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PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation.

Autor: Palanivel C; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Madduri LSV; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Hein AL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Jenkins CB; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Graff BT; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Camero AL; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA.; Department of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA., Zhou S; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Enke CA; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Ouellette MM; Department of Internal Medicine - Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198, USA.; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA., Yan Y; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA.; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Publikováno v: Aging [Aging (Albany NY)] 2024 Mar 04; Vol. 16 (5), pp. 4116-4137. Date of Electronic Publication: 2024 Mar 04.