Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Madeleine Gomez"'
Autor:
Blessy George, Xia Wen, Nickie Mercke, Madeleine Gomez, Cindy O’Bryant, Daniel W. Bowles, Yichun Hu, Susan L. Hogan, Melanie S. Joy, Lauren M. Aleksunes
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 571-576 (2020)
Proteins secreted into urine following tubular injury are being increasingly used as biomarkers of clinical and subclinical nephrotoxicity. In the present study, we sought to characterize the time-dependent urinary excretion of three promising biomar
Externí odkaz:
https://doaj.org/article/271201962f0e4c8eb0f71bfffcb20e5a
Autor:
Lauren M. Aleksunes, Nickie Mercke, Brian Buckley, Cindy L. O'Bryant, Yichun Hu, Madeleine Gomez, Susan L. Hogan, Daniel W. Bowles, Melanie S. Joy, Mustafa E Ibrahim, Blessy George, Cara Chang, Xia Wen
Publikováno v:
European Journal of Clinical Pharmacology. 75:51-57
PURPOSE: The ability to predict and detect clinical and subclinical nephrotoxicity early in the course of therapy has the potential to improve long-term outcomes in cancer patients receiving cisplatin chemotherapy. Pharmacokinetic parameters could se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1129fa944a9ee9188ed0254b02003de2
https://doi.org/10.1007/s00228-018-2552-z
https://doi.org/10.1007/s00228-018-2552-z
Autor:
Susan L. Hogan, Cindy L. O'Bryant, Yichun Hu, Blessy George, Madeleine Gomez, Xia Wen, Daniel W. Bowles, Melanie S. Joy, Lauren M. Aleksunes, Nickie Mercke
Publikováno v:
Clinical Pharmacology & Therapeutics. 101:510-518
The success of cisplatin-containing regimens to treat solid tumors is limited, in part, by nephrotoxicity. In rodents, several urinary proteins have emerged that are sensitive indicators of cisplatin-induced kidney injury. We sought to characterize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbb5be993bb2779ba9757bd51649dc3
https://doi.org/10.1002/cpt.606
https://doi.org/10.1002/cpt.606
Autor:
Blessy George, Nickie Mercke, Lauren M. Aleksunes, Cindy L. O'Bryant, Yichun Hu, Daniel W. Bowles, Melanie S. Joy, Xia Wen, Madeleine Gomez, Susan L. Hogan
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 571-576 (2020)
Toxicology Reports, Vol 7, Iss, Pp 571-576 (2020)
Graphical abstract
Highlights • KIM-1, calbindin, and TFF3 are increased in urine of patients prescribed cisplatin. • KIM-1 concentrations remain elevated with subsequent cisplatin treatment cycles. • Calbindin concentrations increased onl
Highlights • KIM-1, calbindin, and TFF3 are increased in urine of patients prescribed cisplatin. • KIM-1 concentrations remain elevated with subsequent cisplatin treatment cycles. • Calbindin concentrations increased onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d075496c5a7681dc98334cefb46cc0
https://pubmed.ncbi.nlm.nih.gov/32382514
https://pubmed.ncbi.nlm.nih.gov/32382514
Autor:
Nickie Mercke, Madeleine Gomez, Cindy L. O'Bryant, Blessy George, Yichun Hu, Xia Wen, Lauren M. Aleksunes, Daniel W. Bowles, Cara Chang, Melanie S. Joy, Susan L. Hogan
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1333 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 7; Pages: 1333
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 7; Pages: 1333
Nephrotoxicity is a dose limiting side effect associated with the use of cisplatin in the treatment of solid tumors. The degree of nephrotoxicity is dictated by the selective accumulation of cisplatin in renal tubule cells due to: (1) uptake by organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2fa83ecd960381603f49189aa06562
http://www.mdpi.com/1422-0067/18/7/1333
http://www.mdpi.com/1422-0067/18/7/1333
Publikováno v:
Medical Psychiatry: Theory and Practice: (In 2 Volumes)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1324177e6ec51c6017463c6c0f8ea96b
https://doi.org/10.1142/9789814541497_0013
https://doi.org/10.1142/9789814541497_0013
