Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Madeleine Di Natale"'
Autor:
Rachel M. McQuade, Lewis M. Singleton, Hongyi Wu, Sophie Lee, Remy Constable, Madeleine Di Natale, Mitchell T. Ringuet, Joel P. Berger, Jessica Kauhausen, Clare L. Parish, David I. Finkelstein, John B. Furness, Shanti Diwakarla
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Parkinson’s disease (PD) is associated with neuronal damage in the brain and gut. This work compares changes in the enteric nervous system (ENS) of commonly used mouse models of PD that exhibit central neuropathy and a gut phenotype. Enter
Externí odkaz:
https://doaj.org/article/84b393003cc04c729aedad1290f826e6
Publikováno v:
Physiology. 38
Functional gastrointestinal disorders such as gastroparesis and achalasia can be caused by changes in the stomach’s intrinsic neural circuitry, the enteric nervous system. We used electrophysiological, immunohistochemistry and lesion techniques to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac0692c795ed23aff3cafe1c6af8948e
https://doi.org/10.1152/physiol.2023.38.s1.5729702
https://doi.org/10.1152/physiol.2023.38.s1.5729702
Autor:
Madeleine Di Natale, Billie Hunne, Juan C Molero, John B. Furness, Lauren Patten, Zhongming Liu, Xiaokai Wang, Martin J. Stebbing
Publikováno v:
Journal of Anatomy. 240:711-723
The strengths, directions and coupling of the movements of the stomach depend on the organisation of its musculature. Although the rat has been used as a model species to study gastric function, there is no detailed, quantitative study of the arrange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca21f07a1a41005dde975a3d96a44eb2
https://doi.org/10.1111/joa.13587
https://doi.org/10.1111/joa.13587
Autor:
David Finkelstein, Remy Constable, Shanti Diwakarla, Paul A. Adlard, Xin‐yi Chai, John B. Furness, Victoria A. Lawson, Robert A. Cherny, Kevin J. Barnham, Madeleine Di Natale, Hongyi Wu, Olivia Artaiz, Enie Lei, Rachel M McQuade
Publikováno v:
Journal of Parkinson's Disease
Background: Gastrointestinal (GI) complications, that severely impact patient quality of life, are a common occurrence in patients with Parkinson’s disease (PD). Damage to enteric neurons and the accumulation of alpha-synuclein in the enteric nervo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660536ea82e093195135dcf586127959
https://doi.org/10.3233/jpd-212731
https://doi.org/10.3233/jpd-212731
Autor:
Terry L. Powley, Billie Hunne, Deborah Jaffey, Linda J Fothergill, Kent C. Sasse, Martin J. Stebbing, John B. Furness, Lalita Oparija-Rogenmozere, Sean M. Ward, Madeleine Di Natale
Publikováno v:
Cell Tissue Res
The stomach acts as a buffer between the ingestion of food and its processing in the small intestine. It signals to the brain to modulate food intake and it in turn regulates the passage of a nutrient-rich fluid, containing partly digested food, into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405e113308d5eea5b3ef378247889ccf
https://doi.org/10.1007/s00441-020-03294-7
https://doi.org/10.1007/s00441-020-03294-7
Autor:
Shanti Diwakarla, Mitchell T Ringuet, David Finkelstein, Hongyi Wu, Madeleine Di Natale, Remy Constable, Clare L. Parish, John B. Furness, Rachel M McQuade, Lewis M Singleton, Joel Berger, Sophie Lee, Jessica A. Kauhausen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Parkinson’s disease (PD) is associated with neuronal damage in the brain and gut. This work compares changes in the enteric nervous system (ENS) of commonly used mouse models of PD that exhibit central neuropathy and a gut phenotype. Enteric neurop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce082c83534a7f9a146c204aba545be0
https://pubmed.ncbi.nlm.nih.gov/33846426
https://pubmed.ncbi.nlm.nih.gov/33846426
Autor:
Ruslan V Pustovit, Yasuhiro Tsukimi, Madeleine Di Natale, Juan C Molero, Stuart M. Brierley, John B. Furness, Sonia Garcia-Caraballo, Andrea M. Harrington
Publikováno v:
Neurogastroenterology & Motility. 32
Background Muscarinic receptor 1 positive allosteric modulators (M1PAMs) enhance colonic propulsive contractions and defecation through the facilitation of M1 receptor (M1R)-mediated signaling. We examined M1R expression in the colons of 5 species an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acdb8e13fdcf316969bdd5ab19ca8826
https://doi.org/10.1111/nmo.13866
https://doi.org/10.1111/nmo.13866
Autor:
David Finkelstein, Xin‐yi Chai, Clare L. Parish, Charlotte M. Ermine, Rachel M McQuade, Ruslan V Pustovit, Shanti Diwakarla, John B. Furness, Madeleine Di Natale
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 32(9)
Background Gastrointestinal (GI) dysfunction, including constipation, is a common non-motor symptom of Parkinson's disease (PD). The toxin 6-hydroxydopamine (6OHDA) produces the symptoms of PD, surprisingly including constipation, after it is injecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2433d92cbd6cd6b9e556a106b98f8e
https://pubmed.ncbi.nlm.nih.gov/32512642
https://pubmed.ncbi.nlm.nih.gov/32512642
Autor:
Yasuhiro, Tsukimi, Ruslan V, Pustovit, Andrea M, Harrington, Sonia, Garcia-Caraballo, Stuart M, Brierley, Madeleine, Di Natale, Juan C, Molero, John B, Furness
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 32(8)
Muscarinic receptor 1 positive allosteric modulators (M1PAMs) enhance colonic propulsive contractions and defecation through the facilitation of M1 receptor (M1R)-mediated signaling. We examined M1R expression in the colons of 5 species and compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6880e6306624b1cfd9b2fdd8ae42fee
https://pubmed.ncbi.nlm.nih.gov/32337809
https://pubmed.ncbi.nlm.nih.gov/32337809
Publikováno v:
Autonomic Neuroscience. 234:102816
This review traces the history of the discovery and subsequent understanding of smooth muscle cells and their motor innervation. Smooth muscle tissue is made up of thousands of very small, individual, electrically connected, muscle cells. Each axon t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f51761c31f8f0f64a35cfb99ee8284
https://doi.org/10.1016/j.autneu.2021.102816
https://doi.org/10.1016/j.autneu.2021.102816