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pro vyhledávání: '"Madeleine Eakman"'
Autor:
Robert A. Langan, Madeleine Eakman, Robin L. Kirkpatrick, Marc J. Lajoie, Jesse G. Zalatan, David Baker, Kieran Lewis, Scott E. Boyken
Publikováno v:
ACS Synth Biol
To spatially control biochemical functions at specific sites within a genome, we have engineered a synthetic switch that activates when bound to its DNA target site. The system uses two CRISPR-Cas complexes to colocalize components of a de novo desig