Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Madeleine C. Mankowski"'
Autor:
Lei Peng, Yingxia Hu, Madeleine C. Mankowski, Ping Ren, Rita E. Chen, Jin Wei, Min Zhao, Tongqing Li, Therese Tripler, Lupeng Ye, Ryan D. Chow, Zhenhao Fang, Chunxiang Wu, Matthew B. Dong, Matthew Cook, Guilin Wang, Paul Clark, Bryce Nelson, Daryl Klein, Richard Sutton, Michael S. Diamond, Craig B. Wilen, Yong Xiong, Sidi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Despite effective vaccines against SARS-CoV-2, therapeutic options such as anti-virals and neutralizing antibodies are critical in treating disease, especially given the breakthrough infections of emerging VOCs. Here, Peng et al. generate two potent
Externí odkaz:
https://doaj.org/article/3c2da467436042e1868fd384b454c96c
Autor:
Megan E. May, Christopher W. Pohlmeyer, Abena K. Kwaa, Madeleine C. Mankowski, Justin R. Bailey, Joel N. Blankson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Elite controllers or suppressors (ES) are HIV-1 infected individuals who maintain undetectable viral loads without anti-retroviral therapy. The HLA-B*57 allele is overrepresented in ES suggesting a role for HIV-specific CD8+ T cells in immune control
Externí odkaz:
https://doaj.org/article/1ce5cc9e9bf04fa889d580efc1b6f35c
Autor:
Xiaohua Peng, Jooyoung Kim, Gayatri Gupta, Karen Agaronyan, Madeleine C. Mankowski, Asawari Korde, Shervin S. Takyar, Hyeon Jun Shin, Victoria Habet, Sarah Voth, Jonathon P. Audia, De Chang, Xinran Liu, Lin Wang, Ying Cai, Xuefei Tian, Shuta Ishibe, Min-Jong Kang, Susan Compton, Craig B. Wilen, Charles S. Dela Cruz, Lokesh Sharma
Publikováno v:
J Immunol
Postviral bacterial infections are a major health care challenge in coronavirus infections, including COVID-19; however, the coronavirus-specific mechanisms of increased host susceptibility to secondary infections remain unknown. In humans, coronavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff4035f72601e99b99568611f973b8a
https://doi.org/10.4049/jimmunol.2200198
https://doi.org/10.4049/jimmunol.2200198
Autor:
Ramy El-Diwany, Valerie J Cohen, Madeleine C Mankowski, Lisa N Wasilewski, Jillian K Brady, Anna E Snider, William O Osburn, Ben Murrell, Stuart C Ray, Justin R Bailey
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006235 (2017)
Broadly-neutralizing monoclonal antibodies (bNAbs) may guide vaccine development for highly variable viruses including hepatitis C virus (HCV), since they target conserved viral epitopes that could serve as vaccine antigens. However, HCV resistance t
Externí odkaz:
https://doaj.org/article/44a6145c372e45efb14552217bf17a32
Autor:
Xinwen Zhu, Stefan Golfier, Richard Li, Chang-Yu Chang, Julia Borden, Alvaro Sanchez, María Rebolleda-Gómez, Madeline Bender, Paul Gerald L. Sanchez, Sylvie Estrela, Madeleine C. Mankowski, Juan Diaz-Colunga, Molly Bassette, Jean C. C. Vila, Rachel Waymack
Publikováno v:
Nature ecology & evolution, vol 5, iss 7
Nature ecology & evolution
Nature ecology & evolution
Directed evolution has been used for decades to engineer biological systems at or below the organismal level. Above the organismal level, a small number of studies have attempted to artificially select microbial ecosystems, with uneven and generally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f31e0c95d96da3d34c14132261198f7
https://escholarship.org/uc/item/03j1z1qv
https://escholarship.org/uc/item/03j1z1qv
Autor:
