Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Madelaine Skolastika Theardy"'
Autor:
Stella Amanda, Tze King Tan, Jolynn Zu Lin Ong, Madelaine Skolastika Theardy, Regina Wan Ju Wong, Xiao Zi Huang, Muhammad Zulfaqar Ali, Yan Li, Zhiyuan Gong, Hiroshi Inagaki, Ee Yong Foo, Brendan Pang, Soo Yong Tan, Shinsuke Iida, Takaomi Sanda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
IRF4 is a regulator of immune function, and is overexpressed in lymphoid neoplasms. Here, the authors utilise single cell RNA-seq to show the abundance of double-negative T cells in IRF4 driven zebrafish tumour models, and identify sensitivity of the
Externí odkaz:
https://doaj.org/article/ff3debb04d284c5488577eed6625143c
Autor:
Fang Qi Lim, Allison Si-Yu Chan, Rui Yokomori, Xiao Zi Huang, Madelaine Skolastika Theardy, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
T-cell acute lymphoblastic leukemia (T-ALL) is a malignancy of thymic T-cell precursors. Overexpression of oncogenic transcription factor TAL1 is observed in 40-60% of human T-ALL cases, frequently together with activation of the NOTCH1 and PI3K-AKT
Externí odkaz:
https://doaj.org/article/41fbefeee4bf462ca1a3441c3663a321
Publikováno v:
Cancers. 14(17)
IRF4 is a transcription factor in the interferon regulatory factor (IRF) family. Since the discovery of this gene, various research fields including immunology and oncology have highlighted the unique characteristics and the importance of IRF4 in sev
Autor:
Stella Amanda, Tze King Tan, Jolynn Zu Lin Ong, Madelaine Skolastika Theardy, Regina Wan Ju Wong, Xiao Zi Huang, Muhammad Zulfaqar Ali, Li Yan, Zhiyuan Gong, Hiroshi Inagaki, Ee Yong Foo, Brendan Pang, Soo Yong Tan, Shinsuke Iida, Takaomi Sanda
Publikováno v:
Cancer Research. 82:LB018-LB018
IRF4 is a master regulator of immunity and is also frequently overexpressed in mature lymphoid neoplasms. Here, we demonstrate the stage-specific oncogenicity of IRF4 in vivo, its potential effects on T-cell development and clonal evolution using a z
Autor:
Madelaine Skolastika Theardy, Tri Putra Dinata Giri, Anton Sumarpo, D Brilliant, Marvelmario Reginald Gabriel Salim, R. R. F. A Putra, D. D Veridianti
Publikováno v:
Advanced Science Letters. 24:6518-6521
Autor:
Josanda Sudwisutria, Wibi Sindjaja, Suvanna Visakha Wu, Tri Putra Dinata Giri, Madelaine Skolastika Theardy, Evelyn Nathalia, Anton Sumarpo, Moreno Zanardi
Publikováno v:
Advanced Science Letters. 24:6846-6851
Autor:
Madelaine Skolastika Theardy, Sharleen Elvira, Evelyn Nathalia, Graciella Rosellinny, Anton Sumarpo, Michael Putra Utama, Andrew Steven Liyanto
Publikováno v:
Romanian Journal of Internal Medicine, Vol 56, Iss 3, Pp 135-142 (2018)
Introduction. LIM Homeobox 6 (LHX6) encodes a LIM homeodomain transcription factor, contributes to tissue development and morphogenesis, and is mostly expressed in medial ganglionic eminence and odontogenic mesenchyme. However, it has been reported t