Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Madeleine C Klein"'
Publikováno v:
eLife, Vol 7 (2018)
Pain behaviors in a Fabry mouse model are associated with the accumulation of a fat molecule that disrupts sodium ion channels in small fiber neurons.
Externí odkaz:
https://doaj.org/article/d5576465d7bf4a99a96f8ab902437b4c
Autor:
Elisabeth S. Butz, Mika O. Ruonala, Uma Chandrachud, Anton Petcherski, Stephen J. Haggarty, Surya A. Reis, Wen-Ning Zhao, Madeleine C Klein, Susan L. Cotman
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
Alterations in the autophagosomal&ndash
lysosomal pathway are a major pathophysiological feature of CLN3 disease, which is the most common form of childhood-onset neurodegeneration. Accumulating autofluorescent lysosomal storage material in CLN3
lysosomal pathway are a major pathophysiological feature of CLN3 disease, which is the most common form of childhood-onset neurodegeneration. Accumulating autofluorescent lysosomal storage material in CLN3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6748895c2beba6f340e22eb02091dd8f
http://publikationen.ub.uni-frankfurt.de/files/51693/container.zip
http://publikationen.ub.uni-frankfurt.de/files/51693/container.zip
Autor:
Stephanie Norton, Uma Chandrachud, Anton Petcherski, Sasja Heetveld, Stephen J. Haggarty, Pavlina Wolf, Hye Jin Oh, Susan L. Cotman, Madeleine C Klein, Alexandra M. Simas, Wen-Ning Zhao, Mathew W. Walker, Emyr Lloyd-Evans
Publikováno v:
Journal of Biological Chemistry. 290:14361-14380
Abnormal accumulation of undigested macromolecules, often disease-specific, is a major feature of lysosomal and neurodegenerative disease and is frequently attributed to defective autophagy. The mechanistic underpinnings of the autophagy defects are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace6ca77dfebd7e3e4eacc54e024612c
https://doi.org/10.1074/jbc.m114.621706
https://doi.org/10.1074/jbc.m114.621706
Autor:
Oaklander, Anne Louise, Mills, Alexander J., Kelley, Mary, Toran, Lisa S., Smith, Bryan, Dalakas, Marinos C., Nath, Avindra
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation; May2022, Vol. 9 Issue 3, p1-6, 6p
Publikováno v:
Annals of Neurology; Oct2020 Supplement S25, Vol. 88, pS1-S280, 280p
Publikováno v:
Annals of Neurology; Oct2019 Supplement S24, Vol. 86, pS1-S285, 285p
Publikováno v:
Pain & Central Nervous System Week; 1/26/2024, p482-482, 1p
Autor:
Petcherski, Anton1,2 (AUTHOR) apetcherski@mednet.ucla.edu, Chandrachud, Uma1 (AUTHOR) uchandrachud@mgh.harvard.edu, Butz, Elisabeth S.1 (AUTHOR) ebutz1@mgh.harvard.edu, Klein, Madeleine C.1 (AUTHOR) mcklein@mgh.harvard.edu, Zhao, Wen-Ning1 (AUTHOR) wnzhao@mgh.harvard.edu, Reis, Surya A.1 (AUTHOR) sreis@mgh.harvard.edu, Haggarty, Stephen J.1 (AUTHOR) shaggarty@mgh.harvard.edu, Ruonala, Mika O.2 (AUTHOR), Cotman, Susan L.1 (AUTHOR) scotman@mgh.harvard.edu
Publikováno v:
Cells (2073-4409). Dec2019, Vol. 8 Issue 12, p1531-1531. 1p.
Publikováno v:
eLife; 2018, p1-3, 3p