Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Madeleine Laws"'
Autor:
Rom Leidner, Tarsem Moudgil, Carlo Bifulco, Bernard Fox, Christopher Paustian, Hong-Ming Hu, Traci Hilton, Rachel Sanborn, Bryan Bell, Shawn Jensen, Adi Mehta, Fridtjof Lund-Johansen, Madeleine Laws, Glenna McDonnell, Carmen Ballesteros Merino, Marcus Couey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/98aff65146b14f44858301c8e9975a62
Autor:
Madeleine Laws, Pamela B. Cassidy, John W. Bassett, Robert M. Strongin, Tendai Mafireyi, Jorge O. Escobedo
Publikováno v:
Angewandte Chemie. 132:15259-15263
We report the first diselenide-based probe for the selective detection of thioredoxin reductase (TrxR), an enzyme commonly overexpressed in melanomas. The probe design involves conjugation of a seminaphthorhodafluor dye with a diselenide moiety. TrxR
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Madeleine Laws, Sharmeen Chagani, Pamela B. Cassidy, Evan L. Carpenter, Dylan Nelson
Publikováno v:
Molecular Carcinogenesis. 58:1680-1690
Treatment with vemurafenib, a potent and selective inhibitor of mitogen-activated protein kinase signaling downstream of the BRAFV600E oncogene, elicits dramatic clinical responses in patients with metastatic melanoma. Unfortunately, the clinical uti
Autor:
Chelsey D. Kline, Arup K. Indra, Madeleine Laws, Evan L. Carpenter, Sancy A. Leachman, Pamela B. Cassidy, Philip J. Moos
Publikováno v:
Free Radical Biology and Medicine. 128:S64
Our labs have shown that levels of the antioxidant enzyme thioredoxin reductase 1 (TR1) is increased in human malignant melanomas relative to benign nevi (moles), and that TR1 knockdown affects mitochondrial metabolism in human melanomas. Here we rep
Publikováno v:
Journal of Investigative Dermatology. 137:S143