Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Madeleine, Morrissette"'
Autor:
Jaclyn Y. Lock, Mariaelena Caboni, Philip Strandwitz, Madeleine Morrissette, Kevin DiBona, Brian A. Joughin, Kim Lewis, Rebecca L. Carrier
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Considerable effort has been put forth to understand mechanisms by which the microbiota modulates and responds to inflammation. Here, we explored whether oxidation metabolites produced by the host during inflammation, sodium nitrate and trimethylamin
Externí odkaz:
https://doaj.org/article/9e96cdbf33444485a4bae94618b77ab4
Autor:
Negar Shahsavari, Boyuan Wang, Yu Imai, Miho Mori, Sangkeun Son, Libang Liang, Nils Böhringer, Sylvie Manuse, Michael F. Gates, Madeleine Morrissette, Rachel Corsetti, Josh L. Espinoza, Chris L. Dupont, Michael T. Laub, Kim Lewis
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT With the overmining of actinomycetes for compounds acting against Gram-negative pathogens, recent efforts to discover novel antibiotics have been focused on other groups of bacteria. Teixobactin, the first antibiotic without detectable resis
Externí odkaz:
https://doaj.org/article/5974da801ad14cc38621f9fd57c7314a
Autor:
Madeleine Morrissette, Norman Pitt, Antonio González, Philip Strandwitz, Mariaelena Caboni, Alison W. Rebman, Rob Knight, Anthony D’Onofrio, John N. Aucott, Mark J. Soloski, Kim Lewis
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Lyme disease is the most common vector-borne disease in the United States, with an estimated incidence of 300,000 infections annually. Antibiotic intervention cures Lyme disease in the majority of cases; however, 10 to 20% of patients develo
Externí odkaz:
https://doaj.org/article/6ce4b7f151484fb790e5b749f9d0ebd2
Autor:
Yu Imai, Glenn Hauk, Jeffrey Quigley, Libang Liang, Sangkeun Son, Meghan Ghiglieri, Michael F. Gates, Madeleine Morrissette, Negar Shahsavari, Samantha Niles, Donna Baldisseri, Chandrashekhar Honrao, Xiaoyu Ma, Jason J. Guo, James M. Berger, Kim Lewis
Publikováno v:
Nat Chem Biol
The antimicrobial resistance crisis requires the introduction of novel antibiotics. The use of conventional broad-spectrum compounds selects for resistance in off-target pathogens and harms the microbiome. This is especially true for Mycobacterium tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b3963934c81503b0a8f49459d249f4
https://doi.org/10.1038/s41589-022-01102-7
https://doi.org/10.1038/s41589-022-01102-7
Autor:
Kathleen O'Connor, Madeleine Morrissette, Philip Strandwitz, Meghan Ghiglieri, Mariaelena Caboni, Haiyan Liu, Christina Khoo, Anthony D'Onofrio, Kim Lewis
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224836 (2019)
The opportunistic pathogen Escherichia coli, a common member of the human gut microbiota belonging to the Enterobacteriaceae family, is the causative agent of the majority of urinary tract infections (UTIs). The gut microbiota serves as a reservoir f
Externí odkaz:
https://doaj.org/article/84a9f67c2cd44853b37856dd066e9a1a
Autor:
Jaclyn Y, Lock, Mariaelena, Caboni, Philip, Strandwitz, Madeleine, Morrissette, Kevin, DiBona, Brian A, Joughin, Kim, Lewis, Rebecca L, Carrier
Publikováno v:
Gut microbes. 14(1)
Considerable effort has been put forth to understand mechanisms by which the microbiota modulates and responds to inflammation. Here, we explored whether oxidation metabolites produced by the host during inflammation, sodium nitrate and trimethylamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c026bf1dee0f288f095efdd7e5df093
https://pubmed.ncbi.nlm.nih.gov/35316142
https://pubmed.ncbi.nlm.nih.gov/35316142
Autor:
Ryan D. Miller, Akira Iinishi, Seyed Majed Modaresi, Byung-Kuk Yoo, Thomas D. Curtis, Patrick J. Lariviere, Libang Liang, Sangkeun Son, Samantha Nicolau, Rachel Bargabos, Madeleine Morrissette, Michael F. Gates, Norman Pitt, Roman P. Jakob, Parthasarathi Rath, Timm Maier, Andrey G. Malyutin, Jens T. Kaiser, Samantha Niles, Blake Karavas, Meghan Ghiglieri, Sarah E. J. Bowman, Douglas C. Rees, Sebastian Hiller, Kim Lewis
Publikováno v:
Nature microbiology. 7(10)
Discovery of antibiotics acting against Gram-negative species is uniquely challenging due to their restrictive penetration barrier. BamA, which inserts proteins into the outer membrane, is an attractive target due to its surface location. Darobactins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c797093054e197dc1d0d3e3fbf7d1f5
https://pubmed.ncbi.nlm.nih.gov/36163502
https://pubmed.ncbi.nlm.nih.gov/36163502
Autor:
Xiaoqian Wu, Yu Imai, Samta Jain, Sangkeun Son, Gabriel Fox, Helen I. Zgurskaya, Inga V. Leus, Yury S. Polikanov, Quentin Favre-Godal, Rachel Bargabos, Madeleine Morrissette, Akira Iinishi, Linden T. Hu, Anthony D'Onofrio, Meghan Ghiglieri, Steven J. Norris, Kim Lewis, Cecily A. Freliech, Norman Pitt, Mariaelena Caboni, Megan Krumpoch, Julie E. McCarthy, Vincent Bonifay, Diane G. Edmondson, Rachel Corsetti, Dorota Klepacki, Nadja Leimer, Samantha Niles
Publikováno v:
Cell
Summary Lyme disease is on the rise. Caused by a spirochete Borreliella burgdorferi, it affects an estimated 500,000 people in the United States alone. The antibiotics currently used to treat Lyme disease are broad spectrum, damage the microbiome, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab36912358f165c45496478ef1f5dc1
https://europepmc.org/articles/PMC8526400/
https://europepmc.org/articles/PMC8526400/
Autor:
Mark J. Soloski, Anthony D'Onofrio, Philip Strandwitz, Alison W. Rebman, Antonio Gonzalez, Mariaelena Caboni, Madeleine Morrissette, John N. Aucott, Rob Knight, Norman Pitt, Kim Lewis
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
mBio
mBio, vol 11, iss 5
mBio
mBio, vol 11, iss 5
Most patients with acute Lyme disease are cured with antibiotic intervention, but 10 to 20% endure debilitating symptoms such as fatigue, neurological complications, and myalgias after treatment, a condition known as posttreatment Lyme disease syndro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4736562826b7ad293c19454b0523a04d
https://journals.asm.org/doi/10.1128/mBio.02310-20
https://journals.asm.org/doi/10.1128/mBio.02310-20