlich, Susan Watanabe, Mahfuz Khan, Marie-Paule Strub, Chi-Hao Luan, Michael D. Powell, Jonathan Leis, Nico Tjandra, Carol A. Carter
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Tsg101 is a component of the host cellular ESCRT machinery and is required for HIV-1 replication. Here, the authors show that disruption of ubiquitin binding of the Tsg101 UEV domain through commonly used drugs arrests virus assembly, which might fac
Externí odkaz:
https://doaj.org/article/2ecc918c7b1b4a77b36ae1b966756894
Publikováno v:
Viruses, Vol 12, Iss 4, p 447 (2020)
The ESCRT-I factor Tsg101 is essential for sorting endocytic cargo and is exploited by viral pathogens to facilitate egress from cells. Both the nucleocapsid (NC) domain and p6 domain in HIV-1 Gag contribute to recruitment of the protein. However, th
Externí odkaz:
https://doaj.org/article/e07e2a9aa43c4f4382c93deb62d81496
Autor:
Madeleine Strickland, Nico Tjandra, Rolf E. Swenson, Ana Christina L. Opina, Olga Vasalatiy, Yong Sok Lee
Publikováno v:
Inorg Chem
Polymethylated lanthanide 4S4R-M4DOTMA complexes bearing the ring methyl groups oriented in the SSSS position and the arm methyl groups in the RRRR configuration, exists exclusively as the SAP [Λ(δδδδ)] isomer in solution throughout the lanthani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a456eee977e314fbd2a39364f44b3240
https://doi.org/10.1021/acs.inorgchem.9b02049
https://doi.org/10.1021/acs.inorgchem.9b02049
Publikováno v:
Biophys J
Proteins interact with one another across a broad spectrum of affinities. Our understanding of the low end of this spectrum, as characterized by millimolar dissociation constants, relies on a handful of cases in which weak encounters have experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc407628d2262a101ba95a59371001c
https://doi.org/10.1016/j.bpj.2019.09.035
https://doi.org/10.1016/j.bpj.2019.09.035
Autor:
Nico Tjandra, Rohith Rajasekaran, Jan Marchant, Guillermo A. Bermejo, Madeleine Strickland, Colin T. O’Hern, Michael F. Summers, Jonathan Catazaro, Marie-Paule Strub
Publikováno v:
Journal of the American Chemical Society. 141:1430-1434
NMR has provided a wealth of structural and dynamical information for RNA molecules of up to ∼50 nucleotides, but its application to larger RNAs has been hampered in part by difficulties establishing global structural features. A potential solution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f39273a5454a578974fb4210a14dd1
https://doi.org/10.1021/jacs.8b11384
https://doi.org/10.1021/jacs.8b11384
Publikováno v:
Viruses, Vol 13, Iss 1147, p 1147 (2021)
Viruses
Viruses
Two decades ago, Tsg101, a component of the Endosomal Sorting Complexes Required for Transport (ESCRT) complex 1, was identified as a cellular factor recruited by the human immunodeficiency virus type 1 (HIV-1) to facilitate budding of viral particle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1458601147b63b6d1095c99013c3ac
https://pubmed.ncbi.nlm.nih.gov/34203832
https://pubmed.ncbi.nlm.nih.gov/34203832
Autor:
E. Keith Keenan, Kishore K. Mahalingan, Martin E. Tanner, Antonina Roll-Mecak, Madeleine Strickland, Haydn L. Ball, Yanjie Liu, Nico Tjandra, Yan Li
Glutamylation, introduced by TTLL enzymes, is the most abundant modification of brain tubulin. Essential effector proteins read the tubulin glutamylation pattern, and its misregulation causes neurodegeneration. TTLL glutamylases posttranslationally a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7bfccd10b04b0c988bb289eaabb273
https://doi.org/10.1101/2020.06.07.139295
https://doi.org/10.1101/2020.06.07.139295
Autor:
Veronica Soloveva, Arthur J. Goff, Xiaofan Li, Lorna S. Ehrlich, Nico Tjandra, Charles B. Stauft, Madeleine Strickland, Carol A. Carter, Sumita Bhaduri-McIntosh, Susan M. Watanabe
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Two proton pump inhibitors, tenatoprazole and esomeprazole, were previously shown to inhibit HIV-1 egress by blocking the interaction between Tsg101, a member of the ESCRT-I complex, and ubiquitin. Here, we deepen our understanding of prazole budding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd41ee608ca5bf199afca18345df204
http://europepmc.org/articles/PMC7055211
http://europepmc.org/articles/PMC7055211
Autor:
Steven M. Bonn, Susan Watanabe, Madeleine Strickland, Christina M. Camara, Carol A. Carter, Nico Tjandra, David Fushman
Publikováno v:
SSRN Electronic Journal.
The ESCRT-I protein Tsg101 plays a critical role in viral budding and endocytic sorting. Although Tsg101 is known to recognize monoubiquitin (Ub1), here we show for the first time that it can also bind several diubiquitins (Ub2), with a preference fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c316726ee9c3d865c5dd5bdd0a7447
https://doi.org/10.2139/ssrn.3537944
https://doi.org/10.2139/ssrn.3537944