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of 6
pro vyhledávání: '"Madeleine S. A. Tan"'
Autor:
Madeleine S. A. Tan, Preeti Pandey, James R. Falconer, Dan J. Siskind, Alexandra Balmanno, Harendra S. Parekh
Publikováno v:
Gels, Vol 8, Iss 1, p 38 (2022)
(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers a promising approach. This study aims to develop clozapine-encapsulated thermosensitive so
Externí odkaz:
https://doaj.org/article/58cae52c10f84ce894b2a34a3b801b1a
Autor:
Madeleine S. A. Tan, Preeti Pandey, Rink-Jan Lohman, James R. Falconer, Dan J. Siskind, Harendra S. Parekh
Publikováno v:
Molecular pharmaceutics. 19(11)
Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia. However, it causes many adverse drug reactions (ADRs), which lead to poor treatment outcomes. Nose-to-brain (N2B) drug delivery offers a promising approach to reduce
Autor:
Madeleine S. A. Tan, Preeti Pandey, James R. Falconer, Dan J. Siskind, Alexandra Balmanno, Harendra S. Parekh
Publikováno v:
Gels
Gels, Vol 8, Iss 38, p 38 (2022)
Gels; Volume 8; Issue 1; Pages: 38
Gels, Vol 8, Iss 38, p 38 (2022)
Gels; Volume 8; Issue 1; Pages: 38
(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers a promising approach. This study aims to develop clozapine-encapsulated thermosensitive so
Autor:
Peter M. Moyle, James R. Falconer, Madeleine S. A. Tan, Kristofer J. Thurecht, Faheem Maqbool
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology. 46:1186-1192
Supercritical fluid (SCF) technology offers a potential green alternative to organic solvent-based methods for drug formulation. Albendazole (ABZ) has promising anticancer activity when formulated to increase its cellular uptake. Herein, a static vol
Autor:
James R. Falconer, Dan Siskind, Faraz Honarparvar, Harendra S. Parekh, Preeti Pandey, Madeleine S. A. Tan
Publikováno v:
Psychopharmacology. 238(3)
Clozapine is the most effective antipsychotic for treatment-refractory schizophrenia for reducing positive psychotic symptoms. It is associated with a reduction in hospitalisation and overall mortality. In spite of this, clozapine remains underutilis
Publikováno v:
Expert opinion on drug delivery. 17(6)
Orally-administered antipsychotics are effective in the management of psychosis-related disorders although generation-specific adverse drug reactions (ADRs) significantly hinder clinical outcomes, driven by issues such as patient non-compliance. Dire