Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Madelaine C Brearley"'
Autor:
David M Loczenski-Brown, Sarah Jones, Jeni Luckett, Zoe Daniel, Madelaine C Brearley, Francis J P Ebling, Tim Parr, John M Brameld
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218970 (2019)
We previously identified PEPCK-M (encoded by the Pck2 gene) to be highly up-regulated in skeletal muscle of pigs treated with Ractopamine, an anabolic beta-adrenergic receptor agonist. To determine whether PEPCK-M had a causative role in modulating t
Externí odkaz:
https://doaj.org/article/ce45a43db3ba476a8eba772051145243
Autor:
David M Brown, Sarah Jones, Zoe C T R Daniel, Madelaine C Brearley, Jo E Lewis, Francis J P Ebling, Tim Parr, John M Brameld
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201481 (2018)
Previously, we highlighted induction of an integrated stress response (ISR) gene program in skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the hypothesis that the ER-stress inhibitor, sodium 4-phenylbutyrate (PBA), wo
Externí odkaz:
https://doaj.org/article/5bdead5ccbf14368938869e7b13b2b57
Autor:
Madelaine C. Brearley-Sholto, David M. Loczenski-Brown, Sarah Jones, Zoe C. T. R. Daniel, Francis J. P. Ebling, Tim Parr, John M. Brameld
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract We previously reported that growth promoter-induced skeletal muscle hypertrophy co-ordinately upregulated expression of genes associated with an integrated stress response (ISR), as well as potential ISR regulators. We therefore used Adeno-A
Externí odkaz:
https://doaj.org/article/eba2dd6150b34a2499ec3b93f21df763
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 mus
Externí odkaz:
https://doaj.org/article/700ab5aa868d43ae891ddb46d418f63a
Autor:
Xu Xiao, John Paul Kennelly, Alessandra Ferrari, Bethan L. Clifford, Emily Whang, Yajing Gao, Kevin Qian, Jaspreet Sandhu, Kelsey E. Jarrett, Madelaine C. Brearley-Sholto, Alexander Nguyen, Rohith T. Nagari, Min Sub Lee, Sicheng Zhang, Thomas A. Weston, Stephen G. Young, Steven J. Bensinger, Claudio J. Villanueva, Thomas Q. de Aguiar Vallim, Peter Tontonoz
Publikováno v:
Nature Metabolism. 5:165-181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf87f0f77365706f3d61f11548901e5
https://doi.org/10.1038/s42255-022-00722-6
https://doi.org/10.1038/s42255-022-00722-6
Autor:
Nicolò, Ilacqua, Irene, Anastasia, Danylo, Aloshyn, Rana, Ghandehari-Alavijeh, Emily Ann, Peluso, Madelaine C, Brearley-Sholto, Leonardo V, Pellegrini, Andrea, Raimondi, Thomas Q, de Aguiar Vallim, Luca, Pellegrini
Publikováno v:
Biology Direct. 17
Background In mouse liver hepatocytes, nearly half of the surface area of every mitochondrion is covered by wrappER, a wrapping-type of ER that is rich in fatty acids and synthesizes lipoproteins (VLDL) (Anastasia et al. in Cell Rep 34:108873, 2021;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2bd110bc3930ac05cfa51f9b0c54c5
https://doi.org/10.1186/s13062-022-00344-8
https://doi.org/10.1186/s13062-022-00344-8
Autor:
John M. Brameld, Zoe Daniel, Francis J. P. Ebling, Tim Parr, David M. Loczenski-Brown, Sarah Jones, Madelaine C. Brearley-Sholto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
We previously reported that growth promoter-induced skeletal muscle hypertrophy co-ordinately upregulated expression of genes associated with an integrated stress response (ISR), as well as potential ISR regulators. We therefore used Adeno-Associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6168c08aee1b147c9931a249c5256b97
https://doi.org/10.1038/s41598-021-99432-4
https://doi.org/10.1038/s41598-021-99432-4
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100924-(2021)
Myosin heavy chain-IIB (MyHC-IIB; encoded by MYH4 or Myh4) expression is often associated with muscle hypertrophic growth. Unlike other large mammals, domestic pig breeds express MyHC-IIB at both the mRNA and protein level. Aim To utilise a fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec85d207eb24ac2028de3e0b6d08035
http://www.sciencedirect.com/science/article/pii/S2405580821000182
http://www.sciencedirect.com/science/article/pii/S2405580821000182
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 muscle cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318b099a6fa1fb1d87d51676966555ef
https://doi.org/10.1038/s41598-020-79324-9
https://doi.org/10.1038/s41598-020-79324-9
Publikováno v:
Biochemistry and Biophysics Reports
Myosin heavy chain-IIB (MyHC-IIB; encoded by MYH4 or Myh4) expression is often associated with muscle hypertrophic growth. Unlike other large mammals, domestic pig breeds express MyHC-IIB at both the mRNA and protein level. Aim To utilise a fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::101250141a9fe02a39a8827c596334bb
https://pubmed.ncbi.nlm.nih.gov/33614996
https://pubmed.ncbi.nlm.nih.gov/33614996