Výsledky vyhledávání - "Madeleine Pralavorio"

The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes

Autor: Roger Rahmani, Pierre Lesca, Madeleine Pralavorio, Géraldine Lemaire, N. Ledirac, C. Delescluse

Publikováno v: Life Sciences
Life Sciences, Elsevier, 2004, 74, pp.2265-2278

Benzimidazoles compounds like omeprazole (OME) and thiabendazole (TBZ) mediate CYP1A1 induction differently from classical aryl hydrocarbon receptor (AhR) ligands, 3-methylcholanthrene (3-MC) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). To clarify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb2fff108ec0d3683fa4a314a16d812
https://doi.org/10.1016/j.lfs.2003.09.056

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Diflubenzuron, a Benzoyl-Urea Insecticide, Is a Potent Inhibitor of TCDD-Induced CYP1A1 Expression in HepG2 Cells

Autor: Pierre Lesca, G. de Sousa, Madeleine Pralavorio, C. Delescluse, Ronald N. Hines, Marie P. Piechocki, Roger Rahmani, N. Ledirac

Publikováno v: Toxicology and Applied Pharmacology. 164:273-279

Diflubenzuron (DFB) belongs to a group of compounds called benzoyphenyl ureas acting as chitin synthesis inhibitors, which also inhibit growth of B16 murine melanomas. The present study was designed to investigate the effect of this insecticide, on C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fd4484abeae25126aadd50e40bdc0f
https://doi.org/10.1006/taap.2000.8920

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Drosophila melanogaster acetylcholinesterase: Identification and expression of two mutations responsible for cold- and heat-sensitive phenotypes

Autor: Didier Fournier, Madeleine Pralavorio, Jean-Marc Bride, Annick Mutero

Publikováno v: Molecular and General Genetics MGG. 243:699-705

AceIJ29 and AceIJ40 are cold- and heat-sensitive variants of the gene coding for acetylcholinesterase in Drosophila melanogaster. In the homozygous condition, these mutations are lethal when animals are raised at restrictive temperatures, i.e., below

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be13490e62cb54d5112925ef2233abd
https://doi.org/10.1007/bf00279580

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Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase

Autor: Annick Mutero, Jean-Marc Bride, Madeleine Pralavorio, Didier Fournier

Publikováno v: Proceedings of the National Academy of Sciences. 91:5922-5926

Extensive utilization of pesticides against insects provides us with a good model for studying the adaptation of a eukaryotic genome to a strong selective pressure. One mechanism of resistance is the alteration of acetylcholinesterase (EC 3.1.1.7), t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a508ccc41de1ffd5a70227cedd39c9e
https://doi.org/10.1073/pnas.91.13.5922

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Drosophila acetylcholinesterase: Mechanisms of resistance to organophosphates

Autor: Didier Fournier, Annick Mutero, Madeleine Pralavorio, Jean-Marc Bride

Publikováno v: Chemico-Biological Interactions. 87:233-238

Quantitative and qualitative changes of acetylcholinesterase can affect the sensitivity of insects to insecticides. First, the amount of acetylcholinesterase in the central nervous system is important in Drosophila melanogaster, flies which overexpre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f18d8451d64688333b16c65e54b9222
https://doi.org/10.1016/0009-2797(93)90047-3

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Comparative study of CYP1A1 induction by 3-methylcholanthrene in various human hepatic and epidermal cell types

Autor: C. Delescluse, Roger Rahmani, D. Botta-Fridlund, Madeleine Pralavorio, G. de Sousa, Y. Letreut, N. Ledirac

Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 1997, pp.443-450

Hepatocytes and keratinocytes are among the most widely used cells in pharmaco-toxicology, but a limitation of these models is the provision of human tissues on a regular basis. The suitability of HepG2, HaCaT and HESV cell lines as an acceptable sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a99578965236b7ca4eab064a0747cd1
https://pubmed.ncbi.nlm.nih.gov/20654333

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Characterization of microsomal oxidative activities in a wild-type and in a DDT resistant strain of Drosophila melanogaster

Autor: Madeleine Pralavorio, Jean Baptiste Berge, Didier Fournier, David Pauron, Daniel Weissbart, René Lafont, Reinhard Lange, Christian Larroque, Jean Pierre Salaun, André Cuany, Catherine Blais

Publikováno v: Pesticide Biochemistry and Physiology
Pesticide Biochemistry and Physiology, Elsevier, 1990, 37 (3), pp.293-302

Resistance of a laboratory selected DDT strain of Drosophila melanogaster (RalDDT R ) has been found to be monofactorial and correlated to an increased level of activity of the cytochrome P450-dependent mixed function oxidase (MFO). Both strains meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f71f2b66abda597c04fdc70802fd83
https://doi.org/10.1016/0048-3575(90)90136-p

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Cytotoxic effects and induction of cytochromes P450 1A1/2 by insecticides, in hepatic or epidermal cells: binding capability to the Ah receptor

Autor: Roger Rahmani, Pierre Lesca, Madeleine Pralavorio, C. Delescluse, G. de Sousa, N. Ledirac

Publikováno v: Toxicology Letters
Toxicology Letters, Elsevier, 1998, 96 (7), pp.33-39

Insecticides deserve particular attention since the general population is potentially exposed to such chemicals through many routes. We therefore tested the comparative acute and chronic toxicity of chemicals belonging to the major insecticides famil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf84c795714834428bb3067368400c5e
https://pubmed.ncbi.nlm.nih.gov/9820645

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Carbaryl induces CYP1A1 gene expression in HepG2 and HaCaT cells but is not a ligand of the human hepatic Ah receptor

Autor: Pierre Lesca, G. de Sousa, C. Delescluse, Marcel Amichot, Madeleine Pralavorio, Roger Rahmani, Jean-Baptiste Bergé, N. Ledirac

Publikováno v: Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, Elsevier, 1997, 144 (1), pp.177-182

In spite of increasing numbers of insecticides used in agriculture, there are serious concerns regarding the potential risks of exposure to these agents. Carbaryl is one of the most important carbamate insecticides and has been used for about 30 year

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b047f0eed0d3b1bb6f07907258bfceae
https://pubmed.ncbi.nlm.nih.gov/9169082

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Insecticide cytotoxicity and CYP1A1/2 induction in primary human and rat hepatocyte cultures

Autor: Roger Rahmani, Madeleine Pralavorio, D. Botta-Fridlund, Frank Fontaine, Y. Letreut, G. de Sousa

Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 1997, pp.451-457

With the increasing demand for insecticide products, the question of their safety has become one of the serious world public health concerns. The capability of compounds belonging to the major insecticide families [such as chlorinated hydrocarbons (D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc196b02b2ea01a88548e2d8b4b217d2
https://hal.inrae.fr/hal-02686118

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