Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Madeleine Livendahl"'
Autor:
Madeleine Livendahl, Cyril Gerbeaux, Marion Rusch, Maude Patoor, Laure C. Bouchez, Neil John Press
Publikováno v:
Synlett. 28:1219-1223
β-(2-Pyridyl) ketones are a unique class of heterocycles with valuable physicochemical properties and emerging relevance as pharmacophores. Herein we report a one-step process for the preparation of various substituted β-(2-pyridyl) ketones from th
Autor:
Erik Chorell, T. Görlich, Nasim Sabouri, Madeleine Livendahl, Mattias Hedenström, Jan Jamroskovic
Publikováno v:
Organic & Biomolecular Chemistry. 15:3265-3275
G-quadruplex (G4) DNA structures are involved in many important biological processes and can be linked to several human diseases. Drug-like low molecular weight compounds that target G4 structures are therefore interesting not only for their potentia
Publikováno v:
Chemistry - A European Journal. 22:18932-18943
Small molecules are used in the G-quadruplex (G4) research field in vivo and in vitro, and there are increasing demands for ligands that selectively stabilize different G4 structures. Thioflavin T (ThT) emits an enhanced fluorescence signal when bind
Autor:
Esther K. Schmitt, Christian Studer, Patrick Rollin, Madeleine Livendahl, Beatrice Ranieri, Marion Rusch, Carsten Spanka, Arnaud Thevenon, Thomas Aust, Maude Patoor, Laure C. Bouchez, Karl Gademann, Dominic Hoepfner
Publikováno v:
ChemBioChem.
Selective and specific inhibitors of Plasmodium falciparum lysyl-tRNA synthetase represent promising therapeutic antimalarial avenues. Cladosporin was identified as a potent P. falciparum lysyl-tRNA synthetase inhibitor, with an activity against para
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte chemie international edition, 2014, Vol.53(19), pp.4896-4899 [Peer Reviewed Journal]
Angewandte chemie international edition, 2014, Vol.53(19), pp.4896-4899 [Peer Reviewed Journal]
Three natural aromadendrane sesquiterpenes, (−)‐epiglobulol, (−)‐4β,7α‐aromadendranediol, and (−)‐4α,7α‐aromadendranediol, have been synthesized in only seven steps in 12, 15, and 17 % overall yields, respectively, from (E,E)‐fa
Autor:
Lewis C. Cantley, Albert S. Yu, Kannan Karukarichi, Fredrik Karlsson, Ellen Santangelo, Rui Wang, F. Rahm, Ulrika Ericsson, Johan Linstrom, Mariell Pettersson, Jessica Martinsson, Tiago Braga, Madeleine Livendahl, Aine Brigette Henley, Horst Wähling, Lars Boukharta Persson, Martin Andersson, Tobias Ginman, Andreas Hoglund, Parisa Zolfaghari, Rickard Forsblom, Jenny Viklund, Lionel Trésaugues, David L. McElligott, Hyeseok Shim, Antoine Talagas, Tommy Johansson, Kesicki Edward A
Publikováno v:
Blood. 132:213-213
Phosphoinositide signaling is central to many cellular processes including the cell survival pathway known as autophagy. While there is evidence that autophagy can suppress tumorigenesis under certain circumstances, there is increasingly abundant evi
Autor:
Jan Jamroskovic, Erik Chorell, Madeleine Livendahl, Nasim Sabouri, Svetlana Ivanova, Peter Demirel
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(37)
G-quadruplex (G4) structures carry vital biological functions, and compounds that selectively target certain G4 structures have both therapeutic potential and value as research tools. Along this line, 2,2'-diindolylmethanes have been designed and syn
Publikováno v:
Israel Journal of Chemistry. 50:630-651
After being restricted for the intramolecular formation of C–C bonds, the palladium catalyzed arylation reaction has been extended for the intermolecular synthesis of biaryls systems. Many of these reactions have been demonstrated to proceed by mec
Publikováno v:
Tetrahedron Letters. 50:6321-6324
Amino acid-derived thioamides are prepared and evaluated as ligands in the rhodium-catalyzed asymmetric transfer hydrogenation of ketones in 2-propanol. It is found that increasing the steric bulk at the C-terminus of the ligand had a positive impact
Publikováno v:
Platinum Metals Review. 55:212-214