Madeleine C. Mankowski, Andrea L. Cox, Andrew I. Flyak, Guido Massaccesi, Stuart C. Ray, Justin R. Bailey, Michelle D. Colbert, William O. Osburn, Valerie J. Kinchen, James E. Crowe
Publikováno v:
Journal of Clinical Investigation. 129:4786-4796
A vaccine for hepatitis C virus (HCV) is urgently needed. Development of broadly neutralizing plasma antibodies during acute infection is associated with HCV clearance, but the viral epitopes of these plasma antibodies are unknown. Identifying these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cceb03877a8c42bea3bd230b159682ce
https://doi.org/10.1172/jci130720
https://doi.org/10.1172/jci130720
Autor:
Madison S. Strine, Benhur Lee, Craig B. Wilen, Kasopefoluwa Y. Oguntuyo, Ruth E Hanna, Jennifer S. Chen, Katerina Politi, Fernando J. de Miguel, David van Dijk, Shang-Min Zhang, Madeleine C. Mankowski, Brett D. Lindenbach, Laura Abriola, Peter C DeWeirdt, John G. Doench, Mia Madel Alfajaro, Matthew D. Simon, Renata B. Filler, Victor Gasque, Vincent R. Graziano, Cameron O. Schmitz, Yulia V. Surovtseva, William J. Lu-Culligan, Huacui Chen, Jin Wei, Qin Yan, Robert C. Orchard
Publikováno v:
Cell
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding of coronavirus disease 2019 (COVID-19) pathogenesis. Here we performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d516c265a01dd8e282494618d787a58c
https://pubmed.ncbi.nlm.nih.gov/33147444
https://pubmed.ncbi.nlm.nih.gov/33147444
Autor:
Julia Borden, Chang-Yu Chang, Sylvie Estrela, Juan Diaz-Colunga, Jean C. C. Vila, Xinwen Zhu, Madeleine C. Mankowski, Richard Li, Paul Gerald L. Sanchez, Rachel Waymack, Molly Bassette, María Rebolleda-Gómez, Madeline Bender, Alvaro Sanchez, Stefan Golfier
Directed evolution has been used for decades to engineer biological systems from the top-down. Generally, it has been applied at or below the organismal level, by iteratively sampling the mutational landscape in a guided search for genetic variants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af6e4885a17d0dd8fa812f7f91b9c7bd
https://doi.org/10.1101/2020.07.24.214775
https://doi.org/10.1101/2020.07.24.214775
Autor:
Mia Madel Alfajaro, Victor Gasque, Huacui Chen, Madeleine C. Mankowski, David van Dijk, Kasopefoluwa Y. Oguntuyo, William J. Lu-Culligan, Jennifer S. Chen, John G. Doench, Fernando J. de Miguel, Madison S. Strine, Qin Yan, Cigall Kadoch, Cameron O. Schmitz, Robert C. Orchard, Brett D. Lindenbach, Benhur Lee, Vincent R. Graziano, Yulia V. Surovtseva, Ajinkya Patil, Renata B. Filler, Matthew D. Simon, Shang Min Zhang, Jin Wei, Craig B. Wilen, Ruth E Hanna, Wesley L. Cai, Peter C DeWeirdt, Laura Abriola, Katerina Politi, Neal G. Ravindra
Publikováno v:
Cell
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding of coronavirus disease 2019 (COVID-19) pathogenesis. Here we performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10caca28c9020fcd69ed69e8647cd9c1
https://doi.org/10.1016/j.cell.2020.10.028
https://doi.org/10.1016/j.cell.2020.10.028
Autor:
Lisa N. Wasilewski, Madeleine C. Mankowski, Justin R. Bailey, James E. Crowe, Valerie J. Kinchen, Andrew I. Flyak, Stuart C. Ray
There is an urgent need for a vaccine to combat the hepatitis C virus (HCV) pandemic, and induction of broadly neutralizing monoclonal antibodies (bNAbs) against HCV is a major goal of vaccine development. Even within HCV genotype 1, no single bNAb e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8da82b093f3ba909e344baa536b8d7f
https://resolver.caltech.edu/CaltechAUTHORS:20171219-074244603
https://resolver.caltech.edu/CaltechAUTHORS:20171219-074244603