Mapping of Data-Sharing Repositories for Paediatric Clinical Research—A Rapid Review

Autor: Mariagrazia Felisi, Fedele Bonifazi, Maddalena Toma, Claudia Pansieri, Rebecca Leary, Victoria Hedley, Ronald Cornet, Giorgio Reggiardo, Annalisa Landi, Annunziata D’Ercole, Salma Malik, Sinéad Nally, Anando Sen, Avril Palmeri, Donato Bonifazi, Adriana Ceci

Publikováno v: Data, Vol 9, Iss 4, p 59 (2024)

The reuse of paediatric individual patient data (IPD) from clinical trials (CTs) is essential to overcome specific ethical, regulatory, methodological, and economic issues that hinder the progress of paediatric research. Sharing data through reposito

Externí odkaz: https://doaj.org/article/9158e49a93a246568a90d8f1c50b1cc2

Overview of the European post-authorisation study register post-authorization studies performed in Europe from September 2010 to December 2018

Autor: Janet, Sultana, Salvatore, Crisafulli, Mariana, Almas, Ippazio Cosimo, Antonazzo, Esme, Baan, Claudia, Bartolini, Maria Paola, Bertuccio, Fedele, Bonifazi, Annalisa, Capuano, Antonella, Didio, Vera, Ehrenstein, Mariagrazia, Felisi, Carmen, Ferrajolo, Andrea, Fontana, Remy, Francisca, Annie, Fourrier-Reglat, Joan, Fortuny, Rosa, Gini, Giulia, Hyeraci, Christel, Hoeve, Christos, Kontogiorgis, Valentina, Isgrò, Panagiotis-Nikolaos, Lalagkas, Luca, L'Abbate, Deborah, Layton, Annalisa, Landi, Silvia, Narduzzi, Leonardo, Roque Pereira, Georgios, Poulentzas, Concetta, Rafaniello, Giuseppe, Roberto, Giulia, Scondotto, Liberata, Sportiello, Maddalena, Toma, Massoud, Toussi, Katia, Verhamme, Elisabetta, Volpe, Gianluca, Trifirò

Publikováno v: Sultana, J, Crisafulli, S, Almas, M, Antonazzo, I C, Baan, E, Bartolini, C, Bertuccio, M P, Bonifazi, F, Capuano, A, Didio, A, Ehrenstein, V, Felisi, M, Ferrajolo, C, Fontana, A, Francisca, R, Fourrier-Reglat, A, Fortuny, J, Gini, R, Hyeraci, G, Hoeve, C, Kontogiorgis, C, Isgrò, V, Lalagkas, P N, L'Abbate, L, Layton, D, Landi, A, Narduzzi, S, Roque Pereira, L, Poulentzas, G, Rafaniello, C, Roberto, G, Scondotto, G, Sportiello, L, Toma, M, Toussi, M, Verhamme, K, Volpe, E, Trifirò, G & On behalf the Working Group 3 of ENCePP (Inventory of EU data sources and methodological approaches for multisource studies) 2022, ' Overview of the European post-authorisation study register post-authorization studies performed in Europe from September 2010 to December 2018 ', Pharmacoepidemiology and Drug Safety, vol. 31, no. 6, pp. 689-705 . https://doi.org/10.1002/pds.5413
Pharmacoepidemiology and Drug Safety, 31(6), 689-705. John Wiley & Sons Ltd.

Background: The European post-authorisation study (EU PAS) register is a repository launched in 2010 by the European Medicines Agency (EMA). All EMA-requested PAS, commonly observational studies, must be recorded in this register. Multi-database stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6526b1df943ebacfe2d9eb69112538a2
https://pubmed.ncbi.nlm.nih.gov/35092329

Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease

Autor: Leonardo Pisani, Maddalena Toma, Modesto de Candia, Olga A. Ivanova, Rosa Purgatorio, Cosimo Altomare, Leonid G. Voskressensky, Annalisa De Palma, Antonio Carrieri, Marco Catto

Publikováno v: European journal of medicinal chemistry. 177

Due to the role of butyrylcholinesterase (BChE) in acetylcholine hydrolysis in the late stages of the Alzheimer's disease (AD), inhibitors of butyrylcholinesterase (BChE) have been recently envisaged, besides acetylcholinesterase (AChE) inhibitors, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4995fd44b803d02bb1c4d8efb4faecb1
https://pubmed.ncbi.nlm.nih.gov/31158754

Elusive Therapeutic Effect of PCSK9 Inhibitors on Lipoprotein(a) Levels

Autor: Beatrice Dal Pino, Maddalena Toma, Francesco Sbrana, Andrea Ripoli, Federico Bigazzi, Tiziana Sampietro

Publikováno v: Therapeutic Apheresis and Dialysis. 23:385-386

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46aaef3c6cdb203b23e03e55eb7c067d
https://doi.org/10.1111/1744-9987.12766

Concise synthesis of thapsigargin from nortrilobolide

Autor: Maddalena Toma, Søren Brøgger Christensen, François Crestey

Publikováno v: Tetrahedron Letters. 56:5896-5898

Herein, we describe an expedient synthesis of the hexaoxygenated guaianolide thapsigargin ( 1 ), a potent inhibitor of the sarco/endoplasmic reticulum Ca 2+ -ATPase (SERCA), from the natural product nortrilobolide ( 2 ). This protocol involves three

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9239eed5080ce9922283a9dd72b2ccc6
https://doi.org/10.1016/j.tetlet.2015.09.024